Opportunity Information: Apply for PA 14 179

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Clinical Trial Planning Grant for Interventions and Services to Improve Treatment and Prevention of HIV/AIDS (R34)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research.
  • This funding opportunity was created on Apr 17, 2014 and posted on Apr 17, 2014.
  • Applicants must submit their applications by Jan 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $225,000.00 in funding.
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Small businesses For profit organizations other than small businesses Public housing authorities/Indian housing authorities County governments Special district governments Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Clinical Trial Planning Grant for Interventions and Services to Improve Treatment and Prevention of HIV/AIDS (R34), Funding Opportunity Number PA 14-179, is a National Institutes of Health (NIH) discretionary grant program designed to help applicants do the up-front work needed to launch a well-designed, larger-scale HIV clinical trial or services study. The central purpose is to fund the planning, study design activities, and preliminary data collection that strengthen the scientific and operational foundation for later, more definitive research. The opportunity is explicitly oriented toward practical, real-world impact in HIV by supporting projects that either reduce HIV acquisition and transmission, improve treatment and care outcomes for people living with HIV, or combine both prevention and treatment goals in a single coherent research plan.

The FOA supports three main types of activities. First, it can fund the development and/or pilot testing of new interventions, which may include behavioral, social, structural, or service-delivery approaches intended to improve prevention or care outcomes. Second, it can fund the adaptation and/or pilot testing of interventions that already have demonstrated efficacy, with the goal of preparing them for broader effectiveness trials in different populations, settings, or delivery systems. Third, it can support innovative services research that needs preliminary testing, meaning research focused on how HIV prevention and care services are organized, delivered, accessed, integrated, or optimized in real service settings, where early feasibility and implementation evidence is necessary before scaling.

Projects funded under this mechanism are time-limited and budget-limited, emphasizing planning and proof-of-concept rather than full-scale trials. Awards are limited to a maximum project period of three years, and the listed award ceiling is $225,000. The announcement also states there is no cost sharing or matching requirement, which generally lowers barriers for applicants by not requiring institutional or partner funds to be committed as a condition of award.

Eligibility is broad and includes a wide range of domestic and non-domestic organizations and governmental entities. Eligible applicants include nonprofit organizations (both 501(c)(3) and non-501(c)(3), excluding higher education institutions where specified), public and private institutions of higher education, state and local government entities (including state governments, county governments, city or township governments, special district governments, and independent school districts), public housing authorities/Indian housing authorities, tribal governments (both federally recognized and other than federally recognized) and other Native American tribal organizations, as well as for-profit organizations (including small businesses and other for-profit entities). The FOA also identifies additional eligible groups such as faith-based and community-based organizations, U.S. territories or possessions, regional organizations, certain minority-serving institutions (including HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities), eligible federal agencies, and foreign (non-U.S.) organizations.

From an administrative standpoint, this opportunity was posted and created on April 17, 2014, with an original and current closing date of January 7, 2017, and it was archived on February 7, 2017. It is categorized under health-related funding activities and is associated with CFDA numbers 93.242 (Mental Health Research Grants), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research), reflecting the cross-cutting nature of HIV research spanning behavioral health, infectious disease, and microbiology-related domains.

The complete announcement and official instructions were provided through NIH, with an additional information link pointing to the NIH Grants Guide page for PA 14-179. For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster via FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is the Clinical Trial Planning Grant for Interventions and Services to Improve Treatment and Prevention of HIV/AIDS (R34)?

This opportunity (Funding Opportunity Number PA 14-179) is a National Institutes of Health (NIH) discretionary grant program that supports the up-front planning work needed to launch a well-designed, larger-scale HIV clinical trial or HIV services study. It is intended to fund planning, study design activities, and preliminary data collection that strengthen the scientific and operational foundation for later, more definitive research.

What is the main purpose of this R34 funding opportunity?

The central purpose is to support planning and proof-of-concept activities that help applicants prepare for a future, larger clinical trial or services study. The emphasis is on building a strong scientific and operational base (for example, refining study design and collecting preliminary data) rather than running a full-scale trial.

What HIV-related goals does the FOA prioritize?

The FOA is oriented toward practical, real-world impact in HIV by supporting projects that (1) reduce HIV acquisition and transmission, (2) improve treatment and care outcomes for people living with HIV, or (3) combine prevention and treatment goals in a single coherent research plan.

What types of activities can be funded under this FOA?

The FOA supports three main types of activities: (1) development and/or pilot testing of new interventions, (2) adaptation and/or pilot testing of interventions with demonstrated efficacy to prepare for broader effectiveness trials, and (3) innovative services research that needs preliminary testing in real service settings.

What kinds of interventions are mentioned as eligible for development or pilot testing?

The FOA notes that interventions may include behavioral, social, structural, or service-delivery approaches intended to improve HIV prevention or care outcomes.

Does the FOA support adapting interventions that already work?

Yes. The FOA can fund the adaptation and/or pilot testing of interventions that already have demonstrated efficacy, with the goal of preparing them for broader effectiveness trials in different populations, settings, or delivery systems.

What is meant by "innovative services research that needs preliminary testing"?

This refers to research focused on how HIV prevention and care services are organized, delivered, accessed, integrated, or optimized in real service settings, where early feasibility and implementation evidence is needed before scaling.

Is this funding meant for full-scale clinical trials?

No. Projects funded under this mechanism are time-limited and budget-limited, emphasizing planning and proof-of-concept rather than full-scale trials.

What is the maximum project period for an award?

Awards are limited to a maximum project period of three years.

What is the listed award ceiling for this opportunity?

The listed award ceiling is $225,000.

Is cost sharing or matching required?

No. The announcement states there is no cost sharing or matching requirement.

Who is eligible to apply for this FOA?

Eligibility is broad and includes domestic and non-domestic organizations and governmental entities, including nonprofits, public and private institutions of higher education, state and local governments, tribal governments and other Native American tribal organizations, public housing authorities/Indian housing authorities, for-profit organizations (including small businesses), eligible federal agencies, and foreign (non-U.S.) organizations.

Are nonprofit organizations eligible?

Yes. Eligible applicants include nonprofit organizations, including both 501(c)(3) and non-501(c)(3) organizations (with exclusions noted in the provided description where specified).

Are colleges and universities eligible to apply?

Yes. Public and private institutions of higher education are included among eligible applicants in the information provided.

Are state and local government agencies eligible?

Yes. The FOA includes state governments, county governments, city or township governments, special district governments, and independent school districts as eligible applicants.

Are tribal governments and Native American tribal organizations eligible?

Yes. The FOA includes tribal governments (both federally recognized and other than federally recognized) as well as other Native American tribal organizations.

Are public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.

Are for-profit organizations eligible, including small businesses?

Yes. For-profit organizations are eligible, including small businesses and other for-profit entities.

Are faith-based and community-based organizations eligible?

Yes. The FOA identifies faith-based and community-based organizations among eligible groups.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are listed among eligible groups.

Are minority-serving institutions specifically included in eligibility?

Yes. The FOA identifies certain minority-serving institutions, including HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities.

Are foreign (non-U.S.) organizations eligible to apply?

Yes. The FOA includes foreign (non-U.S.) organizations as eligible applicants.

When was this funding opportunity posted and created?

It was posted and created on April 17, 2014.

What were the closing dates for this opportunity?

The information provided lists an original closing date and a current closing date of January 7, 2017.

Has this opportunity been archived?

Yes. It was archived on February 7, 2017.

What funding activity category is this opportunity associated with?

It is categorized under health-related funding activities.

Which CFDA numbers are associated with this FOA?

The FOA is associated with CFDA numbers 93.242 (Mental Health Research Grants), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research).

Where can applicants find the complete announcement and official instructions?

The complete announcement and official instructions were provided through NIH, with an additional information link pointing to the NIH Grants Guide page for PA 14-179.

Who should be contacted for access or technical issues related to the announcement?

The contact listed for access or technical issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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