Opportunity Information: Apply for PA 07 254
Apply for PA 07 254
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Cancer Surveillance Using Health Claims Based Data (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes 93.399 Cancer Control.
- This funding opportunity was created on Dec 5, 2008 and posted on Dec 20, 2006.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Small businesses Special district governments Independent school districts City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Cancer Surveillance Using Health Claims Based Data (R01) opportunity (Funding Opportunity Number PA 07 254) is a discretionary NIH grant announcement led by the National Cancer Institute (NCI) in collaboration with the Agency for Healthcare Research and Quality (AHRQ). It is designed to support research projects that use administrative health insurance claims data as a core resource for cancer surveillance. In this context, "cancer surveillance" goes beyond counting cases and includes studying how cancer care is delivered in real-world settings, what patients receive over time, and how care relates to outcomes, quality, costs, and equity.
A central aim of the announcement is to encourage investigators to use claims-based datasets to evaluate patterns of care across the full cancer care continuum. That can include diagnostic workups, initial treatment selection, surgery, radiation, systemic therapy, follow-up care, management of complications, survivorship care, end-of-life care, and longer-term outcomes that can be inferred from utilization patterns. The FOA explicitly highlights research on quality and outcomes of care, and it also emphasizes health disparities, meaning projects can examine whether outcomes or access to appropriate care differ across groups defined by race and ethnicity, geography, socioeconomic status, insurance type, age, disability status, or other factors that can be measured or approximated within claims-linked data environments.
The scope is broad in terms of analytic focus. Projects may concentrate on patient-level treatment and outcomes, such as comparing adherence to guideline-concordant care, evaluating treatment sequences, measuring service utilization, or tracking adverse events and subsequent health care needs. At the same time, the FOA welcomes work that considers provider or health-system influences, such as how institutional characteristics, clinician practice patterns, referral networks, facility volume, or regional health system factors shape cancer care and outcomes. This makes the opportunity relevant to health services researchers, cancer epidemiologists, outcomes researchers, and policy-oriented teams who can translate claims-based evidence into actionable insights for improving cancer care delivery.
The mechanism of support is the NIH Research Project Grant (R01), which generally funds more mature, hypothesis-driven projects that can be executed at full research scale. The announcement notes that it runs in parallel with a separate, scientifically identical funding opportunity that uses the R21 mechanism (PA 06 386), which is typically aimed at earlier-stage, exploratory, or developmental projects. Applicants choosing the R01 route are generally expected to propose a well-developed study with strong preliminary rationale, clear aims, and a feasible plan for obtaining and analyzing the relevant claims data.
Funding decisions are contingent on the availability of funds and the number and quality of applications received, and the FOA does not promise a set number of awards. Applications are accepted on multiple receipt dates, with specific deadlines and details provided in the full announcement. The posting date is December 20, 2006, and the opportunity was archived June 1, 2009, reflecting the original lifecycle of this particular announcement.
Eligibility is broad and includes many types of domestic organizations and governments, such as public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), state and local governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and federally recognized tribal governments as well as other tribal organizations. The eligibility statement also indicates that foreign institutions may apply, eligible federal agencies may apply, and faith-based or community-based organizations may apply. There is no cost sharing or matching requirement. The activity areas are associated with CFDA 93.226 (Research on Healthcare Costs, Quality and Outcomes) and 93.399 (Cancer Control), which signals the combined emphasis on cancer control efforts and health care delivery, cost, and outcomes research.
Operationally, this FOA is best viewed as an invitation to leverage the strengths of claims data, such as large sample sizes, longitudinal tracking of service use, and coverage of routine care across settings, to answer surveillance-oriented questions that are difficult to address with smaller clinical cohorts alone. It also implicitly recognizes common limitations of claims (for example, imperfect clinical detail or coding variability), meaning competitive projects typically require thoughtful measurement strategies, validation approaches when possible, careful cohort construction, and analytic methods appropriate for observational data. For applicants needing technical help accessing the full announcement online, the notice provides NIH Office of Extramural Research (OER) webmaster contact information.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled Cancer Surveillance Using Health Claims Based Data (R01).
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA-07-254.
Which agencies are sponsoring or leading this announcement?
This is a discretionary NIH grant announcement led by the National Cancer Institute (NCI) in collaboration with the Agency for Healthcare Research and Quality (AHRQ).
What is the purpose of this FOA?
The FOA is designed to support research projects that use administrative health insurance claims data as a core resource for cancer surveillance. In this context, cancer surveillance includes not only tracking cancer cases, but also examining how cancer care is delivered in real-world settings and how care relates to outcomes, quality, costs, and equity.
How does this FOA define "cancer surveillance"?
Within this announcement, cancer surveillance goes beyond counting cases. It includes studying patterns of cancer care over time, what services patients receive, and how those patterns relate to outcomes, quality of care, costs, and differences across populations.
What types of data are central to the proposed research?
The core data resource emphasized in this FOA is administrative health insurance claims data, used for surveillance-oriented analyses of cancer care and outcomes.
What parts of the cancer care continuum can be studied under this FOA?
The FOA encourages evaluating patterns of care across the full continuum, which may include diagnostic workups, initial treatment selection, surgery, radiation, systemic therapy, follow-up care, complication management, survivorship care, end-of-life care, and longer-term outcomes that can be inferred from utilization patterns.
Does the FOA emphasize cancer care quality and outcomes?
Yes. The FOA explicitly highlights research on the quality and outcomes of cancer care using claims-based datasets.
Are health disparities and equity-focused projects within scope?
Yes. The FOA emphasizes health disparities and supports projects examining whether outcomes or access to appropriate care differ across groups such as race and ethnicity, geography, socioeconomic status, insurance type, age, disability status, or other factors measurable or approximable in claims-linked data environments.
What are examples of patient-level questions that claims-based projects could address?
Projects may focus on patient-level treatment and outcomes, including comparing adherence to guideline-concordant care, evaluating treatment sequences, measuring service utilization, and tracking adverse events and related follow-on health care needs.
Can projects study provider or health-system factors, not just patients?
Yes. The FOA welcomes research on provider and health-system influences, such as institutional characteristics, clinician practice patterns, referral networks, facility volume, and regional health system factors that may shape cancer care and outcomes.
What grant mechanism is used for this opportunity?
This announcement uses the NIH Research Project Grant (R01) mechanism.
How does the R01 focus differ from the related R21 opportunity mentioned?
The FOA notes it runs in parallel with a separate, scientifically identical announcement using the R21 mechanism (PA-06-386), which is typically aimed at earlier-stage, exploratory, or developmental projects. The R01 route is generally intended for more mature, hypothesis-driven projects executed at full research scale.
What is generally expected from applicants choosing the R01 route?
Applicants pursuing the R01 are generally expected to propose a well-developed study with strong preliminary rationale, clear aims, and a feasible plan for obtaining and analyzing the relevant claims data.
Is there a guaranteed number of awards?
No. The FOA states that funding decisions depend on the availability of funds and the number and quality of applications received, and it does not promise a specific number of awards.
Are there multiple application receipt dates?
Yes. Applications are accepted on multiple receipt dates, with specific deadlines and details provided in the full announcement.
When was this FOA posted, and what is its status?
The posting date is December 20, 2006. The opportunity was archived on June 1, 2009, reflecting the original lifecycle of this announcement.
Who is eligible to apply?
Eligibility is broad. It includes many types of domestic organizations and governments such as public and private institutions of higher education; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses and other for-profits); state and local governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; and federally recognized tribal governments as well as other tribal organizations.
Are foreign institutions allowed to apply?
Yes. The eligibility statement indicates that foreign institutions may apply.
Can federal agencies apply?
Yes. The eligibility statement indicates that eligible federal agencies may apply.
Are faith-based or community-based organizations eligible?
Yes. The eligibility statement indicates that faith-based or community-based organizations may apply.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
Which CFDA activity areas are associated with this FOA?
The activity areas are associated with CFDA 93.226 (Research on Healthcare Costs, Quality and Outcomes) and CFDA 93.399 (Cancer Control).
Why does the FOA focus on claims data for cancer surveillance research?
The FOA frames claims data as valuable because they can offer large sample sizes, longitudinal tracking of service use, and coverage of routine care across settings, enabling surveillance-oriented questions that can be difficult to address using smaller clinical cohorts alone.
Does the FOA recognize limitations of claims data?
Yes. It implicitly recognizes common limitations such as imperfect clinical detail and coding variability, and it points toward the need for thoughtful measurement strategies, validation approaches when possible, careful cohort construction, and analytic methods appropriate for observational data.
Who might find this FOA especially relevant?
The opportunity is presented as relevant to health services researchers, cancer epidemiologists, outcomes researchers, and policy-oriented teams who can translate claims-based evidence into actionable insights for improving cancer care delivery.
Where is technical help mentioned for accessing the full announcement online?
For applicants needing technical help accessing the full announcement online, the notice provides contact information for the NIH Office of Extramural Research (OER) webmaster.
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| Epigenetic Approaches in Cancer Epidemiology (R21) Apply for PA 07 299 Funding Number: PA 07 299 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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| Drug Abuse Aspects of HIV/AIDS (R21) Apply for PA 07 309 Funding Number: PA 07 309 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Aspects of HIV/AIDS (R03) Apply for PA 07 308 Funding Number: PA 07 308 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Aspects of HIV/AIDS (R01) Apply for PA 07 307 Funding Number: PA 07 307 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research on Clinical Decision Making in Life Threatening Illness (R21) Apply for PA 07 316 Funding Number: PA 07 316 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Early Career Award in Chemistry of Drug Abuse and Addiction (ECHEM) NIDA (R03) Apply for PAS 07 327 Funding Number: PAS 07 327 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse, Risky Decision Making and HIV/AIDS (R03) Apply for PAS 07 326 Funding Number: PAS 07 326 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse, Risky Decision Making and HIV/AIDS (R01) Apply for PAS 07 324 Funding Number: PAS 07 324 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse, Risky Decision Making and HIV/AIDS (R21) Apply for PAS 07 325 Funding Number: PAS 07 325 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Academic Industrial Partnerships for Development and Validation of In Vivo Imaging Systems and Methods for Cancer Investigations (R01) Apply for PAR 07 214 Funding Number: PAR 07 214 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NIDA Research Education Grants in Drug Abuse and Addiction (R25) Apply for PAR 07 221 Funding Number: PAR 07 221 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Neuroscience Research on Drug Abuse (R01) Apply for PA 07 226 Funding Number: PA 07 226 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Neuroscience Research on Drug Abuse (R21) Apply for PA 07 227 Funding Number: PA 07 227 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Neuroscience Research on Drug Abuse(R03) Apply for PA 07 228 Funding Number: PA 07 228 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Collaborative Clinical Trials in Drug Abuse (R01) Apply for PAR 07 232 Funding Number: PAR 07 232 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R01) Apply for PA 07 329 Funding Number: PA 07 329 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21) Apply for PA 07 331 Funding Number: PA 07 331 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03) Apply for PA 07 330 Funding Number: PA 07 330 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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