Opportunity Information: Apply for PAR 13 198

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Centers of Excellence in Genomic Science (CEGS) (P50)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Apr 12, 2013 and posted on Apr 12, 2013.
  • Applicants must submit their applications by Jul 8, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public housing authorities/Indian housing authorities For profit organizations other than small businesses Special district governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Public and State controlled institutions of higher education State governments Native American tribal governments (Federally recognized) City or township governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply for PAR 13 198

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Opportunity Summary:

The Centers of Excellence in Genomic Science (CEGS) (P50) opportunity, funded by the National Institutes of Health (NIH), is designed to establish and support academic Centers that can push the boundaries of genome research through bold, high-impact work. The core idea is to fund a coordinated, multi-investigator and interdisciplinary team that can develop and apply innovative genomic approaches to tackle a clearly defined biomedical problem. These Centers are meant to take on questions or barriers in genomic science or genomic medicine where solving the problem would represent a major leap forward, not an incremental improvement. Because of that, CEGS projects are expected to involve substantial scientific risk, but that risk has to be justified and balanced by exceptionally strong scientific rationale, a clear plan for execution, sound leadership and management structure, and a strong case for why the payoff could be transformative.

In terms of what a CEGS Center can focus on, the announcement emphasizes several broad but concrete directions. One major track is the development of novel technologies or computational methods that enable the production, integration, or analysis of comprehensive genomic-scale datasets. Another track is using genome-scale approaches to address a specific biomedical problem in a deep, systematic way, potentially integrating multiple data types or analytic strategies. The program is also open to other inventive ways of developing and using genomic approaches to understand biological systems, as long as the proposal is clearly centered on genomic science and has the potential to create a substantial advance for the field or for genomic medicine.

Beyond the research itself, the CEGS program is also structured to strengthen genomic science capacity within the funded institution. A key expectation is that the Center will serve as a hub that encourages meaningful collaboration across disciplines (for example, genomics, computational biology, engineering, statistics, clinical research, and related areas). Training is also an explicit priority: by providing training opportunities to new investigators, the Center is expected to help expand the pipeline of genomics scientists and engineers, building long-term expertise and workforce development rather than only producing a single set of research outcomes.

A notable administrative requirement is that applicants to the CEGS program must submit a parallel application tied to the Limited Competition Initiative to Maximize Research Education in Genomics (R25) Diversity Action Plan (referenced in the notice as PAR-13-063). In practice, this means a CEGS application is not intended to stand alone; the program is pairing Center-level research support with a structured effort focused on research education and diversity-related planning in genomics. Applicants would need to account for this linked submission in their overall proposal strategy and timelines.

The funding announcement is identified as PAR-13-198, categorized as a discretionary grant opportunity with a health-related funding activity focus. It is associated with CFDA numbers 93.172 (Human Genome Research) and 93.242 (Mental Health Research Grants). The opportunity does not require cost sharing or matching. Key dates listed include a posted and created date of April 12, 2013, an original and current closing date of July 8, 2013, and an archive date of August 8, 2013, indicating this specific announcement cycle is historical rather than currently open.

Eligibility is broad across many U.S.-based organization types, including public and private institutions of higher education, state and local governments, tribal governments and tribal organizations, nonprofits (with or without 501(c)(3) status), small businesses, and certain for-profit entities (other than small businesses), along with various special district and regional organizations. The eligibility section also explicitly calls out categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, Asian American and Native American Pacific Islander-serving institutions, faith-based or community-based organizations, and U.S. territories or possessions. At the same time, non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations are not eligible to apply, although foreign components (as defined under NIH policy) may be allowed, which typically means certain elements of a project may occur abroad under an eligible U.S. applicant organization when justified and compliant with NIH policy.

For those needing the official announcement details, NIH provided an additional information link to the full funding opportunity text (PAR-13-198) and listed contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.

Frequently Asked Questions (FAQs): Centers of Excellence in Genomic Science (CEGS) (P50) - PAR-13-198

What is the CEGS (P50) funding opportunity?

The Centers of Excellence in Genomic Science (CEGS) (P50) opportunity is a National Institutes of Health (NIH) program intended to establish and support academic Centers that push the boundaries of genome research through bold, high-impact work. It funds coordinated, multi-investigator, interdisciplinary teams that develop and apply innovative genomic approaches to address a clearly defined biomedical problem.

What is the main goal of a CEGS Center?

The main goal is to enable transformative advances in genomic science or genomic medicine by tackling major questions or barriers where success would represent a major leap forward rather than an incremental improvement.

What type of research does the program prioritize?

The announcement emphasizes research that is clearly centered on genomic science and has the potential for substantial advances. Examples of directions highlighted include developing novel technologies or computational methods for producing, integrating, or analyzing comprehensive genomic-scale datasets, and using genome-scale approaches to address a specific biomedical problem in a deep, systematic way.

Does the program support technology development and computational method development?

Yes. One major track described in the announcement is the development of novel technologies or computational methods that enable the production, integration, or analysis of comprehensive genomic-scale datasets.

Can a Center focus on applying genome-scale approaches to a specific biomedical problem?

Yes. Another major track is applying genome-scale approaches to address a specific biomedical problem in a deep, systematic way, potentially integrating multiple data types or analytic strategies.

Are other genomic science approaches allowed if they do not fit neatly into the example tracks?

Yes. The program is open to other inventive ways of developing and using genomic approaches to understand biological systems, as long as the proposal is clearly centered on genomic science and has the potential to create a substantial advance for the field or genomic medicine.

Is high scientific risk acceptable under CEGS?

Yes. CEGS projects are expected to involve substantial scientific risk, but that risk must be justified and balanced by exceptionally strong scientific rationale, a clear plan for execution, sound leadership and management, and a strong case that the payoff could be transformative.

What does NIH mean by a "Center" in this program?

In this opportunity, a Center is a coordinated, multi-investigator and interdisciplinary team effort designed to pursue a unified, clearly defined biomedical problem using innovative genomic approaches, with leadership and management structures appropriate for a complex, collaborative program.

Is interdisciplinary collaboration a requirement?

Yes. A key expectation is that the Center serves as a hub that encourages meaningful collaboration across disciplines such as genomics, computational biology, engineering, statistics, clinical research, and related areas.

Does the opportunity include training expectations?

Yes. Training is an explicit priority. The Center is expected to provide training opportunities to new investigators to help expand the pipeline of genomics scientists and engineers and support long-term workforce development.

Is there a linked or required companion application?

Yes. Applicants must submit a parallel application tied to the Limited Competition Initiative to Maximize Research Education in Genomics (R25) Diversity Action Plan, referenced as PAR-13-063. The CEGS application is not intended to stand alone and is paired with a structured research education and diversity-related planning effort in genomics.

What is the funding announcement number for this opportunity?

The funding announcement is identified as PAR-13-198.

What type of grant is this?

It is categorized as a discretionary grant opportunity with a health-related funding activity focus, and it uses the P50 Center grant mechanism.

What CFDA numbers are associated with this opportunity?

The opportunity is associated with CFDA 93.172 (Human Genome Research) and 93.242 (Mental Health Research Grants).

Is cost sharing or matching required?

No. The opportunity does not require cost sharing or matching.

Is this funding opportunity currently open?

No. The key dates indicate this announcement cycle is historical rather than currently open, with an original and current closing date of July 8, 2013, and an archive date of August 8, 2013.

What were the key dates listed for this opportunity?

The opportunity lists a posted and created date of April 12, 2013, an original and current closing date of July 8, 2013, and an archive date of August 8, 2013.

What types of organizations are eligible to apply?

Eligibility is broad across many U.S.-based organization types, including public and private institutions of higher education, state and local governments, tribal governments and tribal organizations, nonprofits (with or without 501(c)(3) status), small businesses, and certain for-profit entities (other than small businesses), along with special district and regional organizations.

Are minority-serving institutions and other designated categories included in eligibility?

Yes. The eligibility section explicitly includes categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, Asian American and Native American Pacific Islander-serving institutions, faith-based or community-based organizations, and U.S. territories or possessions.

Can a non-U.S. (foreign) institution apply directly?

No. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations are not eligible to apply.

Are foreign components allowed in any form?

The announcement notes that foreign components (as defined under NIH policy) may be allowed. This typically means certain project elements may occur abroad under an eligible U.S. applicant organization when justified and compliant with NIH policy.

Where can applicants find the official full text of the announcement?

NIH provided an additional information link to the full funding opportunity text (PAR-13-198) for official details.

Who is listed as a support contact for access or linking issues?

NIH listed contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues related to the announcement.

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