Opportunity Information: Apply for RFA HL 13 004
Apply for RFA HL 13 004
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Cardiovascular Research Network (CVRN) Limited Competition (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837 Cardiovascular Diseases Research.
- This funding opportunity was created on Nov 3, 2011 and posted on Nov 3, 2011.
- Applicants must submit their applications by Feb 29, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Native American tribal governments (Federally recognized) Private institutions of higher education Independent school districts State governments Small businesses For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The Cardiovascular Research Network (CVRN) Limited Competition (U54) grant opportunity, Funding Opportunity Number RFA-HL-13-004, is a National Institutes of Health (NIH) cooperative agreement designed to reshape the existing CVRN into a more formal research center over a five-year award period. This is a discretionary funding opportunity under the NIH activity framework, and it uses the U54 mechanism, which signals a cooperative agreement where NIH staff typically have substantial involvement in the planning, execution, and oversight of the funded activities compared with a standard grant. The program falls under CFDA 93.837, Cardiovascular Diseases Research, and it does not require cost sharing or matching.
A defining feature of this FOA is that it is a limited competition tied directly to the original CVRN awards. The CVRN was first funded in 2007 under RFA HL 07 011, at which time eligibility was restricted to domestic healthcare delivery organizations. Since that initial launch, the Network has built significant electronic health data resources and large databases, and the NIH intends for the new Center to expand and leverage those assets. Because the value and feasibility of the proposed Center depend heavily on continuity with these established data systems and infrastructure, applications to this FOA are restricted to organizations that were previously funded under the 2007 solicitation (RFA HL 07 011). In practical terms, while the announcement lists many general applicant categories that NIH often includes (such as state and local governments, universities, nonprofits, and certain specialized institutions), the controlling eligibility rule is the limited-competition requirement: only prior CVRN grantees from the original funding round are allowed to apply.
The overarching purpose of the CVRN Center is to strengthen and scale high-quality cardiovascular disease research in real-world, community-based care settings. The FOA emphasizes research that can directly inform clinical and health system decisions, especially intervention research and comparative effectiveness research, which focuses on evaluating which treatments, care strategies, or delivery approaches work best for which patients under typical care conditions. A major programmatic goal is to accelerate what can be learned from electronic health data systems by drawing on information generated across multiple integrated healthcare organizations. This includes using the routine clinical data captured in electronic health records and related health system databases to support robust multi-site studies, improve the speed and generalizability of evidence generation, and enable analyses that would be difficult or slow to conduct through traditional single-site research designs.
Another central goal is to expand the Network's utility as a resource for the National Heart, Lung, and Blood Institute (NHLBI) and to broaden research collaboration beyond the existing Network members. That means the Center is expected not only to perform research internally, but also to increase partnership opportunities between healthcare provider organizations in the Network and researchers based at institutions outside the Network. The intention is to create a stronger bridge between delivery system science and the broader cardiovascular research community, making it easier to propose and execute studies that use the Network's populations, data resources, and operational capabilities.
Key administrative details include the original posting date of November 3, 2011, with an original and current closing date of February 29, 2012, and an archive date of March 31, 2012. Foreign institutions are not eligible to apply, and the FOA explicitly disallows non-U.S. components of U.S. organizations and foreign components as defined by NIH policy. The full announcement was provided through an NIH link (http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-13-004.html), and the contact listed for access or technical linking issues is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs) - Cardiovascular Research Network (CVRN) Limited Competition (U54) - RFA-HL-13-004
What is the funding opportunity number and program name?
This opportunity is the Cardiovascular Research Network (CVRN) Limited Competition (U54) under Funding Opportunity Number (FON) RFA-HL-13-004.
What type of NIH award is this?
This is an NIH cooperative agreement using the U54 mechanism. A U54 cooperative agreement typically includes substantial NIH staff involvement in planning, execution, and oversight compared with a standard grant.
What does "limited competition" mean for this FOA?
"Limited competition" means the applicant pool is restricted. For this FOA, eligibility is tied directly to the original CVRN awards and is limited to organizations previously funded under the 2007 solicitation RFA HL 07 011.
Who is eligible to apply?
Only organizations that were funded under the original CVRN 2007 solicitation (RFA HL 07 011) are eligible to apply. Although general NIH applicant categories may appear in the announcement, the controlling rule is the limited-competition restriction to prior CVRN grantees from that original round.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this FOA.
Are non-U.S. components of U.S. organizations allowed?
No. The FOA explicitly disallows non-U.S. components of U.S. organizations and foreign components as defined by NIH policy.
What is the purpose of the CVRN Center supported by this FOA?
The purpose is to reshape the existing CVRN into a more formal research center over a five-year award period, strengthening and scaling high-quality cardiovascular disease research in real-world, community-based care settings.
How long is the award period?
The FOA describes a five-year award period.
What research areas or approaches does the FOA emphasize?
The FOA emphasizes research that can directly inform clinical and health system decisions, especially intervention research and comparative effectiveness research. Comparative effectiveness research focuses on evaluating which treatments, care strategies, or delivery approaches work best for which patients under typical care conditions.
What role do electronic health data and healthcare delivery settings play in this program?
A major goal is to accelerate learning from electronic health data systems across multiple integrated healthcare organizations. This includes leveraging routine clinical data captured in electronic health records and related health system databases to support robust multi-site studies and improve the speed and generalizability of evidence generation.
Why is eligibility restricted to prior CVRN awardees?
The FOA states that the value and feasibility of the proposed Center depend heavily on continuity with established electronic health data systems, large databases, and infrastructure created by the Network since its 2007 launch. Because of that reliance on existing assets, only prior CVRN grantees from the original funding round may apply.
Is cost sharing or matching required?
No. This FOA does not require cost sharing or matching.
What is the CFDA number for this program?
The program is listed under CFDA 93.837, Cardiovascular Diseases Research.
What is the overall goal for collaboration under this FOA?
The FOA aims to expand the Network's utility as a resource for the National Heart, Lung, and Blood Institute (NHLBI) and broaden research collaboration beyond existing Network members. The Center is expected to increase partnership opportunities between healthcare provider organizations in the Network and researchers at institutions outside the Network.
Does the FOA expect the Center to do more than internal Network research?
Yes. In addition to performing research internally, the Center is expected to broaden collaboration and make it easier to propose and execute studies that use the Network's populations, data resources, and operational capabilities.
When was this FOA posted?
The original posting date is November 3, 2011.
What were the application due dates (closing dates)?
The FOA lists an original and current closing date of February 29, 2012.
When was the FOA archived?
The archive date listed for this FOA is March 31, 2012.
Where can the full announcement be found?
The FOA was provided through an NIH link: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-13-004.html
Who should be contacted for access or technical linking issues with the FOA?
The contact listed for access or technical linking issues is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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