Opportunity Information: Apply for RFA AI 11 002
Apply for RFA AI 11 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (UM1)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Mar 29, 2011 and posted on Mar 29, 2011.
- Applicants must submit their applications by Sep 8, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $27,580,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $19,000,000.00 in funding.
- Eligible applicants include: County governments For profit organizations other than small businesses Special district governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education State governments City or township governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Public housing authorities/Indian housing authorities Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Organizations) are not eligible to apply. Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI ID) (UM1) funding opportunity, released by the National Institute of Allergy and Infectious Diseases (NIAID) within the National Institutes of Health (NIH), is a cooperative agreement solicitation aimed at creating a single, coordinated research Center devoted to accelerating HIV vaccine development. The core purpose is to bring together a multidisciplinary team that can tackle the major immunological barriers that have slowed progress toward a safe and effective HIV vaccine. Rather than supporting isolated projects, this FOA is designed to fund an integrated, multi-pronged program where different scientific disciplines and approaches are organized under one Center structure to drive discovery, translate findings into vaccine concepts, and systematically address the challenges unique to inducing protective immunity against HIV.
This opportunity uses the UM1 mechanism, which is a cooperative agreement, meaning NIH expects to have substantial involvement in the program beyond standard grant oversight. In practice, applicants should anticipate a more coordinated relationship with NIAID that often includes active scientific and programmatic collaboration, shared milestones, and structured management expectations typical of large center-based efforts. The activity category is health research, aligned with CFDA numbers 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research), reflecting the program's emphasis on both immunology and infectious disease biology as they relate to HIV vaccine discovery.
The posted date for the FOA was March 29, 2011, with an original and current closing date of September 8, 2011, and an archive date of October 9, 2011. The FOA listed an estimated total funding amount of $27,580,000, with an award ceiling of $19,000,000. No cost sharing or matching was required, which is consistent with many NIH research programs and helps ensure that scientific merit and capacity are the primary factors for competitiveness rather than an applicant's ability to contribute non-federal funds.
Eligibility was broad across U.S.-based organizations and governmental units, reflecting NIH's intent to allow the strongest possible applicants to compete for this Center award. Eligible applicants included public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with 501(c)(3) status and certain nonprofits without 501(c)(3) status), for-profit organizations other than small businesses, small businesses, and a wide range of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and regional organizations. The FOA also explicitly recognized eligibility for several mission-relevant institution types and community-anchored organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations, as well as Native American tribal governments and tribal organizations in multiple categories. U.S. territories or possessions were included as eligible applicants as well.
At the same time, the FOA set clear boundaries around foreign participation. Non-domestic (non-U.S.) entities (foreign organizations) were not eligible to apply as the primary applicant organization. However, foreign components of U.S. organizations were allowed, which typically means that a U.S.-based applicant could include an overseas site, collaboration, or performance component if justified scientifically and administratively within NIH policy.
Operationally, applicants were directed to the full announcement hosted on the NIH grants website (RFA-AI-11-002). The contact support listed in the source data focused on technical access issues through the NIH Office of Extramural Research (OER) webmaster email, which is common for ensuring applicants can retrieve or properly link to the complete FOA text and required application instructions. Overall, this opportunity was structured to fund a large, center-scale, team-science effort designed to remove key immunological roadblocks and speed the discovery and development pipeline for HIV vaccine candidates through coordinated immunology and immunogen discovery research.
FAQs: Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI ID) (UM1)
What is this funding opportunity?
This is a National Institutes of Health (NIH) funding opportunity from the National Institute of Allergy and Infectious Diseases (NIAID) to support the Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (CHAVI ID) using the UM1 cooperative agreement mechanism. It is a solicitation to create a single, coordinated research Center focused on accelerating HIV vaccine development.
What is the main goal of CHAVI ID?
The main goal is to accelerate HIV vaccine development by bringing together a multidisciplinary team to address major immunological barriers that have slowed progress toward a safe and effective HIV vaccine.
What makes this opportunity different from funding separate research projects?
Rather than supporting isolated projects, this opportunity is designed to fund an integrated, multi-pronged program organized under one Center structure. The expectation is that multiple disciplines and approaches will be coordinated to drive discovery, translate findings into vaccine concepts, and systematically tackle challenges specific to inducing protective immunity against HIV.
Which NIH institute is sponsoring this opportunity?
The opportunity was released by NIAID within NIH.
What is the funding mechanism, and what does it imply?
The mechanism is UM1, which is a cooperative agreement. This implies NIH expects substantial involvement beyond standard grant oversight, including a more coordinated relationship with NIAID that can involve active scientific and programmatic collaboration, shared milestones, and structured management expectations typical of large center-based programs.
What research area does this opportunity fall under?
The activity category is health research, with an emphasis on immunology and infectious disease biology as they relate to HIV vaccine discovery.
Which CFDA numbers are associated with this program?
The associated CFDA numbers are 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research).
What is the FOA identifier?
The full announcement is hosted on the NIH grants website under RFA-AI-11-002.
When was the opportunity posted, and what were the key dates?
The posted date was March 29, 2011. The original closing date and the current closing date were both September 8, 2011. The archive date was October 9, 2011.
How much funding was expected to be available?
The FOA listed an estimated total funding amount of $27,580,000.
What was the maximum award amount (award ceiling)?
The award ceiling listed was $19,000,000.
Is cost sharing or matching required?
No. The FOA stated that no cost sharing or matching was required.
Who is eligible to apply?
Eligibility was broad across U.S.-based organizations and governmental units. Eligible applicants included:
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status)
- For-profit organizations other than small businesses
- Small businesses
- Government entities (including state, county, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and regional organizations)
- U.S. territories or possessions
Are minority-serving institutions and community-based organizations eligible?
Yes. The FOA explicitly recognized eligibility for several institution types and community-anchored organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations.
Are tribal governments and tribal organizations eligible?
Yes. The FOA included Native American tribal governments and tribal organizations in multiple eligibility categories.
Can a foreign (non-U.S.) organization apply as the primary applicant?
No. Non-domestic (non-U.S.) entities (foreign organizations) were not eligible to apply as the primary applicant organization.
Can a U.S.-based applicant include a foreign component?
Yes. Foreign components of U.S. organizations were allowed, meaning a U.S.-based applicant could include an overseas site, collaboration, or performance component if scientifically and administratively justified within NIH policy.
How many Centers was this FOA designed to fund?
Based on the description provided, the solicitation aimed at creating a single, coordinated research Center.
What kind of program structure does NIH appear to be seeking?
The FOA is framed around a Center-scale, team-science structure with coordinated management, integrated research efforts across disciplines, and a systematic approach to overcoming immunological barriers to HIV vaccination.
Where can applicants find the complete announcement and instructions?
Applicants were directed to the full announcement hosted on the NIH grants website (RFA-AI-11-002).
Who is listed as a point of contact in the provided information?
The source data highlighted technical access support through the NIH Office of Extramural Research (OER) webmaster email, which is typically used for technical issues related to accessing the announcement and related web resources.
Does the provided information include scientific contacts or program officer details?
No. The information provided only mentions technical access support via the NIH OER webmaster and does not list scientific, grants management, or programmatic contacts.
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