Opportunity Information: Apply for PAR 10 235

  • The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Climate Change and Health Assessing and Modeling Population Vulnerability to Climate Change (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.879 Medical Library Assistance 93.989 International Research and Research Training.
  • This funding opportunity was created on Jul 21, 2010 and posted on Jul 21, 2010.
  • Applicants must submit their applications by May 24, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Public housing authorities/Indian housing authorities Special district governments Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Small businesses State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses Independent school districts.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Climate Change and Health: Assessing and Modeling Population Vulnerability to Climate Change (R21) opportunity (Funding Opportunity Number PAR-10-235) is a National Institutes of Health (NIH) exploratory grant program led by the National Institute of Environmental Health Sciences (NIEHS), with participation from multiple NIH components including FIC, NCI, NCMHD, NHLBI, NIA, NIBIB, NICHD, NLM, and OBSSR. The central focus is on understanding why some groups of people are more vulnerable than others to climate change related health threats, and on generating practical knowledge that can guide real-world adaptation and public health action. In plain terms, the program is looking for research that can explain and predict which populations are at higher risk as climate driven exposures and hazards intensify, and what factors drive that increased risk.

The FOA encourages applications that study differential risk factors and population characteristics linked to heightened vulnerability to climate sensitive exposures, diseases, and other adverse health outcomes. That can include applied research projects that test specific hypotheses (for example, evaluating how age, chronic disease burden, housing quality, occupational exposure, neighborhood heat islands, access to health care, or socioeconomic constraints shape health outcomes during heat waves, wildfires, flooding, or shifting infectious disease patterns). It can also include more methods-oriented projects that build general models, tools, or approaches for identifying and characterizing vulnerability across places and populations, such as statistical or computational models that integrate climate variables with demographic, geographic, clinical, and social data to map risk and forecast impacts.

A key theme running through the announcement is that the desired end product is not just academic insight, but actionable evidence that helps inform climate change adaptation strategies and public health interventions. The goal is to reduce both current and future vulnerability by improving how decision-makers identify at-risk groups, anticipate health burdens, and target prevention, preparedness, and response efforts. Because vulnerability is shaped by intersecting environmental, biological, social, and infrastructural factors, the FOA explicitly anticipates multidisciplinary teams. Competitive projects are expected to draw from health sciences and climatology, and often also from geography, modeling, statistics, demography, and social and behavioral sciences. The announcement also encourages partnerships beyond academia, including collaboration with community-based or advocacy organizations, public health officials, urban planners, and other practitioners who can help ensure that research outputs are relevant and usable.

The mechanism of support is the NIH Exploratory/Developmental Research Grant (R21), which is typically used for early-stage, proof-of-concept, or innovative studies that can open up new directions or establish feasibility for larger research efforts. The award ceiling listed is $200,000, and the program notes that award size and duration may vary depending on the proposed work. It also notes that the total funds awarded and the number of awards will depend on the number of applications received, their quality, their duration, and their requested budgets. There is no cost sharing or matching requirement.

Eligibility is broad and includes many types of organizations that can carry out research, such as public and private institutions of higher education, state and local governments, county and city or township governments, special district governments, independent school districts, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), small businesses, and other for-profit organizations (excluding small businesses where specified). It also includes Native American tribal governments (federally recognized) and other tribal organizations, public housing authorities and Indian housing authorities, and a wide range of mission-focused institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations) and regional organizations, reflecting an intent to support research that may be local, regional, national, or international in scope.

This opportunity was posted and created on July 21, 2010, with an original and final closing date of May 24, 2012, and it was archived on June 24, 2012. It is associated with multiple CFDA numbers spanning environmental health, technology innovation for health, minority health and health disparities, cancer control, cardiovascular and lung diseases, child health and development, aging research, medical library assistance, and international research and research training, which signals the cross-cutting nature of climate change impacts across health domains and populations.

Overall, the FOA is best understood as an NIH effort to seed innovative, interdisciplinary research that clarifies who is most at risk from climate change related health impacts, why that risk is higher, and how to measure and model vulnerability in ways that directly support targeted adaptation planning and effective public health interventions.

Frequently Asked Questions (FAQs)

What is the title of this funding opportunity?

The opportunity is titled Climate Change and Health: Assessing and Modeling Population Vulnerability to Climate Change (R21).

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PAR-10-235.

Which federal agency runs this opportunity?

This is a National Institutes of Health (NIH) funding opportunity.

Which NIH institute leads the program?

The program is led by the National Institute of Environmental Health Sciences (NIEHS).

Which other NIH components participate?

Participating NIH components include: FIC, NCI, NCMHD, NHLBI, NIA, NIBIB, NICHD, NLM, and OBSSR.

What is the main purpose of this grant program?

The central purpose is to improve understanding of why some groups are more vulnerable than others to climate change related health threats, and to generate practical, actionable knowledge that can inform real-world climate adaptation strategies and public health interventions.

What kinds of research questions is the FOA trying to answer?

The FOA seeks research that can explain and predict which populations are at higher risk as climate driven exposures and hazards intensify, and identify the factors that drive increased risk across different places and groups.

What does "population vulnerability" mean in the context of this opportunity?

Based on the FOA description, vulnerability is shaped by intersecting environmental, biological, social, and infrastructural factors that influence how climate sensitive hazards translate into adverse health outcomes for different populations.

What types of climate-related hazards and exposures are referenced?

Examples mentioned include heat waves, wildfires, flooding, and shifting infectious disease patterns, along with other climate sensitive exposures linked to disease and adverse health outcomes.

What kinds of risk factors or population characteristics can projects examine?

The FOA highlights differential risk factors and characteristics such as age, chronic disease burden, housing quality, occupational exposure, neighborhood heat islands, access to health care, and socioeconomic constraints, among others.

Are both applied studies and methods/modeling studies encouraged?

Yes. The FOA encourages (1) applied research that tests specific hypotheses about drivers of vulnerability and health outcomes, and (2) methods-oriented projects that develop general models, tools, or approaches to identify and characterize vulnerability across populations and places.

What types of models or tools does the FOA describe?

The FOA mentions building statistical or computational models that integrate climate variables with demographic, geographic, clinical, and social data to map risk and forecast impacts.

Does the FOA prioritize actionable outcomes?

Yes. A recurring theme is that the end product should go beyond academic insight and provide actionable evidence that can help decision-makers identify at-risk groups, anticipate health burdens, and target prevention, preparedness, and response efforts.

How is this funding mechanism described (what is an R21 in this context)?

This opportunity uses the NIH Exploratory/Developmental Research Grant (R21) mechanism, described as supporting early-stage, proof-of-concept, or innovative studies that can establish feasibility and open new directions for larger research efforts.

What is the award budget ceiling?

The listed award ceiling is $200,000.

Can award size and project duration vary?

Yes. The FOA notes that award size and duration may vary depending on the proposed work.

How are the total number of awards and total funds determined?

The FOA states that total funds awarded and the number of awards depend on the number of applications received, their quality, their duration, and their requested budgets.

Is cost sharing or matching required?

No. The FOA indicates there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad and includes many organization types, including public and private higher education institutions, state and local governments, county/city/township governments, special district governments, independent school districts, nonprofits (both 501(c)(3) and non-501(c)(3)), small businesses, and other for-profit organizations (excluding small businesses where specified).

Are tribal entities eligible?

Yes. Eligible applicants include Native American tribal governments (federally recognized) and other tribal organizations.

Are housing authorities eligible?

Yes. The eligibility list includes public housing authorities and Indian housing authorities.

Are mission-focused institutions (such as HBCUs and Hispanic-serving institutions) eligible?

Yes. The FOA explicitly includes a wide range of mission-focused institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Can organizations outside the United States apply?

Yes. The eligibility list includes non-U.S. entities (foreign organizations) and regional organizations, reflecting support for research that may be local, regional, national, or international in scope.

Are multidisciplinary teams expected or encouraged?

Yes. The FOA anticipates multidisciplinary teams, with competitive projects expected to draw from health sciences and climatology, and often also from geography, modeling, statistics, demography, and social and behavioral sciences.

Are collaborations beyond academia encouraged?

Yes. The FOA encourages partnerships with organizations and practitioners such as community-based or advocacy organizations, public health officials, urban planners, and others who can help ensure research outputs are relevant and usable.

What is the timeline for this opportunity (posting and closing dates)?

The opportunity was posted/created on July 21, 2010. The original and final closing date was May 24, 2012.

Is this FOA still active?

No. The opportunity was archived on June 24, 2012.

What do the CFDA associations suggest about the scope of the research?

The FOA is associated with multiple CFDA numbers across areas including environmental health, technology innovation for health, minority health and health disparities, cancer control, cardiovascular and lung diseases, child health and development, aging research, medical library assistance, and international research and research training, signaling that climate change impacts are considered cross-cutting across health domains and populations.

In one sentence, what is NIH trying to seed with this program?

The FOA is intended to seed innovative, interdisciplinary research that clarifies who is most at risk from climate change related health impacts, why risk is higher for some groups, and how to measure and model vulnerability in ways that directly support targeted adaptation planning and effective public health interventions.

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