Opportunity Information: Apply for RFA AR 11 002
Apply for RFA AR 11 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Centers of Research Translation (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.846 Arthritis, Musculoskeletal and Skin Diseases Research.
- This funding opportunity was created on Mar 7, 2011 and posted on Feb 3, 2010.
- Applicants must submit their applications by Sep 20, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $6,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- Eligible applicants include: Small businesses City or township governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments County governments Public and State controlled institutions of higher education Independent school districts Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Centers of Research Translation (CORT) (P50) funding opportunity (RFA-AR-11-002) is a National Institutes of Health grant program run through the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Its core goal is to support a tightly coordinated, disease-focused translational research center that connects basic science discoveries to human disease relevance within NIAMS mission areas, which include arthritis, musculoskeletal conditions, and skin diseases. Rather than funding a single standalone project, this mechanism is built around a unifying translational theme tied to a specific disease or disease area, with multiple interrelated projects designed to reinforce each other. The expectation is that the combined work of the projects creates synergy, meaning the center produces more meaningful translational progress than the same projects would if they were funded separately.
Two defining elements shape what NIAMS is looking for in a CORT. First, the program is explicitly oriented around disease-specific research translation, emphasizing the pathway from fundamental biology to clinical insight, human pathophysiology, and ultimately better ways to understand, prevent, diagnose, or treat disease. Second, applicants must put forward shared resources and a clear administrative structure that actively enables translation across the center. In practice, this means the CORT is not just a collection of experiments; it is an organized framework with leadership, management plans, and often core-like capabilities that help investigators integrate approaches, share data or specimens when appropriate, coordinate milestones, and keep the overall program focused on translational outcomes.
This is a discretionary grant program using the P50 center grant mechanism. The activity category is health, and it falls under CFDA 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research). The announcement listed an estimated total funding amount of about $6,000,000, with an award ceiling of $1,000,000. Cost sharing or matching was not required, which generally means applicants are not expected to provide non-federal funds as a condition of the award (though institutional support can still strengthen a proposal in terms of feasibility).
Eligibility was broad and included many types of U.S.-based organizations and governments. Eligible applicants included public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status (outside of higher education), small businesses, and for-profit organizations other than small businesses, along with a range of government entities such as city or township governments, county governments, special district governments, and state governments. It also included public housing authorities/Indian housing authorities, tribal organizations, and federally recognized tribal governments. Additional eligible categories highlighted in the notice included Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. Taken together, the eligibility language signals NIAMS was open to center applications from many institutional settings, as long as the team could credibly build an integrated translational program aligned with NIAMS priorities.
Key dates in the listing show the opportunity was posted February 3, 2010, with an original closing date of June 10, 2011, and a later current closing date of September 20, 2011. The archive date was October 21, 2011, indicating it is no longer open, but the summary is still useful as a reference for how NIAMS structures translational center programs and what it expects from a P50 CORT application.
For applicants seeking the original full announcement details, the notice pointed to the NIH Grants Guide page for RFA-AR-11-002 (http://grants.nih.gov/grants/guide/rfa-files/RFA-AR-11-002.html). The contact listed for access or linking problems was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs): NIAMS Centers of Research Translation (CORT) (P50) - RFA-AR-11-002
What is the CORT (P50) funding opportunity (RFA-AR-11-002)?
The Centers of Research Translation (CORT) (P50) opportunity (RFA-AR-11-002) is a National Institutes of Health (NIH) grant program run through the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). It supports a tightly coordinated, disease-focused translational research center rather than a single standalone project.
Which NIH institute runs this program?
This program is administered through NIAMS (National Institute of Arthritis and Musculoskeletal and Skin Diseases), under the NIH.
What is the main purpose of a CORT?
The core goal is to connect basic science discoveries to human disease relevance within NIAMS mission areas, with an emphasis on translational progress tied to a specific disease or disease area.
What does "translational" mean in the context of this center?
In this context, translational research emphasizes the pathway from fundamental biology to clinical insight and human pathophysiology, ultimately supporting better ways to understand, prevent, diagnose, or treat disease.
Is this grant intended to fund a single research project?
No. The CORT mechanism is built around a unifying translational theme with multiple interrelated projects designed to reinforce each other within an organized center structure.
What is meant by a "unifying translational theme"?
Applicants are expected to propose a cohesive, disease-focused theme that ties the center together. The center's projects should be interrelated and aligned to that disease or disease area, with translation to human disease relevance as the central focus.
What does NIAMS mean by "synergy" across projects?
Synergy means the combined set of projects within the center should produce more meaningful translational progress than the same projects would if they were funded separately, due to coordination, shared resources, and an integrated plan.
What are the defining elements NIAMS is looking for in a CORT?
Two defining elements are emphasized: (1) disease-specific research translation from basic science to clinical or human disease relevance, and (2) shared resources plus a clear administrative structure that enables and actively supports translation across the center.
Why is an administrative structure important for a CORT?
The CORT is expected to be an organized framework with leadership and management plans that support integration across projects. This includes coordinating milestones, enabling collaboration, and keeping the program focused on translational outcomes.
What kinds of shared resources are expected?
The description emphasizes shared resources and "core-like capabilities" that help investigators integrate approaches, share data or specimens when appropriate, coordinate milestones, and maintain a coherent translational direction for the center.
What grant mechanism is used for this opportunity?
This is a discretionary grant program using the NIH P50 center grant mechanism.
What is the activity category and CFDA number?
The activity category is health. The CFDA number is 93.846, titled "Arthritis, Musculoskeletal and Skin Diseases Research."
What NIAMS mission areas does this opportunity cover?
The mission areas cited include arthritis, musculoskeletal conditions, and skin diseases.
How much funding was estimated to be available under this listing?
The listing provided an estimated total funding amount of about $6,000,000.
What was the award ceiling?
The award ceiling listed was $1,000,000.
Is cost sharing or matching required?
No. Cost sharing or matching was not required, meaning applicants were not expected to provide non-federal funds as a condition of the award (although institutional support may still be helpful for feasibility).
Who was eligible to apply?
Eligibility was broad and included many U.S.-based organizations and government entities, including higher education institutions, nonprofits, small businesses, for-profits (other than small businesses), and various local, state, tribal, and other government-related entities.
Are public and private higher education institutions eligible?
Yes. Eligible applicants included public and state-controlled institutions of higher education as well as private institutions of higher education.
Are nonprofits eligible, including those without 501(c)(3) status?
Yes. Eligibility included nonprofits with and without 501(c)(3) status (outside of higher education).
Are small businesses eligible to apply?
Yes. Small businesses were listed among eligible applicant types.
Are for-profit organizations eligible to apply?
Yes. The eligibility list included for-profit organizations other than small businesses.
Are government entities eligible?
Yes. The listing included city or township governments, county governments, special district governments, and state governments.
Are tribal governments and tribal organizations eligible?
Yes. Eligibility included tribal organizations and federally recognized tribal governments.
Are U.S. territories or possessions eligible?
Yes. The eligibility list included U.S. territories or possessions.
Were any specific institution types highlighted as eligible?
Yes. The notice highlighted Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs) among eligible categories.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations were included in the eligibility language.
Are federal agencies eligible to apply?
Yes. The eligibility categories included eligible federal agencies.
When was the opportunity posted and when did it close?
The listing shows it was posted on February 3, 2010. It had an original closing date of June 10, 2011, and a later current closing date of September 20, 2011.
Is this funding opportunity still open?
No. The archive date was October 21, 2011, which indicates the opportunity is no longer open.
Where can applicants find the original full announcement?
The notice pointed to the NIH Grants Guide page for RFA-AR-11-002: http://grants.nih.gov/grants/guide/rfa-files/RFA-AR-11-002.html
Who should be contacted for access or linking problems with the announcement?
The contact listed for access or linking problems was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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