Opportunity Information: Apply for PAS 10 273
Apply for PAS 10 273
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Clinically Relevant Comparative Effectiveness of Alcoholism Treatments (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on Aug 25, 2010 and posted on Aug 25, 2010.
- Applicants must submit their applications by Sep 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
- Eligible applicants include: Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) State governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The Clinically Relevant Comparative Effectiveness of Alcoholism Treatments (R01) opportunity (Funding Opportunity Number PAS 10-273) is a National Institute on Alcohol Abuse and Alcoholism (NIAAA), NIH funding announcement aimed at strengthening real-world evidence on how well different alcohol use disorder (AUD) treatments work in typical clinical practice. The central emphasis is on comparative effectiveness research, meaning studies that directly compare pharmacologic treatments, behavioral interventions, or combinations of the two as they are delivered in everyday care settings rather than highly controlled, idealized research environments. The intent is to generate practical findings that clinicians, health systems, and patients can use to make better-informed treatment decisions, ultimately improving outcomes and reducing harms associated with AUD interventions.
A key feature of the announcement is its focus on variation in treatment response and delivery. Applicants are encouraged to study how patient characteristics influence which treatments are most effective, recognizing that AUD is not a one-size-fits-all condition and that factors such as clinical profile, comorbidities, severity, and other individual differences can affect outcomes. At the same time, the FOA explicitly invites research on the organizational, financial, and management conditions that either support or obstruct the delivery of evidence-based AUD services. In other words, it is not only about whether an intervention works, but also about whether it can be implemented reliably in real clinics, what barriers prevent uptake, and what system-level features help programs deliver effective care.
The mechanism of support is the NIH R01, which typically funds substantial, multi-year research projects led by an experienced investigator team. The funding is discretionary and falls under the health category, with CFDA number 93.273 (Alcohol Research Programs). For fiscal year 2011, NIAAA indicated an estimated total funding level of $1.5 million in total costs set aside for this initiative, with an expectation of making up to six awards. The actual number of awards and total dollars distributed are contingent on the volume and quality of applications received, as well as project duration and proposed budgets.
Eligibility is broad and includes many types of institutions and organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, state governments, federally recognized Native American tribal governments, and tribal organizations. The FOA also allows participation from nonprofits with and without 501(c)(3) status, for-profit organizations (including small businesses and other for-profits), and additional categories such as faith-based or community-based organizations, U.S. territories or possessions, and eligible federal agencies. It specifically notes eligibility for groups and institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions. Non-U.S. entities (foreign organizations) and regional organizations are also listed among eligible applicants, reflecting an openness to diverse research settings and collaborative structures. The opportunity does not require cost sharing or matching funds.
In practical terms, this FOA is designed for research teams that can evaluate AUD treatments as they are actually delivered in routine care, compare credible alternatives head-to-head, and produce results that are directly useful for clinical decision-making and service delivery. It also signals strong interest in implementation-relevant evidence, including how financing, staffing models, leadership practices, workflow, and organizational culture influence whether evidence-based AUD treatments are adopted and sustained. The original posting date was August 25, 2010, with a closing date of September 7, 2013 (archived October 8, 2013), indicating it was a time-limited opportunity during that period. For full details, the announcement referenced the NIH grants guide page for PAS 10-273.
Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The opportunity is titled Clinically Relevant Comparative Effectiveness of Alcoholism Treatments (R01).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PAS 10-273.
Which agency is offering this opportunity?
This is a funding announcement from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).
What is the main purpose of this FOA?
The main purpose is to strengthen real-world evidence on how well different alcohol use disorder (AUD) treatments work in typical clinical practice, with findings intended to be useful for clinicians, health systems, and patients.
What type of research is emphasized?
The FOA emphasizes comparative effectiveness research, meaning studies that directly compare credible treatment alternatives as they are delivered in everyday care settings rather than in highly controlled research environments.
What kinds of treatments can be compared under this opportunity?
The announcement highlights comparisons among pharmacologic treatments, behavioral interventions, and combinations of pharmacologic and behavioral approaches as delivered in routine care.
Does the FOA focus on real-world clinical settings or controlled research settings?
The central emphasis is on everyday care settings and typical clinical practice, not idealized or tightly controlled research conditions.
Why is variation in treatment response important in this FOA?
The FOA encourages research on how patient characteristics influence which treatments are most effective, recognizing that AUD treatment is not one-size-fits-all and that differences such as clinical profile, comorbidities, and severity can affect outcomes.
What patient factors does the FOA suggest may influence outcomes?
Based on the announcement, examples include clinical profile, comorbidities, severity, and other individual differences that may affect treatment response.
Does this opportunity include implementation-related research?
Yes. The FOA explicitly invites research on organizational, financial, and management conditions that support or obstruct delivery of evidence-based AUD services in real clinics.
What kinds of system-level or organizational topics are relevant?
The FOA signals interest in factors such as financing, staffing models, leadership practices, workflow, and organizational culture that influence whether evidence-based AUD treatments are adopted and sustained.
What is the mechanism of support for this funding opportunity?
The mechanism of support is an NIH R01.
What does it mean that the mechanism is an R01?
As described in the announcement, an R01 typically supports substantial, multi-year research projects led by an experienced investigator team.
What is the CFDA number associated with this program?
The CFDA number is 93.273 (Alcohol Research Programs).
How much total funding was NIAAA expecting to make available?
For fiscal year 2011, NIAAA indicated an estimated total of $1.5 million in total costs set aside for this initiative.
How many awards were expected?
NIAAA expected to make up to six awards, depending on the volume and quality of applications, as well as project durations and proposed budgets.
Is the number of awards guaranteed?
No. The announcement states that the actual number of awards and total dollars distributed are contingent on factors such as application volume, application quality, project duration, and proposed budgets.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching funds.
Who is eligible to apply?
Eligibility is broad and includes many organization types, such as institutions of higher education, governments, nonprofits, for-profits, tribal entities, U.S. territories/possessions, eligible federal agencies, and non-U.S. (foreign) entities and regional organizations.
Are public and state-controlled institutions of higher education eligible?
Yes, public and state-controlled institutions of higher education are listed as eligible applicants.
Are private institutions of higher education eligible?
Yes, private institutions of higher education are listed as eligible applicants.
Are state governments eligible to apply?
Yes, state governments are listed as eligible applicants.
Are federally recognized tribal governments eligible?
Yes, federally recognized Native American tribal governments are listed as eligible.
Are tribal organizations eligible?
Yes, tribal organizations are included among eligible applicants.
Are nonprofits eligible, including those without 501(c)(3) status?
Yes. The FOA allows participation from nonprofits with and without 501(c)(3) status.
Are for-profit organizations eligible?
Yes. The FOA includes for-profit organizations, including small businesses and other for-profit entities.
Are faith-based or community-based organizations eligible?
Yes, the announcement includes faith-based and community-based organizations among eligible applicant categories.
Are U.S. territories or possessions eligible to apply?
Yes, U.S. territories or possessions are listed as eligible applicants.
Are eligible federal agencies allowed to apply?
Yes, eligible federal agencies are included in the eligibility list.
Are non-U.S. (foreign) organizations eligible?
Yes, non-U.S. entities (foreign organizations) are listed among eligible applicants.
Are regional organizations eligible?
Yes, regional organizations are listed among eligible applicants.
Does the FOA specifically encourage applications from certain institution types?
The announcement specifically notes eligibility for institution types including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.
What is the category of this funding opportunity?
The announcement describes the funding as discretionary and under the health category.
What kinds of outcomes or impact is this FOA trying to achieve?
The intent is to produce practical, clinically relevant findings that help clinicians, health systems, and patients make better-informed treatment decisions, with the broader goal of improving outcomes and reducing harms associated with AUD interventions.
When was this opportunity posted and when did it close?
The original posting date was August 25, 2010. The closing date was September 7, 2013, and it was archived on October 8, 2013.
Where were applicants directed for full details?
The announcement references the NIH grants guide page for PAS 10-273 for full details.
Browse more opportunities from the same category: Health
Next opportunity: Cooperative Ecosystem Studies Unit, Californian CESU
Previous opportunity: Colorado State University Migration of Images and Database of National Park Service Water Right Dockets
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PAS 10 273
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (PAS 10 273) also looked into and applied for these:
| Funding Opportunity |
|---|
| Service Area Competitions Apply for HRSA 11 007 Funding Number: HRSA 11 007 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competitions Apply for HRSA 11 008 Funding Number: HRSA 11 008 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competitions Apply for HRSA 11 009 Funding Number: HRSA 11 009 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competitions Apply for HRSA 11 010 Funding Number: HRSA 11 010 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Ryan White Part B HIV Care Grant Program Apply for HRSA 11 061 Funding Number: HRSA 11 061 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competitions Apply for HRSA 11 011 Funding Number: HRSA 11 011 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competitions Apply for HRSA 11 012 Funding Number: HRSA 11 012 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competitions Apply for HRSA 11 013 Funding Number: HRSA 11 013 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Service Area Competitions Apply for HRSA 11 014 Funding Number: HRSA 11 014 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Improving Evidence Based Mental Health Screening and Treatment for Persons with Mental Disorders in the Justice System (R34) Apply for RFA MH 11 061 Funding Number: RFA MH 11 061 Agency: National Institutes of Health Category: Health Funding Amount: $450,000 |
| Improving Evidence Based Mental Health Screening and Treatment for Persons with Mental Disorders in the Justice System (R01) Apply for RFA MH 11 060 Funding Number: RFA MH 11 060 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| Orphans and Vulnerable Children (OVC) Program Apply for USAID ETHIOPIA 663 10 000001 RFA Funding Number: USAID ETHIOPIA 663 10 000001 RFA Agency: Ethiopia USAID Addis Ababa Category: Health Funding Amount: $92,106,320 |
| NIDCR Small Grant Program for New Investigators (R03) Apply for PAR 10 275 Funding Number: PAR 10 275 Agency: National Institutes of Health Category: Health Funding Amount: $150,000 |
| Rural Health Network Development Program Apply for HRSA 11 089 Funding Number: HRSA 11 089 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Biomarkers of Alcohol Consumption and Alcohol induced Tissue Injury (STTR R41/R42) Apply for RFA AA 11 005 Funding Number: RFA AA 11 005 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Biomarkers of Alcohol Consumption and Alcohol induced Tissue Injury (SBIR R43/R44) Apply for RFA AA 11 004 Funding Number: RFA AA 11 004 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| MCH Research Apply for HRSA 11 016 Funding Number: HRSA 11 016 Agency: Health Resources and Services Administration Category: Health Funding Amount: $300,000 |
| Modeling the Scientific Workforce (U01) Apply for RFA GM 11 007 Funding Number: RFA GM 11 007 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Revolutionary Genome Sequencing Technologies The 1000 Genome (R01) Apply for RFA HG 10 012 Funding Number: RFA HG 10 012 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Revolutionary Genome Sequencing Technologies The 1000 Genome (R21) Apply for RFA HG 10 013 Funding Number: RFA HG 10 013 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PAS 10 273", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.