Opportunity Information: Apply for PAR 11 286

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Centers of Biomedical Research Excellence (COBRE) (P20)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.389 National Center for Research Resources 93.859 Biomedical Research and Research Training.
  • This funding opportunity was created on Dec 12, 2013 and posted on Aug 1, 2011.
  • Applicants must submit their applications by Dec 12, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $300,000.00 in funding.
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Apply for PAR 11 286

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Opportunity Summary:

The Centers of Biomedical Research Excellence (COBRE) (P20) opportunity (Funding Opportunity Number PAR 11-286) is a National Institutes of Health (NIH) grant program originally administered through the National Center for Research Resources (NCRR) and supported by the Institutional Development Award (IDeA) Program. Its central purpose is to help research institutions in IDeA-eligible states build stronger, more competitive biomedical research environments. The program is designed around the idea that long-term competitiveness comes from investing in people, shared resources, and a clear scientific focus, so COBRE funds are used to establish a thematic, multi-disciplinary research center that can serve as a platform for future growth.

A key goal of COBRE is infrastructure strengthening in a practical, institution-building sense. Rather than simply funding isolated projects, the program supports the development of an organized center built around a defined research theme. That theme provides a unifying structure for multiple investigators and encourages collaboration across disciplines. By doing this, COBRE aims to expand an institution's capacity to conduct high-quality biomedical research, including the underlying support systems that make research programs durable, such as shared facilities, coordinated administration, and a culture of mentorship and collaboration.

Another major objective is investigator development and improved competitiveness for external funding. COBRE is explicitly meant to position participating researchers to successfully compete for independent, peer-reviewed research support, especially NIH individual research awards and other comparable external grants. In other words, the COBRE center is intended to function as a launchpad: it helps investigators generate preliminary data, refine research directions, and integrate into a stronger scientific environment so they can later secure independent funding and sustain their work beyond the COBRE award period.

The opportunity targets institutions located in states that have historically received relatively low levels of NIH funding, which is the core focus of the IDeA Program. By concentrating support in these regions, COBRE works to reduce geographic disparities in biomedical research capacity and to broaden the national research base. Eligible applicant organizations include public or state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including those with and without 501(c)(3) status), provided they meet the program's location and institutional criteria. The announcement also notes eligibility for several institution types often emphasized in federal capacity-building efforts, including Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Hispanic-Serving Institutions, and Alaska Native and Native Hawaiian Serving Institutions, as long as they otherwise fit the program requirements.

Foreign participation is not allowed under this announcement. Non-U.S. (foreign) institutions may not apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not permitted. This keeps the program squarely focused on strengthening U.S.-based biomedical research capacity in the specific states targeted by the IDeA program.

From an administrative standpoint, the opportunity is a discretionary grant using the P20 mechanism, categorized under education and health-related funding activities. The CFDA numbers listed are 93.389 (National Center for Research Resources) and 93.859 (Biomedical Research and Research Training). The opportunity indicates no cost sharing or matching requirement. The source record lists an award ceiling of $300,000, along with key timeline fields (posted August 1, 2011; original closing date February 21, 2014; archive date January 12, 2014), reflecting that this particular posting is now historical/archived rather than an open competition. The full announcement was linked through the NIH grants policy/guide site under PAR 11-286, and the NIH Office of Extramural Research (OER) webmaster contact was provided for access or technical issues.

Frequently Asked Questions (FAQs) - Centers of Biomedical Research Excellence (COBRE) (P20) - PAR 11-286

What is the COBRE (P20) grant opportunity (PAR 11-286)?

The Centers of Biomedical Research Excellence (COBRE) (P20) opportunity (Funding Opportunity Number PAR 11-286) is a National Institutes of Health (NIH) grant program originally administered through the National Center for Research Resources (NCRR) and supported by the Institutional Development Award (IDeA) Program. It is designed to help research institutions in IDeA-eligible states strengthen their biomedical research environments and long-term competitiveness.

What is the main purpose of the COBRE program?

The central purpose is to build stronger, more competitive biomedical research environments at eligible institutions. COBRE emphasizes long-term competitiveness by investing in people (investigators), shared resources (core facilities), and a clear scientific focus (a defined research theme) through a structured, thematic research center.

How does COBRE differ from funding isolated research projects?

Rather than supporting disconnected individual projects, COBRE supports the development of an organized, thematic, multi-disciplinary research center. The center structure is intended to strengthen institutional research capacity by coordinating research efforts around a unifying theme and supporting the systems that make research programs durable (shared facilities, administration, and mentorship).

What does COBRE mean by a "thematic, multi-disciplinary research center"?

It refers to a center organized around a defined research theme that provides a unifying structure for multiple investigators and encourages collaboration across disciplines. The theme helps align people, resources, and research activities to build a coherent platform for institutional growth.

What kinds of institutional capacity or infrastructure does COBRE aim to strengthen?

COBRE aims to strengthen practical, institution-building infrastructure that supports high-quality biomedical research. Based on the opportunity description, this includes shared facilities (core resources), coordinated administration, and fostering a culture of mentorship and collaboration that supports sustainable research programs.

Is investigator development a goal of COBRE?

Yes. A major objective is investigator development and improving competitiveness for external funding. The COBRE center is intended to help participating researchers generate preliminary data, refine research directions, and operate within a stronger scientific environment so they can later compete successfully for independent, peer-reviewed support.

What types of future funding is COBRE intended to help investigators compete for?

The opportunity states that COBRE is meant to position researchers to compete for independent, peer-reviewed research support, especially NIH individual research awards and other comparable external grants.

Why does COBRE focus on IDeA-eligible states?

The program targets institutions in states that historically have received relatively low levels of NIH funding, which is the core focus of the IDeA Program. By concentrating support in these regions, COBRE aims to reduce geographic disparities in biomedical research capacity and broaden the national research base.

Who can apply for this opportunity?

Eligible applicant organizations include public or state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including those with and without 501(c)(3) status), provided they meet the program's location and institutional criteria tied to the IDeA Program.

Are certain institution types specifically noted as eligible?

Yes. The announcement notes eligibility for several institution types commonly emphasized in federal capacity-building efforts, including Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Hispanic-Serving Institutions, and Alaska Native and Native Hawaiian Serving Institutions, as long as they otherwise meet the program requirements.

Are foreign institutions allowed to apply?

No. Foreign participation is not allowed under this announcement. Non-U.S. (foreign) institutions may not apply.

Can a U.S. organization apply if it has a non-U.S. component?

No. The opportunity states that non-U.S. components of U.S. organizations are not eligible.

Are foreign components (as defined by NIH policy) permitted in this program?

No. The announcement states that foreign components (as defined by NIH policy) are not permitted.

What grant mechanism does COBRE use in this opportunity?

This opportunity uses the P20 mechanism and is described as a discretionary grant.

What general funding activity category is associated with this opportunity?

The opportunity is categorized under education and health-related funding activities.

What CFDA numbers are associated with this opportunity?

The CFDA numbers listed are 93.389 (National Center for Research Resources) and 93.859 (Biomedical Research and Research Training).

Is cost sharing or matching required?

No. The opportunity indicates there is no cost sharing or matching requirement.

What is the award ceiling listed in the source record?

The source record lists an award ceiling of $300,000.

Is this opportunity currently open?

No. The timeline information provided indicates this posting is historical/archived rather than an open competition (posted August 1, 2011; original closing date February 21, 2014; archive date January 12, 2014).

Where was the full announcement hosted or linked?

The full announcement was linked through the NIH grants policy/guide site under PAR 11-286.

Who is listed as a contact for access or technical issues?

The NIH Office of Extramural Research (OER) webmaster contact was provided for access or technical issues related to the announcement.

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