Opportunity Information: Apply for PA 07 359
Apply for PA 07 359
- The National Institutes of Health in the employment, labor and training food and nutrition health sector is offering a public funding opportunity titled "Career Enhancement Award for Stem Cell Research (K18)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233 National Center on Sleep Disorders Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Feb 2, 2009 and posted on Apr 19, 2007.
- Applicants must submit their applications by Jan 30, 2009 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses City or township governments Special district governments Small businesses Public and State controlled institutions of higher education State governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Private institutions of higher education Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Foreign institutions are not eligible to apply. Eligible agencies of the Federal Government can apply.
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Opportunity Summary:
The Career Enhancement Award for Stem Cell Research (K18), Funding Opportunity Number PA-07-359, is a National Institutes of Health (NIH) discretionary grant designed to help investigators build the specific training and career development they need to use stem cells appropriately and effectively in their research programs. The core idea behind the opportunity is that stem cell science was rapidly expanding at the time of the announcement, but many established researchers did not yet have the hands-on experience or specialized knowledge to work with stem cell systems in a rigorous, safe, and scientifically productive way. By supporting targeted career enhancement, NIH aimed to speed up the integration of stem cell approaches into a broader range of biomedical research areas.
A major motivation highlighted in the announcement is the relatively new availability of human embryonic stem cells (hESCs) and the reality that most investigators were not prepared to handle them. Working with hESCs requires practical expertise in areas like culturing and maintaining cell lines, ensuring quality and stability, applying appropriate experimental methods, and navigating the specialized standards that come with this type of research. The FOA also emphasizes that stem cell promise is not limited to embryonic sources: human adult stem cells, cord blood stem cells, and even animal stem cell models are described as having strong potential for advancing understanding of disease mechanisms and for informing strategies to treat or cure human disease. In other words, the award is meant to help researchers gain the competence needed to take advantage of these tools, rather than leaving stem cell research concentrated only among a small number of already-specialized labs.
From an administrative standpoint, this opportunity falls under the grant funding instrument category and is listed under an employment, labor, and training activity category, reflecting its focus on professional development rather than only supporting a standalone research project. It does not require cost sharing or matching funds, which reduces barriers for applicants who might not have institutional resources set aside for training-focused awards. The FOA was posted on April 19, 2007, and used multiple receipt dates, with an original closing framework that required applicants to consult the full announcement for the specific due dates. The record indicates a current closing date of January 30, 2009, and an archive date of January 31, 2009, meaning it is no longer active but remains useful as a reference point for similar NIH career development mechanisms.
Eligibility is broad across many types of U.S.-based organizations, including public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), small businesses and other for-profit organizations (with the exception noted as "for profit organizations other than small businesses" also being listed), and various government entities such as state, county, city/township, special district governments, and independent school districts. Native American tribal governments (both federally recognized and other tribal organizations) and public housing authorities/Indian housing authorities are also included. A key restriction is that foreign institutions are not eligible to apply, while eligible federal government agencies may apply. Anyone evaluating eligibility would still need to confirm the finer points in the full announcement, since NIH FOAs often include additional conditions and clarifications beyond the summary list.
The opportunity is associated with multiple NIH-related CFDA numbers spanning several major biomedical domains, including cardiovascular, lung, blood, diabetes/digestive/kidney, allergy/immunology/transplantation, microbiology/infectious diseases, and the National Center on Sleep Disorders Research. This range signals that the K18 was intended to be used across disease areas and scientific disciplines, not confined to one institute or one narrow research topic. The common thread is the use of stem cell approaches as a capability that could strengthen research in many fields once investigators are properly trained.
For applicants or researchers looking for the original details, NIH provided a full announcement link: http://grants.nih.gov/grants/guide/pa-files/PA-07-359.html. For access issues or technical problems, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs): Career Enhancement Award for Stem Cell Research (K18) - PA-07-359
What is the Career Enhancement Award for Stem Cell Research (K18) (PA-07-359)?
The Career Enhancement Award for Stem Cell Research (K18), Funding Opportunity Number PA-07-359, is a National Institutes of Health (NIH) discretionary grant focused on helping investigators obtain targeted training and career development so they can use stem cells appropriately and effectively in their research programs.
What is the main goal of this funding opportunity?
The main goal is to build investigator competence in stem cell approaches, especially for established researchers who did not yet have hands-on experience or specialized knowledge to work with stem cell systems in a rigorous, safe, and scientifically productive way.
Why did NIH create this opportunity?
The announcement highlights that stem cell science was rapidly expanding at the time, and many researchers were not prepared to adopt stem cell methods. NIH aimed to speed broader, responsible integration of stem cell approaches across biomedical research areas by supporting targeted career enhancement.
Does this award focus only on human embryonic stem cells (hESCs)?
No. While the FOA emphasizes the relatively new availability of human embryonic stem cells (hESCs) and the specialized expertise needed to work with them, it also notes the promise of human adult stem cells, cord blood stem cells, and animal stem cell models.
What kinds of skills or preparation does the FOA emphasize for working with hESCs?
The FOA points to practical expertise such as culturing and maintaining cell lines, ensuring quality and stability, applying appropriate experimental methods, and navigating specialized standards associated with this type of research.
Is this opportunity primarily for conducting a research project or for professional development?
It is positioned as a professional development-focused mechanism. Administratively, it is under a grant funding instrument and is listed under an employment, labor, and training activity category, reflecting its emphasis on training and career enhancement rather than only supporting a standalone research project.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching funds.
When was PA-07-359 posted, and is it still active?
The FOA was posted on April 19, 2007. The record indicates a current closing date of January 30, 2009, and an archive date of January 31, 2009. Based on those dates, it is no longer active.
Were there multiple application receipt dates?
Yes. The announcement used multiple receipt dates, and applicants were directed to consult the full announcement for the specific due dates.
Which organizations are eligible to apply?
Eligibility is broad across many types of U.S.-based organizations. The summary includes public and private institutions of higher education; nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status); small businesses and other for-profit organizations; and various government entities (state, county, city/township, special district governments, and independent school districts). Native American tribal governments (federally recognized and other tribal organizations) and public housing authorities/Indian housing authorities are also included. Eligible federal government agencies may apply.
Are foreign institutions eligible to apply?
No. A key restriction stated in the summary is that foreign institutions are not eligible to apply.
Does the eligibility summary contain all conditions?
Not necessarily. The summary notes that NIH FOAs often include additional conditions and clarifications beyond a brief list, so anyone evaluating eligibility would need to confirm the finer points in the full announcement.
What scientific areas or NIH domains does this opportunity relate to?
The opportunity is associated with multiple NIH-related CFDA numbers spanning major biomedical domains, including cardiovascular, lung, blood, diabetes/digestive/kidney, allergy/immunology/transplantation, microbiology/infectious diseases, and the National Center on Sleep Disorders Research. This signals the K18 was intended for use across disease areas and disciplines, with the common thread being building capacity to use stem cell approaches.
Does the FOA suggest stem cell research should be limited to a small number of specialized labs?
No. A central motivation described is to avoid leaving stem cell work concentrated among only a small number of already-specialized labs by helping more investigators gain the competence needed to adopt stem cell tools responsibly.
Where can I find the official full announcement for PA-07-359?
NIH provided the full announcement here: http://grants.nih.gov/grants/guide/pa-files/PA-07-359.html
Who is listed as a contact for access issues or technical problems?
The contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What does it mean that this is an NIH discretionary grant?
In the information provided, it is described as an NIH discretionary grant designed to support targeted training and career development so investigators can use stem cells effectively in their research programs.
What is the funding opportunity number for this program?
The funding opportunity number is PA-07-359.
What is the award mechanism called in the announcement?
The mechanism is identified as the Career Enhancement Award for Stem Cell Research (K18).
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