Clinical Research on Mental Illnesses in Older Adults (R01) | Apply Online

Opportunity Summary:

The funding opportunity titled Clinical Research on Mental Illnesses in Older Adults (R01) (Funding Opportunity Number PA 07-163) is a National Institute of Mental Health (NIMH), National Institutes of Health (NIH) announcement aimed at supporting clinical research that meaningfully reduces the burden of mental illnesses among older adults. The central focus is on improving the evidence base for preventing, identifying, understanding, and treating mental health conditions in later life, with the broader goal of improving outcomes and quality of life for older individuals and the systems that serve them. NIMH emphasizes that it has a long-standing commitment to research in this population, and this announcement is meant to strengthen and expand that commitment through new and more intensive investigator-initiated work.

A major theme of the announcement is building momentum in late-life mental health research by encouraging more investigators to engage in this area and by promoting interdisciplinary approaches. In practice, that means the FOA is intended not only for established geriatric mental health researchers, but also for investigators from adjacent fields who can bring fresh methods, perspectives, and collaborations. The interdisciplinary emphasis suggests projects may benefit from teams that bridge clinical psychiatry or psychology with geriatrics, neurology, primary care, epidemiology, health services research, implementation science, biostatistics, and other relevant disciplines, as long as the work remains clinical in nature and aligned with reducing illness burden in older populations.

The mechanism of support is the NIH Research Project Grant (R01), which is the standard NIH award mechanism for mature, hypothesis-driven research projects. The FOA also points out that applications with the same overall scientific scope could be considered under other NIH/NIMH mechanisms depending on project stage and scale, including the R03 (Small Research Grant), R21 (Exploratory/Developmental Grant), and the NIMH R34 (Clinical Exploratory Research Grant). This is an important signal that NIMH is trying to support a pipeline of studies ranging from smaller or early-stage investigations (like feasibility or pilot clinical studies) through to full-scale clinical research projects typical of an R01.

In terms of funding levels and the number of awards, the announcement does not set a fixed total dollar amount or a guaranteed number of funded projects. Instead, it explains that award size and duration will vary depending on the specific research proposed, and that the total amount awarded and number of awards will depend on factors such as the mix of mechanisms used, scientific quality, project length, and budget needs across the application pool. This is typical of NIH program announcements where the institute wants flexibility to fund the strongest applications across a range of clinical topics and approaches.

Eligibility is broad and includes many types of applicants. Eligible organizations include public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations (other than small businesses, which are listed separately), small businesses, and a wide variety of government entities such as state governments, county governments, city or township governments, special district governments, and independent school districts. The FOA explicitly allows applications from federally recognized tribal governments and other Native American tribal organizations, as well as public housing authorities/Indian housing authorities. It also states that foreign institutions are eligible to apply, eligible federal agencies may apply, and that faith-based and community-based organizations may apply as well. There is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of receiving an award.

From an administrative standpoint, this opportunity is categorized as a discretionary grant in the health area and is associated with CFDA 93.242 (Mental Health Research Grants). It was posted on December 13, 2006, and uses multiple receipt dates rather than a single one-time deadline, meaning applications could be accepted on a recurring schedule as described in the full announcement. The original and current closing date fields both indicate multiple receipt dates and direct applicants to the full FOA for specifics. The archive date listed is April 5, 2009, indicating that this particular announcement was ultimately archived, although similar topics may later reappear under newer NIMH funding announcements.

For applicants seeking the official details, the full announcement is linked through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-07-163.html. The contact provided for access or technical issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is intended for problems opening or linking to the opportunity rather than scientific or programmatic questions.

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