Opportunity Information: Apply for PAR 10 202
Apply for PAR 10 202
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Centers of Excellence in Genomic Science (CEGS) (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.242 Mental Health Research Grants.
- This funding opportunity was created on May 20, 2010 and posted on May 20, 2010.
- Applicants must submit their applications by May 25, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Eligible Agencies of the Federal Government.
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Opportunity Summary:
The Centers of Excellence in Genomic Science (CEGS) (P50) funding opportunity (PAR-10-202) is an NIH program designed to build and support academic Centers that push the boundaries of genome research. The core idea is to fund large, multi-investigator, interdisciplinary teams that can take on ambitious genomic challenges where the potential scientific payoff is very high, even if the work carries substantial risk. Rather than supporting incremental projects, CEGS Centers are expected to tackle a critical problem in genomic science and propose a path to a solution that would represent a major advance for the field.
A defining feature of a CEGS Center is its emphasis on innovation in genomic approaches. This can take several forms: developing new technologies for generating comprehensive genomic data sets, creating or advancing computational methods for analyzing large-scale genomic data, addressing a specific genome-scale biological problem, or otherwise inventing and applying genomic strategies that improve how biological systems are understood. In practice, this means proposed Centers should be able to justify why their chosen problem or method is both significant and uniquely suited to a Center-level, team-based effort, and why the approach is bold enough to move the field forward rather than simply extend existing techniques.
The FOA uses the Specialized Center (P50) grant mechanism, which is meant for coordinated research programs that bring multiple projects and shared goals together under a single Center structure. The expectation is that applicants will present not only excellent science, but also strong organizational and management plans, because the program explicitly balances higher-risk research with the need for outstanding planning, leadership, and coordination. Alongside the research mission, each Center is also expected to strengthen genomic science at its home institution by actively fostering cross-disciplinary collaboration and by training new investigators, with the broader goal of expanding the pipeline of professional genomics scientists and engineers.
An important administrative requirement is that applicants must submit a parallel application to the Initiative to Maximize Research Education in Genomics (R25) (referenced in the announcement as PAR-09-245). This requirement underscores that CEGS is not just about producing discoveries or tools, but also about building educational and workforce capacity in genomics at the institutional level.
The opportunity is sponsored by the National Institutes of Health, with involvement from the National Human Genome Research Institute (NHGRI) and the National Institute of Mental Health (NIMH), and it aligns with CFDA program areas 93.172 (Human Genome Research) and 93.242 (Mental Health Research Grants). There is no cost-sharing or matching requirement. NIH anticipated supporting about ten active CEGS P50 projects at any given time, with award size and project duration varying depending on the scope, quality, and cost structure of the applications received. Ultimately, both the number of awards and total dollars committed would be driven by the strength and feasibility of the top-ranked proposals.
Eligibility spans a range of organization types, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with and without 501(c)(3) status, other than institutions of higher education), and certain eligible federal agencies, as detailed in the full announcement. The FOA was posted May 20, 2010, with an original and final closing date of May 25, 2012, and it was archived June 25, 2012. For full details, NIH directed applicants to the official announcement link and provided NIH Office of Extramural Research (OER) webmaster contacts for access or technical issues.
Frequently Asked Questions (FAQs): Centers of Excellence in Genomic Science (CEGS) (P50) - PAR-10-202
What is the CEGS (P50) funding opportunity (PAR-10-202)?
The Centers of Excellence in Genomic Science (CEGS) (P50) opportunity (PAR-10-202) is an NIH program designed to build and support academic Centers that push the boundaries of genome research. It supports large, multi-investigator, interdisciplinary teams that pursue ambitious, high-payoff genomic challenges, including projects with substantial scientific risk.
What kind of work is CEGS intended to support?
CEGS Centers are expected to tackle a critical problem in genomic science and propose a path to a solution that would represent a major advance for the field. The program emphasizes bold approaches rather than incremental extensions of existing work.
What makes a project appropriate for a CEGS Center rather than a smaller grant?
Based on the announcement description, a CEGS project should be significant and uniquely suited to a Center-level, team-based effort. Applicants are expected to justify why the problem or method requires coordinated, multi-investigator collaboration and why the approach is innovative enough to move the field forward.
What does "high-risk, high-reward" mean in the context of this FOA?
The FOA is designed to support ambitious genomic science where the potential scientific payoff is very high, even if the work carries substantial risk. The program balances this higher-risk research emphasis with expectations for strong planning, leadership, and coordination.
What types of innovation does the FOA highlight for CEGS Centers?
The announcement describes innovation in genomic approaches in several forms, including: developing new technologies to generate comprehensive genomic data sets; creating or advancing computational methods for analyzing large-scale genomic data; addressing a specific genome-scale biological problem; or inventing and applying genomic strategies that improve how biological systems are understood.
What grant mechanism is used for CEGS awards?
The FOA uses the Specialized Center (P50) grant mechanism, intended for coordinated research programs that bring multiple projects and shared goals together under a single Center structure.
What organizational expectations are described for a CEGS Center?
In addition to excellent science, the program expects strong organizational and management plans. The FOA explicitly emphasizes leadership and coordination as key components, reflecting the complexity of a multi-project, team-based Center.
Does CEGS include training or workforce development expectations?
Yes. Each Center is expected to strengthen genomic science at its home institution by fostering cross-disciplinary collaboration and by training new investigators, with the broader goal of expanding the pipeline of professional genomics scientists and engineers.
Is there an additional application requirement related to education?
Yes. Applicants must submit a parallel application to the Initiative to Maximize Research Education in Genomics (R25), referenced as PAR-09-245 in the announcement. This requirement reinforces that the program is intended to build both research capacity and educational/workforce capacity in genomics.
Which NIH institutes are involved in this opportunity?
The opportunity is sponsored by the National Institutes of Health (NIH), with involvement from the National Human Genome Research Institute (NHGRI) and the National Institute of Mental Health (NIMH).
What CFDA program areas does this opportunity align with?
The announcement aligns with CFDA program areas 93.172 (Human Genome Research) and 93.242 (Mental Health Research Grants).
Is cost sharing or matching required?
No. The announcement states there is no cost-sharing or matching requirement.
How many awards did NIH anticipate making under this program?
NIH anticipated supporting about ten active CEGS P50 projects at any given time, according to the announcement summary provided.
Are award size and project duration fixed?
No. The announcement indicates that award size and project duration may vary depending on the scope, quality, and cost structure of the applications received.
What determines the number of awards and total funding committed?
The FOA indicates that both the number of awards and total dollars committed would be driven by the strength and feasibility of the top-ranked proposals.
Who is eligible to apply?
Eligibility includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with and without 501(c)(3) status, other than institutions of higher education), and certain eligible federal agencies, as described in the full announcement.
When was this FOA posted and when did it close?
The FOA was posted on May 20, 2010. The original and final closing date was May 25, 2012.
Is this opportunity still active?
No. The FOA was archived on June 25, 2012.
Where were applicants directed for official details and help with access issues?
NIH directed applicants to the official announcement link for full details and provided NIH Office of Extramural Research (OER) webmaster contacts for access or technical issues.
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