Opportunity Information: Apply for PAR 14 035

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Centers of Biomedical Research Excellence (COBRE) (P20)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
  • This funding opportunity was created on Dec 12, 2013 and posted on Dec 12, 2013.
  • Applicants must submit their applications by Jan 28, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
  • Eligible applicants include: Small businesses Special district governments Independent school districts County governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities For profit organizations other than small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Centers of Biomedical Research Excellence (COBRE) (P20) opportunity (Funding Opportunity Number PAR-14-035) is a National Institutes of Health (NIH) grant program administered by the National Institute of General Medical Sciences (NIGMS). It is designed to build and strengthen biomedical research capacity in states that are eligible for the Institutional Development Award (IDeA) Program, which focuses on improving the competitiveness of institutions and investigators in jurisdictions that have historically received lower levels of NIH funding. In practical terms, COBRE is meant to help an institution move from having promising but limited research infrastructure to having a more mature, sustainable, and competitive research environment that can consistently attract external, peer-reviewed research support.

A central feature of COBRE is the creation or enhancement of a thematic, multidisciplinary research center at an eligible institution. Rather than funding unrelated projects, the program expects the center to have a unifying scientific theme that ties together multiple research efforts and encourages collaboration across departments, disciplines, and career stages. The center structure is intended to serve as a catalyst: it organizes people and resources around a shared scientific focus, supports research projects that fit the theme, and builds the kinds of shared facilities, expertise, and administrative support systems that make a research enterprise more productive and competitive over time.

The main objective is capacity-building with an emphasis on investigator development. COBRE aims to enhance the ability of investigators, particularly those who are developing their independent careers, to compete successfully for individual NIH research project grants and other external peer-reviewed funding. The program is structured to help investigators generate strong preliminary data, publish competitive findings, and position themselves for subsequent independent awards. At the institutional level, COBRE is about putting durable research infrastructure in place, so that improvements remain after the award ends and continue to benefit future investigators.

This opportunity falls under the discretionary category and uses a grant funding instrument, with an activity category focused on health. The CFDA listing associated with this program is 93.859 (Biomedical Research and Research Training). The announcement indicates there is no cost sharing or matching requirement, which means applicants are not required to provide matching funds as a condition of the award (though institutions often still demonstrate commitment through space, hiring plans, or other support in their applications).

The maximum listed award amount (award ceiling) is $1,500,000, reflecting the program’s emphasis on substantial infrastructure and research capacity development rather than small, project-limited support. Key dates in the posted record show the opportunity was posted and created on December 12, 2013, with an original and current closing date of January 28, 2016, and an archive date of February 28, 2016. That timeline indicates this specific announcement is now archived, but it remains a useful reference for the structure and goals of COBRE as a program mechanism.

Eligibility is broad across many U.S.-based organization types, as long as the applicant is an appropriate institution within an IDeA-eligible state and meets the program’s specific institutional expectations (notably, biomedical research institutions that award doctoral degrees in health sciences or health-related sciences, or independent biomedical research institutes in those jurisdictions). The eligible applicant categories listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and a range of government entities (state, county, city/township, special district governments), as well as public housing authorities/Indian housing authorities. The eligibility text also highlights additional eligible applicants such as Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), among others. Regional organizations, faith-based or community-based organizations, and eligible federal government agencies are also mentioned in the eligibility language, reflecting NIH’s general approach of listing organizational types while still requiring alignment with the FOA’s specific program purpose and institutional context.

Foreign participation is explicitly restricted. Non-U.S. (foreign) entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as NIH defines them in its Grants Policy Statement) are not allowed. In effect, the center and its activities must be fully based within eligible U.S. jurisdictions and institutions, consistent with IDeA’s goal of strengthening research competitiveness in specific U.S. states and territories.

For applicants and stakeholders who want the full program requirements, the official announcement is linked through NIH at http://grants.nih.gov/grants/guide/pa-files/PAR-14-035.html. For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

COBRE (P20) Program (PAR-14-035) FAQs

What is the COBRE (P20) opportunity (PAR-14-035)?

The Centers of Biomedical Research Excellence (COBRE) (P20) opportunity (Funding Opportunity Number PAR-14-035) is an NIH grant program administered by the National Institute of General Medical Sciences (NIGMS). It is designed to build and strengthen biomedical research capacity at eligible institutions in states and jurisdictions that qualify for the NIH Institutional Development Award (IDeA) Program.

Which NIH institute administers this program?

This program is administered by the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH).

What is the purpose of COBRE?

COBRE is a capacity-building program aimed at helping institutions in IDeA-eligible jurisdictions develop more mature, sustainable, and competitive biomedical research environments. A major emphasis is building research infrastructure and developing investigators so they can compete successfully for external, peer-reviewed research support, including individual NIH research project grants.

How does COBRE build research capacity in practice?

COBRE supports the creation or enhancement of a thematic, multidisciplinary research center. The center organizes investigators and resources around a shared scientific theme, supports research projects aligned with that theme, encourages collaboration across departments and disciplines, and strengthens shared facilities, expertise, and administrative support to improve long-term competitiveness.

Does COBRE fund unrelated research projects?

No. COBRE is intended to support a center with a unifying scientific theme. Projects and activities are expected to fit within that theme and contribute to building a coherent, collaborative research environment.

What is meant by a "thematic, multidisciplinary research center" in COBRE?

In this context, a thematic, multidisciplinary center is a structured program within an institution where multiple research efforts are tied together by a shared scientific focus and designed to promote collaboration across disciplines and career stages, supported by shared resources and coordinated administration.

Is investigator development a central goal of COBRE?

Yes. A core objective is investigator development, particularly supporting investigators who are developing their independent careers. COBRE is structured to help them generate preliminary data, publish competitive findings, and become well-positioned to secure subsequent independent awards and other peer-reviewed external funding.

What does COBRE aim to leave behind after the award ends?

Beyond supporting research activities during the award period, COBRE aims to establish durable research infrastructure and systems so that institutional improvements remain in place and continue benefiting future investigators after the award ends.

What type of funding mechanism is used for this opportunity?

The opportunity uses a grant funding instrument and is listed under a discretionary funding category, with an activity category focused on health.

What is the CFDA number associated with this program?

The CFDA listing associated with this program is 93.859 (Biomedical Research and Research Training).

Is cost sharing or matching required?

No. The announcement indicates there is no cost sharing or matching requirement. Applicants are not required to provide matching funds as a condition of the award.

What is the maximum award amount listed for this opportunity?

The maximum listed award amount (award ceiling) is $1,500,000.

Is this specific funding opportunity still open?

No. The posted record indicates an original and current closing date of January 28, 2016, with an archive date of February 28, 2016. This means the specific announcement PAR-14-035 is archived.

Why would an archived FOA still be useful?

Even though PAR-14-035 is archived, it remains a useful reference for understanding the structure, goals, and general expectations of COBRE as a program mechanism focused on building research capacity and developing investigators within IDeA-eligible jurisdictions.

Who is eligible to apply for COBRE under this opportunity?

Eligibility is broad across many U.S.-based organization types, as long as the applicant is an appropriate institution within an IDeA-eligible state or jurisdiction and meets the program’s specific institutional expectations. The eligibility language references biomedical research institutions that award doctoral degrees in health sciences or health-related sciences, as well as independent biomedical research institutes in eligible jurisdictions.

What types of organizations are listed as eligible applicants?

The eligible applicant categories listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and various government entities (state, county, city/township, and special district governments), as well as public housing authorities/Indian housing authorities.

Are minority-serving institutions included in the eligibility language?

Yes. The eligibility text highlights categories such as Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), among others.

Are regional, faith-based, or community-based organizations mentioned as eligible?

Yes. The eligibility language also mentions regional organizations as well as faith-based or community-based organizations, consistent with NIH’s broad organizational type listings, while still requiring alignment with the FOA’s purpose and institutional context.

Can federal government agencies apply?

The eligibility language mentions eligible federal government agencies among the listed applicant categories, subject to meeting the FOA’s specific requirements and alignment with the program’s purpose.

Are foreign (non-U.S.) organizations allowed to apply?

No. Foreign participation is explicitly restricted. Non-U.S. (foreign) entities are not eligible to apply.

Can a U.S. organization include a non-U.S. component in the application?

No. Non-U.S. components of U.S. organizations are not eligible under this opportunity.

Are foreign components allowed in any form?

No. Foreign components (as NIH defines them in the NIH Grants Policy Statement) are not allowed.

Where can applicants find the official FOA details?

The official announcement is available through NIH at: http://grants.nih.gov/grants/guide/pa-files/PAR-14-035.html

Who should be contacted for technical issues accessing the announcement link?

For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What key dates are associated with this opportunity record?

The opportunity record shows it was posted and created on December 12, 2013. The closing date shown is January 28, 2016 (original and current), and the archive date is February 28, 2016.

What does it mean that the program targets IDeA-eligible states and jurisdictions?

It means COBRE is aimed at institutions located in states and jurisdictions that qualify for the NIH IDeA Program, which focuses on improving the competitiveness of institutions and investigators in areas that have historically received lower levels of NIH funding.

What is the overall institutional impact COBRE is intended to have?

COBRE is intended to help an institution move from promising but limited research infrastructure toward a mature and sustainable research environment that is more competitive and able to consistently attract external, peer-reviewed research support.

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