Opportunity Information: Apply for MP CPI 26 002

  • The Office of the Assistant Secretary for Health in the health sector is offering a public funding opportunity titled "Center for Indigenous Innovation and Health" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.137.
  • This funding opportunity was created on 2026-06-15.
  • Applicants must submit their applications by 2026-07-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education.
Apply for MP CPI 26 002

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Opportunity Summary:

The Center for Indigenous Innovation and Health (CIIH) funding opportunity (MP CPI 26 002) is a discretionary federal grant program offered through the Office of the Assistant Secretary for Health. It will make up to four awards using a cooperative agreement mechanism, which generally means recipients should expect an ongoing, collaborative relationship with the federal project team during planning, implementation, and reporting. The program is designed to back practical, community-rooted work that reduces chronic disease burden and closes health care access gaps affecting Indigenous communities, specifically American Indian and Alaska Native (AI/AN) and Native Hawaiian and Pacific Islander (NHPI) populations.

At its core, CIIH is looking for projects that blend evidence-based frameworks with community-based strategies to prevent and improve chronic disease outcomes. The solicitation highlights obesity, hypertension, and diabetes, along with related conditions, as priority targets. Funded efforts can include research activities, education and training, direct services, partnership development, and technical assistance. The emphasis is not just on producing information, but on implementing approaches that are already supported by evidence and adapting them in culturally grounded ways so they work in real-world Indigenous settings.

A key structural requirement is that each funded project should concentrate on one Indigenous population of focus rather than trying to cover multiple populations at once. That focus is meant to support depth, sustained engagement, and more measurable health impact. Strong applications will typically show how the proposed strategies will be delivered in partnership with the community, how they will be tailored to cultural and local context, and how the project will track progress on both health outcomes and access-related barriers (for example, availability of preventive care, screening, care navigation, workforce capacity, or other factors driving gaps in care).

Eligibility is broad, as long as the applicant is a public entity or a private nonprofit located in an eligible U.S. jurisdiction. Eligible jurisdictions include the 50 states, Washington, DC, Puerto Rico, the U.S. Virgin Islands, the Commonwealth of the Northern Mariana Islands, American Samoa, Guam, and several Freely Associated States and territories listed in the notice: the Republic of Palau, the Federated States of Micronesia, and the Republic of the Marshall Islands. Eligible applicant types include state, county, and local governments; special districts; independent school districts; public and state-controlled institutions of higher education; federally recognized Tribal governments; Tribal organizations (including those not classified as federally recognized Tribal governments); public housing authorities and Indian housing authorities; and nonprofits both with and without 501(c)(3) status (excluding institutions of higher education when the nonprofit category is specified separately). The notice also makes clear that faith-based organizations are eligible if they meet the public or nonprofit requirement, and that public or nonprofit community-based organizations and nonprofit private institutions of higher education may apply.

Financially, the maximum award amount (award ceiling) is $1,000,000 per award, and the agency anticipates making four awards. The opportunity falls under CFDA 93.137 (Health). The application deadline listed is July 15, 2026. Overall, CIIH is positioned for organizations that can demonstrate trusted community partnerships, culturally responsive implementation capacity, and a clear plan for applying proven chronic disease prevention and management strategies in ways that improve outcomes and reduce access gaps for a specific Indigenous population.

Frequently Asked Questions (FAQs)

What is the Center for Indigenous Innovation and Health (CIIH) funding opportunity?

The Center for Indigenous Innovation and Health (CIIH) funding opportunity (MP CPI 26 002) is a discretionary federal grant program offered through the Office of the Assistant Secretary for Health. It is intended to support practical, community-rooted projects that reduce chronic disease burden and close health care access gaps affecting Indigenous communities.

What funding mechanism is being used for this opportunity?

This opportunity uses a cooperative agreement mechanism. In general, that means recipients should expect an ongoing, collaborative relationship with the federal project team during planning, implementation, and reporting.

How many awards are expected to be made?

The agency anticipates making up to four awards under this opportunity.

What is the maximum funding amount per award?

The award ceiling is $1,000,000 per award.

What is the purpose of the CIIH program?

The program is designed to back practical work that reduces chronic disease burden and addresses health care access gaps for Indigenous communities, specifically American Indian and Alaska Native (AI/AN) and Native Hawaiian and Pacific Islander (NHPI) populations.

Which populations are the focus of this grant program?

The funding opportunity specifically highlights Indigenous communities, including American Indian and Alaska Native (AI/AN) and Native Hawaiian and Pacific Islander (NHPI) populations.

Does each project need to focus on a single population?

Yes. A key structural requirement is that each funded project should concentrate on one Indigenous population of focus rather than attempting to cover multiple populations at once. The intent is to support depth of engagement and measurable impact.

What health issues are prioritized in this solicitation?

The solicitation highlights obesity, hypertension, and diabetes as priority targets, along with related conditions.

What kinds of activities can be supported with CIIH funding?

Funded efforts can include research activities, education and training, direct services, partnership development, and technical assistance.

Is this program focused on generating new information, or on implementation?

The emphasis is on implementing approaches that are already supported by evidence and adapting them in culturally grounded ways so they work in real-world Indigenous settings, rather than only producing information.

What does the opportunity mean by "evidence-based frameworks" and "community-based strategies"?

Based on the notice, CIIH is looking for projects that combine strategies supported by evidence with practical, community-rooted approaches. The goal is to apply proven methods while tailoring implementation to cultural and local context.

What makes an application "strong" for this opportunity?

Strong applications will typically explain how strategies will be delivered in partnership with the community, how they will be tailored to cultural and local context, and how the project will track progress on health outcomes and access-related barriers.

What kinds of access-related barriers does the program expect projects to address or measure?

Examples listed include availability of preventive care, screening, care navigation, workforce capacity, and other factors driving gaps in care.

Who is eligible to apply?

Eligibility is broad, as long as the applicant is a public entity or a private nonprofit located in an eligible U.S. jurisdiction.

Which jurisdictions are eligible under this funding opportunity?

Eligible jurisdictions include the 50 states, Washington, DC, Puerto Rico, the U.S. Virgin Islands, the Commonwealth of the Northern Mariana Islands, American Samoa, and Guam. The notice also lists the Republic of Palau, the Federated States of Micronesia, and the Republic of the Marshall Islands.

Are federally recognized Tribal governments eligible to apply?

Yes. Federally recognized Tribal governments are included among eligible applicant types.

Are Tribal organizations eligible even if they are not federally recognized Tribal governments?

Yes. The notice states that Tribal organizations are eligible, including those not classified as federally recognized Tribal governments.

Are state, county, or local governments eligible applicants?

Yes. State, county, and local governments are included among eligible applicant types.

Are schools and higher education institutions eligible?

Eligible applicant types include independent school districts and public and state-controlled institutions of higher education. The notice also indicates that nonprofit private institutions of higher education may apply.

Are nonprofits eligible to apply, including organizations without 501(c)(3) status?

Yes. Nonprofits both with and without 501(c)(3) status are listed as eligible applicant types (with an exclusion noted for institutions of higher education when the nonprofit category is specified separately).

Are faith-based organizations eligible?

Yes. The notice makes clear that faith-based organizations are eligible if they meet the public or nonprofit requirement.

Are public housing authorities or Indian housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities are included in the list of eligible applicant types.

What is the CFDA number associated with this opportunity?

The opportunity falls under CFDA 93.137 (Health).

When is the application deadline?

The application deadline listed is July 15, 2026.

What should applicants expect in terms of working with the federal project team?

Because this is a cooperative agreement, recipients should anticipate ongoing collaboration with the federal project team during planning, implementation, and reporting.

What overall capacities or characteristics does CIIH appear to prioritize?

CIIH is positioned for organizations that can demonstrate trusted community partnerships, culturally responsive implementation capacity, and a clear plan to apply proven chronic disease prevention and management strategies to improve outcomes and reduce access gaps for a specific Indigenous population.

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