Capacity Building through Training/Mentoring for Treatment, Care and Support including Preventing Mother-to-Child Transmission (PMTCT); TB/HIV; Health System Strengthening; and Voluntary Medical Male Circumcision in Zambia under the President’s Eme | Apply Online

Opportunity Summary:

This funding opportunity is a continuation cooperative agreement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under the Center for Global Health, focused on strengthening HIV-related service delivery in Zambia through intensive capacity building. The program centers on training and mentoring approaches that improve the quality, consistency, and sustainability of treatment, care, and support services, with an emphasis on key PEPFAR priority areas: prevention of mother-to-child transmission (PMTCT), integrated TB/HIV services, broader health system strengthening, and voluntary medical male circumcision (VMMC). In practical terms, the grant is designed to help institutions and implementing partners build and reinforce the skills, systems, and workflows needed for Zambia’s health sector to deliver high-impact HIV prevention and treatment services more effectively and at scale.

The opportunity is identified as “Capacity Building through Training/Mentoring for Treatment, Care and Support including Preventing Mother-to-Child Transmission (PMTCT); TB/HIV; Health System Strengthening; and Voluntary Medical Male Circumcision in Zambia under the President’s Emergency Plan for AIDS Relief (PEPFAR).” The official funding opportunity number is CDC RFA GH15-159703CONT17. It is categorized as “Continuation,” meaning it is intended to support ongoing work building on prior investments rather than launching an entirely new, open-ended competition. The funding instrument is a cooperative agreement, which typically signals a more hands-on partnership model where CDC may have substantial involvement in technical direction, coordination, monitoring, and alignment with PEPFAR strategies and national priorities.

Programmatically, the scope reflects a comprehensive HIV response that links clinical service delivery with system-level improvements. For HIV treatment, care, and support, the focus on training and mentoring suggests strengthening the competencies of healthcare workers and program staff in areas such as antiretroviral therapy (ART) provision, clinical monitoring, adherence support, retention in care, patient-centered case management, and quality improvement. For PMTCT, the intent is to reduce new pediatric HIV infections and improve maternal outcomes by ensuring pregnant and breastfeeding women receive timely HIV testing, immediate linkage to ART, and consistent follow-up, while also improving early infant diagnosis and continuity of care for HIV-exposed infants. For TB/HIV, the emphasis implies expanding integrated screening, diagnosis, preventive therapy where appropriate, infection control, and coordinated treatment pathways so that co-infected patients are identified quickly and managed effectively. Health system strengthening in this context typically relates to improving the foundational elements that make services reliable over time, such as data systems and monitoring, supply chain practices, laboratory and referral networks, supportive supervision structures, and facility-level management and governance. VMMC is included as a proven HIV prevention intervention, and capacity building here often involves strengthening clinical skills, safety and quality standards, demand creation approaches, and service delivery models that can reach priority populations efficiently.

The opportunity sits within the broader framework of PEPFAR, the U.S. government’s global initiative to combat HIV/AIDS. That context matters because it signals alignment with PEPFAR’s strategic goals, performance measurement culture, and expectation that funded activities contribute to measurable improvements in HIV prevention and treatment outcomes. The inclusion of multiple program areas in one award line item also indicates a push for coordinated programming rather than siloed interventions, with training and mentoring used as the main lever to embed best practices into routine service delivery across the health system.

Administratively, this opportunity is listed under the Health funding activity category and associated with CFDA number 93.067, a CDC global health assistance listing commonly used for international HIV and related public health activities. The agency anticipates up to 10 awards. The award ceiling is listed as 0, which usually means a specific maximum was not stated in the public synopsis and that final award amounts may depend on available appropriations, negotiated budgets, or continuation-year funding decisions. Eligibility is described broadly as “Others,” with details referenced in an additional eligibility text field not included in the excerpt. That phrasing is often used in federal listings when eligibility extends beyond a narrow class of applicants or when only certain pre-identified or previously funded partners are eligible under a continuation mechanism.

Key dates in the listing show a creation date of September 26, 2016, and an original closing date of November 25, 2016. These dates indicate when the continuation action or related competitive continuation process was posted and when applications or required continuation submissions were due. Because it is a continuation, it likely served to extend or modify existing cooperative agreements, maintain program momentum, and ensure uninterrupted technical assistance and capacity-building support to Zambian health facilities and implementing structures.

Overall, the grant opportunity is best understood as CDC, through PEPFAR, investing in people and systems in Zambia so that HIV services are delivered with higher quality and greater consistency across the continuum of care. By focusing on training and mentoring across PMTCT, TB/HIV integration, health system strengthening, and VMMC, the program aims to improve clinical practice, strengthen service delivery platforms, and support sustainable improvements that can be maintained by local institutions over time.

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