Opportunity Information: Apply for PAR 14 207
Apply for PAR 14 207
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research.
- This funding opportunity was created on May 6, 2014 and posted on May 6, 2014.
- Applicants must submit their applications by Jul 1, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01) opportunity (Funding Opportunity Number PAR 14-207) is an NIH-wide program managed by the National Human Genome Research Institute (NHGRI) that gives researchers access to centralized, high-capacity genomic technologies and expertise. Rather than functioning like a traditional research grant that primarily provides money to run a project in the applicant's own lab, this X01 mechanism is designed to provide approved investigators with access to CIDR's specialized laboratory and analytical capabilities. The overall purpose is to speed up discovery of genes, variants, and other genetic changes that contribute to human health and disease by making advanced genotyping, sequencing, and statistical genetics support available to projects that can benefit from scale, standardization, and deep technical know-how.
CIDR's niche is handling genomic services that are difficult for individual investigator laboratories to perform efficiently on their own, particularly when studies require high throughput processing, rigorous quality control, or specialized platforms and pipelines. The resource supports large-scale genotyping and sequencing efforts and pairs the laboratory work with supporting statistical genetics services, which is especially important for studies where the value comes not just from generating data but from ensuring the data are produced, cleaned, and analyzed in ways that are reliable and comparable across studies. In practical terms, applicants propose projects where CIDR's current technology platforms and expert support can materially improve feasibility, quality, throughput, or cost-effectiveness compared with doing the work locally. Up-to-date information on the specific services and platforms available at the time of application is maintained by CIDR and can be found on their website (http://www.cidr.jhmi.edu), which applicants would use to understand what assays, sequencing approaches, and analytical support are currently offered.
The announcement is categorized as discretionary funding and uses the grant funding instrument type, with the activity category listed under health (CFDA 93.172, Human Genome Research). There is no cost sharing or matching requirement. Although it is an NIH opportunity, the program is structured as a resource access mechanism, meaning the emphasis is on eligibility and suitability for using the CIDR resource rather than providing unrestricted funds for any research expense. The administrative home is NIH, with NHGRI managing the initiative on behalf of NIH more broadly.
Eligibility is intentionally broad, reflecting the NIH-wide nature of the resource and the goal of enabling diverse institutions and research teams to use centralized genomic infrastructure. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, state governments, small businesses, for-profit organizations other than small businesses, and multiple types of nonprofit organizations (including those with 501(c)(3) status and certain nonprofits without 501(c)(3) status, other than institutions of higher education). The opportunity also explicitly includes Native American tribal governments (federally recognized) and Native American tribal organizations (other than federally recognized tribal governments). In addition, the eligibility language extends to a wide set of specialized institutional categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs). Importantly, non-U.S. entities are eligible as well: foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed, including U.S. territories or possessions. This broad eligibility is consistent with a shared-service model where the primary question is whether the proposed work aligns with CIDR's mission and capabilities and whether centralized processing will meaningfully advance the science.
Key dates in the record show the opportunity was posted and created on May 6, 2014, with an original closing date of July 1, 2017, and a current closing date also listed as July 1, 2017. The archive date is August 1, 2017, indicating the announcement is no longer active as originally posted and has been archived, although similar CIDR access opportunities may exist under newer announcements or updated NIH mechanisms. The authoritative program announcement link is provided through NIH's grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-14-207.html, which contains the full details, application instructions, and any NIH-specific policy requirements that applied during the open period.
For support issues related to accessing the full announcement or troubleshooting links, the contact provided is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV). For scientific or service-specific planning, applicants are directed in practice to consult CIDR's service descriptions and current capabilities via the CIDR site, since the exact platforms and offerings can evolve over time. Overall, the opportunity exists to remove technical and analytical bottlenecks in large-scale human genetics and genomics research by routing qualifying projects through a dedicated, high-throughput center with modern platforms and specialized statistical genetics support.
FAQs: CIDR High Throughput Sequencing and Genotyping Resource Access (X01) (PAR 14-207)
What is the CIDR High Throughput Sequencing and Genotyping Resource Access (X01) opportunity?
It is an NIH-wide program managed by the National Human Genome Research Institute (NHGRI) that provides approved researchers access to the Center for Inherited Disease Research (CIDR) high-capacity genomic technologies and expertise. The goal is to accelerate discovery of genes, variants, and other genetic changes that contribute to human health and disease by using centralized, high-throughput genotyping, sequencing, and supporting statistical genetics services.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is PAR 14-207, and it is described as the CIDR High Throughput Sequencing and Genotyping Resource Access (X01).
Who manages this program at NIH?
The program is managed by the National Human Genome Research Institute (NHGRI) on behalf of NIH more broadly.
Is this a traditional research grant that mainly provides funding to my lab?
No. This X01 mechanism is described as a resource access mechanism. Instead of primarily providing money to run the project in the applicant's own laboratory, it provides approved investigators access to CIDR's specialized laboratory and analytical capabilities.
What does "resource access" mean in practical terms for applicants?
Applicants propose projects where CIDR's current technology platforms and expert support can materially improve feasibility, quality, throughput, or cost-effectiveness compared with doing the work locally. The emphasis is on eligibility and suitability for using CIDR's resource rather than receiving unrestricted funds for general research expenses.
What kinds of work is CIDR designed to support?
CIDR focuses on genomic services that are difficult for individual investigator laboratories to perform efficiently on their own, especially when studies require high-throughput processing, rigorous quality control, or specialized platforms and pipelines. It supports large-scale genotyping and sequencing efforts and pairs the lab work with supporting statistical genetics services.
Why would a project use CIDR instead of performing the work in-house?
CIDR is intended for situations where centralized processing and expert support provide advantages such as scale, standardization, high throughput, rigorous quality control, and deep technical know-how. The program is positioned to reduce technical and analytical bottlenecks by routing qualifying projects through a dedicated center with modern platforms and specialized statistical genetics support.
Does the resource include support beyond generating sequencing or genotyping data?
Yes. The resource pairs laboratory work with supporting statistical genetics services, reflecting that value often comes from producing, cleaning, and analyzing data in reliable and comparable ways across studies.
Where can applicants find the current list of CIDR services and platforms?
Up-to-date information on specific services and platforms available at the time of application is maintained by CIDR and is available on the CIDR website: http://www.cidr.jhmi.edu.
What is the program purpose or overall scientific goal?
The overall purpose is to speed discovery of genes, variants, and other genetic changes relevant to human health and disease by making advanced genotyping, sequencing, and statistical genetics support available to projects that benefit from scale, standardization, and specialized expertise.
What type of funding category is this opportunity listed under?
The announcement is categorized as discretionary funding and uses the grant funding instrument type.
What is the activity category and CFDA number associated with this opportunity?
The activity category is listed under health, and the CFDA number is 93.172 (Human Genome Research).
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
Which organizations are eligible to apply?
Eligibility is broad and includes: public and state-controlled institutions of higher education; private institutions of higher education; state governments; small businesses; for-profit organizations other than small businesses; and multiple types of nonprofit organizations, including 501(c)(3) nonprofits and certain nonprofits without 501(c)(3) status (other than institutions of higher education).
Are tribal governments or tribal organizations eligible?
Yes. The eligibility language explicitly includes Native American tribal governments (federally recognized) and Native American tribal organizations (other than federally recognized tribal governments).
Are minority-serving institutions specifically included in eligibility?
Yes. The opportunity explicitly includes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions (AANAPISIs).
Can non-U.S. organizations apply?
Yes. Foreign organizations and foreign institutions may apply. Non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed, including U.S. territories or possessions.
Where is the full, authoritative announcement posted?
The authoritative program announcement is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-14-207.html.
When was this opportunity posted, and what were the key dates?
The record shows the opportunity was posted and created on May 6, 2014. The original closing date was July 1, 2017, and the current closing date is also listed as July 1, 2017. The archive date is August 1, 2017.
Is this funding opportunity still active?
Based on the listed closing date (July 1, 2017) and archive date (August 1, 2017), the announcement is no longer active as originally posted and has been archived. The information notes that similar CIDR access opportunities may exist under newer announcements or updated NIH mechanisms.
What should applicants do if they need help accessing the full announcement or have link issues?
For support related to accessing the full announcement or troubleshooting links, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Who should applicants consult for scientific or service-specific planning?
Applicants are directed in practice to consult CIDR's service descriptions and current capabilities via the CIDR website (http://www.cidr.jhmi.edu), because platforms and offerings can evolve over time.
What is the main reason NIH offers this kind of centralized resource?
The opportunity is intended to remove technical and analytical bottlenecks in large-scale human genetics and genomics research by providing access to a dedicated, high-throughput center with modern platforms and specialized statistical genetics support.
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