Opportunity Information: Apply for PA 06 365
Apply for PA 06 365
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Cell Lineage and Developmental Studies in Hearing and Balance (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders.
- This funding opportunity was created on Dec 5, 2008 and posted on Apr 24, 2006.
- Applicants must submit their applications by Jul 16, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses City or township governments Independent school districts State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education County governments Special district governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification).
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply.
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Opportunity Summary:
The Cell Lineage and Developmental Studies in Hearing and Balance (R21) funding opportunity (PA-06-365) is a National Institutes of Health (NIH) discretionary grant announcement from the National Institute on Deafness and Other Communication Disorders (NIDCD). It is focused on supporting exploratory and developmental research that advances cell lineage and developmental biology studies relevant to hearing and balance. In practical terms, the opportunity is meant to encourage early-stage, innovative projects that can clarify how cells in the auditory and vestibular systems arise, differentiate, and organize during development, with the broader goal of improving understanding of normal function and disorders affecting hearing and balance. This FOA replaces an earlier NIDCD program announcement on the same topic, indicating an updated solicitation under the NIH R21 mechanism.
The award mechanism is the NIH Exploratory/Developmental Research Grant (R21), which is designed for high-risk, high-reward, or concept-establishing projects that may not yet have extensive preliminary data. A key feature of this mechanism is that it is not renewable, so applicants are expected to use the award period to generate foundational findings, proof-of-concept data, or new tools/approaches that can position the work for a later, larger research grant. The project period can be up to two years. For budgeting, applicants may request up to $275,000 in total direct costs across the two-year period, with an explicit cap of no more than $200,000 in direct costs in any single year. While those are the stated limits, the announcement also notes that award size and duration can vary depending on the nature and scope of the proposed research, and that the total number of awards and total dollars ultimately committed will depend on the quality, cost, and duration of applications received.
Eligibility is broad and includes both for-profit and nonprofit organizations and a wide range of public and private institutions. Examples specifically referenced include universities, colleges, hospitals, laboratories, and units of state and local governments, as well as eligible federal agencies. Importantly, domestic and foreign institutions are eligible to apply, which expands participation beyond U.S.-based organizations. The eligibility listing also encompasses multiple government entity types (such as state, county, city/township, special districts, and independent school districts), higher education institutions (public/state-controlled and private), certain housing authorities, and tribal organizations, including federally recognized tribal governments and other Native American tribal organizations.
The opportunity is open with respect to who may serve as the Project Director/Principal Investigator (PD/PI). Any individual who has the expertise, capability, and access to resources needed to carry out the project may apply through an eligible institution. NIH also reiterates its standard encouragement for individuals from underrepresented racial and ethnic groups and individuals with disabilities to apply for support. In addition, applicants are allowed to submit more than one application as long as each submission is scientifically distinct, which can be useful for teams exploring multiple independent ideas or approaches within the broader topic area.
From an administrative and timing standpoint, the FOA was posted on April 24, 2006, with an original closing date of November 2, 2007, and a later current closing date listed as July 16, 2009. The archive date is August 17, 2009, indicating it is no longer an active opportunity under that specific announcement. The associated CFDA number is 93.173 (Research Related to Deafness and Communication Disorders). There is no cost sharing or matching requirement stated. The award ceiling is listed as $200,000, which aligns with the per-year cap mentioned in the budget guidance, even though the combined two-year direct cost total can be up to $275,000.
For applicants looking for the complete official details, the full announcement was hosted on the NIH grants site at the link provided in the source text (grants.nih.gov). The contact information included is for technical access and linking issues via the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV), which suggests the listed contact is primarily for web/announcement access rather than scientific or programmatic questions.
FAQs: Cell Lineage and Developmental Studies in Hearing and Balance (R21) (PA-06-365)
What is this funding opportunity?
This is an NIH discretionary funding opportunity titled "Cell Lineage and Developmental Studies in Hearing and Balance (R21)" with funding opportunity number PA-06-365. It is issued by the National Institute on Deafness and Other Communication Disorders (NIDCD).
What type of grant mechanism does it use?
The announcement uses the NIH Exploratory/Developmental Research Grant mechanism (R21), which supports exploratory and developmental research.
What kinds of projects is this FOA designed to support?
It is focused on exploratory and developmental research that advances cell lineage and developmental biology studies relevant to hearing and balance, including research that clarifies how cells in the auditory and vestibular systems arise, differentiate, and organize during development.
What is the broader goal of the research supported by this FOA?
The broader goal is to improve understanding of normal function and disorders affecting hearing and balance by advancing knowledge of developmental processes in the auditory and vestibular systems.
Is this opportunity meant for early-stage or innovative work?
Yes. The R21 mechanism is positioned for early-stage, innovative, high-risk/high-reward, or concept-establishing projects that may not yet have extensive preliminary data.
Does the R21 award under this FOA require extensive preliminary data?
The announcement describes R21 projects as potentially not yet having extensive preliminary data, reflecting the exploratory/developmental nature of the mechanism.
Can this R21 be renewed?
No. A key feature noted for this mechanism is that it is not renewable.
How long can the project period be?
The project period can be up to two years.
What is the budget limit for direct costs over the project period?
Applicants may request up to $275,000 in total direct costs across the two-year period.
Is there a per-year direct cost cap?
Yes. The FOA specifies a cap of no more than $200,000 in direct costs in any single year.
Why is the award ceiling listed as $200,000 if the two-year total can be higher?
The information provided indicates the award ceiling is listed as $200,000, which aligns with the stated per-year direct cost cap, while the combined two-year direct cost total can be up to $275,000.
Can the final award size or duration differ from the stated limits?
Yes. The announcement notes that award size and duration can vary depending on the nature and scope of the proposed research.
How many awards will be made under this FOA?
The total number of awards and total dollars committed are described as depending on the quality, cost, and duration of applications received.
Who is eligible to apply?
Eligibility is broad and includes for-profit and nonprofit organizations and a wide range of public and private institutions. Examples referenced include universities, colleges, hospitals, laboratories, and units of state and local governments, as well as eligible federal agencies.
Are domestic and foreign institutions eligible?
Yes. The information provided states that both domestic and foreign institutions are eligible to apply.
What types of government entities are included as eligible applicants?
The eligibility listing includes multiple government entity types such as state, county, city/township, special districts, and independent school districts.
Are tribal organizations eligible to apply?
Yes. Tribal organizations are included, including federally recognized tribal governments and other Native American tribal organizations.
Who can serve as the Project Director/Principal Investigator (PD/PI)?
Any individual with the expertise, capability, and access to resources needed to carry out the project may apply through an eligible institution.
Does NIH encourage applications from underrepresented groups or individuals with disabilities?
Yes. NIH reiterates its standard encouragement for individuals from underrepresented racial and ethnic groups and individuals with disabilities to apply for support.
Can an applicant submit more than one application?
Yes. Applicants are allowed to submit more than one application as long as each submission is scientifically distinct.
Does this FOA replace an earlier announcement?
Yes. It replaces an earlier NIDCD program announcement on the same topic, indicating an updated solicitation under the NIH R21 mechanism.
Is cost sharing or matching required?
No cost sharing or matching requirement is stated in the provided information.
When was the FOA posted?
The FOA was posted on April 24, 2006.
What were the closing dates for this opportunity?
The original closing date was November 2, 2007, and a later current closing date was listed as July 16, 2009.
Is this FOA still active?
No. The archive date is August 17, 2009, which indicates it is no longer an active opportunity under this specific announcement.
What is the CFDA number associated with this opportunity?
The associated CFDA number is 93.173 (Research Related to Deafness and Communication Disorders).
Where were the official announcement details hosted?
The full official details were hosted on the NIH grants site (grants.nih.gov) per the information provided.
Who is listed as a contact for this FOA?
The contact information provided is for technical access and linking issues via the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, indicating the listed contact is primarily for web or announcement access rather than scientific or programmatic questions.
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