Opportunity Information: Apply for PA 16 314
Apply for PA 16 314
- The HHS-NIH11 in the health, income security and social services sector is offering a public funding opportunity titled "Characterization of the Adolescent Reproductive Transition (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865,.
- This funding opportunity was created on Jun 07, 2016 and posted on Jun 07, 2016.
- Applicants must submit their applications by Sep 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Characterization of the Adolescent Reproductive Transition (R01) funding opportunity (PA-16-314) is a National Institutes of Health (NIH) research grant announcement focused on improving scientific understanding of puberty and the broader trajectory of adolescent sexual development. It is designed to support strong, hypothesis-driven research that clarifies how typical (normative) reproductive maturation unfolds in both males and females, with an emphasis on generating foundational knowledge about the timing, sequence, and biological and developmental pathways that lead to reproductive competence. The announcement highlights that important gaps remain in the field and explicitly encourages the use of newer technologies, modern research tools, and innovative approaches to move beyond what is already known about pubertal development.
At its core, this FOA seeks studies that better characterize the adolescent reproductive transition as a process, rather than treating puberty as a single event. Projects are expected to deepen understanding of the normal range of developmental patterns, which can help the field distinguish typical variation from atypical development and can improve the scientific baseline used in future clinical, public health, and mechanistic research. While the announcement is not limited to any single method, it signals strong interest in research that can capture complex developmental change over time and that can take advantage of advances in measurement and analytic strategies to describe developmental trajectories more precisely.
The funding mechanism is an R01, meaning it supports full-scale, investigator-initiated research projects rather than small pilot studies. The opportunity falls under the U.S. Department of Health and Human Services umbrella, administered through NIH (listed as HHS-NIH11 in the source data). It is categorized as a discretionary grant program within the broad area of Health, Income Security, and Social Services, and it is associated with CFDA number 93.865.
Eligibility is broad and includes many types of organizations that commonly apply for NIH research funding. Eligible applicants include public and private institutions of higher education (including public/state-controlled and private universities), nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education when applying under those nonprofit categories), for-profit organizations (other than small businesses), small businesses, and a range of government entities such as state, county, and city/township governments as well as special district governments. The FOA also allows participation from Native American tribal governments (federally recognized) and Native American tribal organizations (not federally recognized tribal governments), along with public housing authorities/Indian housing authorities. The listing also notes an "Others" category with additional eligibility details referenced in the full announcement text.
In terms of timing and administrative details, the FOA was created and posted on June 7, 2016, and the listed closing date for the referenced cycle is September 7, 2019 (both the original and current closing dates match in the provided data). The source fields for award ceiling and expected number of awards are not specified in the excerpt provided, which typically means applicants would need to consult the full FOA and NIH institute/center funding policies for budget expectations, project period norms, and anticipated award volume.
Overall, PA-16-314 is aimed at advancing the science of adolescent reproductive development by supporting rigorous research that maps and explains normative pubertal and sexual maturation in ways that are more detailed, more mechanistically informative, and better aligned with modern scientific capabilities. The intended outcome is a stronger evidence base for understanding how reproductive capacity is established during adolescence, creating a clearer foundation for future work that may address deviations from typical development, related health outcomes, and opportunities for prevention or intervention.
FAQs: Characterization of the Adolescent Reproductive Transition (R01) (PA-16-314)
What is the funding opportunity?
The funding opportunity is the NIH research grant announcement titled Characterization of the Adolescent Reproductive Transition (R01), FOA number PA-16-314. It supports research to improve scientific understanding of puberty and the broader trajectory of adolescent sexual development.
Which agency is offering this grant?
This opportunity is offered under the U.S. Department of Health and Human Services and administered through the National Institutes of Health (NIH) (listed as HHS-NIH11 in the source data).
What is the main scientific focus of PA-16-314?
The main focus is to advance understanding of normative (typical) reproductive maturation during adolescence in both males and females, including the timing, sequence, and biological and developmental pathways that lead to reproductive competence.
What does the FOA mean by studying puberty as a "process" rather than a single event?
The FOA emphasizes that puberty should be characterized as a developmental transition over time, not a one-time milestone. Projects are expected to capture how reproductive and sexual maturation unfolds across adolescence, including patterns and trajectories that reflect normal variation.
What kinds of research approaches does the announcement encourage?
While not limited to a single method, the announcement explicitly encourages the use of newer technologies, modern research tools, and innovative approaches to move beyond what is already known. It also signals interest in approaches that can capture complex developmental change over time and use advances in measurement and analytic strategies to describe developmental trajectories more precisely.
Is this FOA focused on typical development or atypical development?
The stated emphasis is on typical (normative) reproductive maturation and clarifying the normal range of developmental patterns. The FOA notes that strengthening the baseline understanding of typical variation can help the field distinguish typical variation from atypical development in future work.
What is the funding mechanism and what does it imply?
The mechanism is an R01. Based on the provided description, this means it supports full-scale, investigator-initiated research projects rather than small pilot studies.
What is the intended outcome or impact of the research supported by this FOA?
The intended outcome is a stronger evidence base for understanding how reproductive capacity is established during adolescence. This foundational knowledge is meant to create a clearer platform for future clinical, public health, and mechanistic research, including future work that may address deviations from typical development, related health outcomes, and prevention or intervention opportunities.
What subject area or category is this grant associated with?
In the provided data, the opportunity is categorized as a discretionary grant program within the broad area of Health, Income Security, and Social Services.
What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA number 93.865.
Who is eligible to apply?
Eligibility is broad and includes:
- Public and private institutions of higher education (including public/state-controlled and private universities)
- Nonprofit organizations with or without 501(c)(3) status (when applying under those nonprofit categories and not as institutions of higher education)
- For-profit organizations (other than small businesses)
- Small businesses
- State governments
- County governments
- City or township governments
- Special district governments
- Native American tribal governments (federally recognized)
- Native American tribal organizations (not federally recognized tribal governments)
- Public housing authorities / Indian housing authorities
- Others (with additional eligibility details referenced in the full announcement text)
Are both male and female adolescent development within scope?
Yes. The FOA explicitly highlights the importance of clarifying how normative reproductive maturation unfolds in both males and females.
Does the excerpt specify an award ceiling or the expected number of awards?
No. In the provided excerpt, the source fields for the award ceiling and expected number of awards are not specified. The description indicates applicants would typically need to consult the full FOA and relevant NIH institute/center funding policies for budget expectations, project period norms, and anticipated award volume.
When was this funding opportunity posted?
The FOA was created and posted on June 7, 2016.
What is the listed closing date for the referenced cycle?
The listed closing date in the provided data is September 7, 2019 (the original and current closing dates match in the excerpt).
Is the FOA limited to one specific method or study design?
No. The provided description states it is not limited to any single method, while strongly emphasizing research that can describe developmental trajectories over time and make use of modern measurement and analytic strategies.
Why does the FOA emphasize "foundational knowledge"?
The FOA frames this research as foundational because improving the basic scientific description of normative pubertal and sexual maturation helps establish a clearer baseline for later studies. That baseline can support future clinical, public health, and mechanistic research by distinguishing typical variation from atypical development.
What kinds of gaps is this FOA trying to address?
The announcement notes that important gaps remain in understanding pubertal development and adolescent sexual maturation, and it encourages using newer technologies and innovative approaches to move beyond what is already known, particularly around timing, sequence, and pathways leading to reproductive competence.
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