Opportunity Information: Apply for RFA ES 12 001

  • The National Institutes of Health in the environment health sector is offering a public funding opportunity titled "Childrens Environmental Health and Disease Prevention Research Centers (P01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health.
  • This funding opportunity was created on Apr 6, 2012 and posted on Apr 5, 2012.
  • Applicants must submit their applications by Jul 17, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $12,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments County governments Public and State controlled institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Small businesses Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Childrens Environmental Health and Disease Prevention Research Centers (P01) funding opportunity (RFA ES 12 001) is a discretionary grant program jointly advanced by the National Institute of Environmental Health Sciences (NIEHS) and the U.S. Environmental Protection Agency (EPA). Its purpose is to fund a small number of multi-project research centers that bring together multiple disciplines to better understand how environmental factors affect childrens health and well-being, and to use that knowledge to prevent disease and promote healthier outcomes for children. The emphasis is on a true center-based structure rather than a single-project study, meaning applicants are expected to assemble integrated teams and projects that collectively address childrens environmental health questions in a coordinated way.

A central theme of the announcement is transdisciplinary research that bridges basic science, applied research, clinical perspectives, and public health practice. In practical terms, the funded centers are meant to connect mechanistic or laboratory-based insights (for example, how a chemical exposure influences developing organs or immune function) with real-world exposure scenarios and health outcomes in children, and then translate findings into strategies that can reduce risk, prevent illness, or promote healthier development. The FOA explicitly encourages strong links between disciplines, which signals that competitive applications would not simply place different experts side-by-side, but would demonstrate how the fields inform one another through shared aims, cross-cutting methods, and coordinated interpretation of results.

The research supported through these centers is expected to cover substantive areas of childrens health while maintaining clear and meaningful links to environmental exposures or environmental conditions. The announcement highlights innovation in both technologies and approaches, suggesting that applicants are encouraged to use emerging tools and methods relevant to exposure assessment, biomarkers, toxicology, epidemiology, data integration, or other modern research strategies that can strengthen causal inference or improve the ability to detect, quantify, and interpret environment-related health effects in children. The overall framing is prevention-oriented: the science is not only about documenting associations, but also about generating actionable knowledge that can inform interventions, risk reduction, or health promotion across diverse child populations.

From a funding and scale standpoint, the FOA anticipated about 7 awards with an estimated total funding level of $12,000,000. The activity category is environment and health, and the CFDA number listed is 93.113 (Environmental Health). There is no cost sharing or matching requirement, which generally means applicants are not required to contribute non-federal funds as a condition of the award. The opportunity was posted in early April 2012, with a closing date of July 17, 2012, and an archive date of August 17, 2012, indicating it is a historical announcement rather than a currently open competition.

Eligibility is broad across many domestic organization types and includes public and private institutions of higher education, state and local governments (including city or township, county, and special district governments), independent school districts, small businesses, for-profit organizations other than small businesses, public housing authorities/Indian housing authorities, and nonprofit organizations both with and without 501(c)(3) status (with certain distinctions noted for institutions of higher education). The FOA also specifies additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and various tribal organizations and governments, including federally recognized tribal governments. At the same time, the announcement is clear that non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply, although foreign components as defined in the NIH Grants Policy Statement are allowed, which typically refers to discrete parts of a project that may be conducted outside the U.S. under specific NIH policy conditions.

The administering agency is the National Institutes of Health, with NIEHS as the lead NIH institute listed alongside EPA as a partnering agency for the program. For applicants or interested parties seeking full details, the FOA provided an NIH grants web link to the complete announcement text, and it listed the NIH Office of Extramural Research (OER) webmaster contact for technical issues accessing or linking to the announcement.

Frequently Asked Questions (FAQs)

What is the name of this funding opportunity?

The opportunity is titled Childrens Environmental Health and Disease Prevention Research Centers (P01), identified as RFA ES 12 001.

What type of grant program is this?

This is a discretionary grant program designed to support a small number of funded awards through a competitive process.

Who advances or sponsors this program?

The program is jointly advanced by the National Institute of Environmental Health Sciences (NIEHS) and the U.S. Environmental Protection Agency (EPA).

Which agency administers the awards?

The administering agency is the National Institutes of Health (NIH), with NIEHS listed as the lead NIH institute and EPA as a partnering agency.

What is the purpose of the funding opportunity?

The purpose is to fund a small number of multi-project research centers that bring together multiple disciplines to improve understanding of how environmental factors affect childrens health and well-being, and to use that knowledge to prevent disease and promote healthier outcomes for children.

What does it mean that this is a center-based (multi-project) program?

The announcement emphasizes a true center-based structure rather than a single-project study. Applicants are expected to assemble integrated teams and multiple coordinated projects that collectively address childrens environmental health questions.

Is the program focused on transdisciplinary research?

Yes. A central theme is transdisciplinary research that bridges basic science, applied research, clinical perspectives, and public health practice. Competitive applications are expected to show real integration across disciplines, not just parallel work by separate experts.

What kinds of research connections are expected across disciplines?

The centers are meant to connect mechanistic or laboratory-based insights (for example, how chemical exposures influence developing organs or immune function) with real-world exposure scenarios and child health outcomes, and then translate findings into prevention and risk-reduction strategies.

What topic area does this opportunity support?

The activity category is environment and health, with a focus on childrens environmental health and disease prevention.

How strongly must projects relate to environmental exposures?

Supported research is expected to cover substantive areas of childrens health while maintaining clear and meaningful links to environmental exposures or environmental conditions.

Does the announcement encourage innovation and new methods?

Yes. The announcement highlights innovation in both technologies and approaches, encouraging the use of emerging tools and methods relevant to areas such as exposure assessment, biomarkers, toxicology, epidemiology, and data integration.

Is the overall approach prevention-oriented?

Yes. The framing is explicitly prevention-oriented. The goal is not only to document associations, but to generate actionable knowledge that can inform interventions, risk reduction, and health promotion for diverse child populations.

How many awards were anticipated?

The funding opportunity anticipated approximately 7 awards.

What was the estimated total funding level?

The estimated total funding level was $12,000,000.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are generally not required to contribute non-federal funds as a condition of the award.

What is the CFDA number for this program?

The CFDA number listed is 93.113 (Environmental Health).

When was the opportunity posted?

The opportunity was posted in early April 2012.

What was the application closing date?

The closing date listed was July 17, 2012.

What does the archive date indicate?

The archive date is August 17, 2012. Along with the 2012 posting and closing dates, this indicates the announcement is historical rather than a currently open competition.

Who was eligible to apply?

Eligibility was broad across many domestic organization types, including public and private institutions of higher education, state and local governments, independent school districts, small businesses, for-profit organizations, public housing authorities/Indian housing authorities, and nonprofit organizations with or without 501(c)(3) status (with distinctions noted for institutions of higher education).

Are specific institution types explicitly mentioned as eligible?

Yes. The announcement explicitly lists categories such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and tribal organizations and governments (including federally recognized tribal governments).

Are non-U.S. (non-domestic) entities allowed to apply?

No. The opportunity states that non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply.

Are any foreign activities allowed under this program?

Yes, in a limited way. While non-U.S. entities cannot apply, the announcement notes that foreign components (as defined in the NIH Grants Policy Statement) are allowed, which typically refers to discrete parts of a project conducted outside the U.S. under NIH policy conditions.

Where could applicants find the full official announcement?

The FOA provided an NIH grants web link to the complete announcement text.

Who was listed for technical help with the announcement link or access?

The FOA listed the NIH Office of Extramural Research (OER) webmaster as the contact for technical issues accessing or linking to the announcement.

What core expectation separates a competitive center application from a collection of separate projects?

Based on the announcement language, a competitive application would demonstrate strong links between disciplines through shared aims, cross-cutting methods, and coordinated interpretation of results, rather than simply placing different experts or projects side-by-side.

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SBIR E learning for HAZMAT and Emergency Response (SBIR R43/R44) Apply for RFA ES 12 005

Funding Number: RFA ES 12 005
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Funding Number: PA 12 188
Agency: National Institutes of Health
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Transgenerational Inheritance in Mammals After Environmental Exposure (TIME) (R01) Apply for RFA ES 12 006

Funding Number: RFA ES 12 006
Agency: National Institutes of Health
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Transgenerational Inheritance in Mammals After Environmental Exposure (TIME) (R21) Apply for RFA ES 12 007

Funding Number: RFA ES 12 007
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $200,000
Environmental Influences on the Microbiome (R21) Apply for RFA ES 12 009

Funding Number: RFA ES 12 009
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $200,000
Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (SBIR R43) Apply for RFA ES 13 003

Funding Number: RFA ES 13 003
Agency: National Institutes of Health
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Funding Amount: $225,000
Environmental Health Sciences (EHS) Core Centers (P30) Apply for RFA ES 13 002

Funding Number: RFA ES 13 002
Agency: National Institutes of Health
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Funding Amount: $100,000
Land Use Change and Disease Emergence Apply for RFI 486 13 00002

Funding Number: RFI 486 13 00002
Agency: Thailand USAID Bangkok
Category: Environment Health
Funding Amount: Case Dependent
Mechanism for Time Sensitive Research Opportunities in Environmental Health Sciences (R21) Apply for PAR 13 136

Funding Number: PAR 13 136
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $200,000
Twin Cities Clean Cities Initiative in the Mississippi National River and Recreation Area (MISS) NOI Not a Request for Proposals Apply for P13AP00046

Funding Number: P13AP00046
Agency: National Park Service
Category: Environment Health
Funding Amount: $128,000
Notice of Intent Apply for F13AS00238

Funding Number: F13AS00238
Agency: Fish and Wildlife Service
Category: Environment Health
Funding Amount: $150,000
Research Linking Environmental Exposure to Alzheimers Disease (R01) Apply for RFA ES 13 006

Funding Number: RFA ES 13 006
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $350,000
Research Linking Environmental Exposure to Neurodegenerative Disease (R21) Apply for RFA ES 13 007

Funding Number: RFA ES 13 007
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $200,000
Novel Methods for Obtaining Molecular Information from Archived Tissue Samples (SBIR R43/R44) Apply for RFA ES 13 009

Funding Number: RFA ES 13 009
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: Case Dependent
The Role of Environmental Exposures in the Development of Autoimmune Disease (R21) Apply for RFA ES 13 011

Funding Number: RFA ES 13 011
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $200,000
Validation and Demonstration of Devices for Environmental Exposure Assessment (R21/R33) Apply for RFA ES 13 013

Funding Number: RFA ES 13 013
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: Case Dependent
Outstanding New Environmental Scientist (ONES) Award (R01) Apply for RFA ES 13 014

Funding Number: RFA ES 13 014
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $250,000
Environmental Health Sciences Core Centers (EHS CC) (P30) Apply for RFA ES 13 012

Funding Number: RFA ES 13 012
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $1,300,000
NIH Revision Awards for Creating Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER)(R01) Apply for PAR 14 050

Funding Number: PAR 14 050
Agency: National Institutes of Health
Category: Environment Health
Funding Amount: $250,000
Developing Mercury Inventories for Artisanal and Small scale Gold Mining Sectors in Southeast Asia Apply for OES OMM 14 001

Funding Number: OES OMM 14 001
Agency: Ocean and International Environmental Scientific
Category: Environment Health
Funding Amount: $200,000

 

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