Opportunity Information: Apply for PAR 12 001

  • The National Institutes of Health in the education environment food and nutrition health sector is offering a public funding opportunity titled "Collaborations with National Centers for Biomedical Computing (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.172 Human Genome Research 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.397 Cancer Centers Support Grants 93.398 Cancer Research Manpower 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.859 Biomedical Research and Research Training.
  • This funding opportunity was created on Oct 11, 2011 and posted on Oct 7, 2011.
  • Applicants must submit their applications by Jan 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) State governments Independent school districts Native American tribal governments (Federally recognized) Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Small businesses Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

Collaborations with National Centers for Biomedical Computing (R01) (Funding Opportunity Number PAR-12-001) is an NIH grant opportunity designed to support research projects led by individual investigators or small teams that actively collaborate with the NIH Common Fund National Centers for Biomedical Computing (NCBCs). The core idea is to broaden participation in a national biomedical computing ecosystem by encouraging outside researchers to build on, extend, test, and apply the computational tools, platforms, and scientific use-cases (often called "application drivers") being developed by the NCBCs. Rather than funding completely standalone efforts, the FOA is aimed at projects that plug into the NCBC network and use those centers as starting points for new computational methods, new integrations, or new biomedical and behavioral research applications.

The program uses the R01 research project grant mechanism, meaning it is structured to fund substantial, hypothesis-driven or problem-driven research collaborations that can produce clear scientific and technical outcomes. In practice, a competitive application would be expected to show a real working relationship with one or more NCBCs and to explain how the proposed work will leverage NCBC resources while also contributing back to the broader community. The intended impact is not just a single research result, but progress toward an "excellent biomedical computing environment" across the country, where tools are more interoperable, more widely usable, and better grounded in real biological and behavioral research needs.

This opportunity was offered by the National Institutes of Health as a discretionary grant program, and it spans a wide range of health and biomedical domains as reflected in its many CFDA program associations. Those include environmental health, human genome research, sleep disorders, mental health, alcohol research, technology innovations for human health, multiple cancer research areas, cardiovascular and lung diseases, blood and kidney-related research, diabetes and digestive diseases, and broader biomedical research and research training. That breadth signals that NIH expected NCBC-based computing approaches to be relevant across many disease areas and research communities, not limited to one specialty.

Eligibility was broad and inclusive. Applicants could come from public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (other than small businesses, though small businesses were also listed as eligible), and many types of government entities (state, county, city/township, special district, independent school districts, and certain public housing authorities). The announcement also explicitly included a wide set of mission-driven and capacity-building institutions and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations, among others. Importantly, non-U.S. (foreign) institutions were eligible to apply, non-U.S. components of U.S. organizations were eligible, and foreign components were allowed under NIH policy, indicating an openness to international expertise when it strengthens the collaborative computing and biomedical goals.

From an administrative standpoint, the FOA did not require cost sharing or matching funds. It was posted on October 7, 2011 (created October 11, 2011). The original closing date was September 7, 2014, with a later listed current closing date of January 7, 2015, and it was archived on January 8, 2015. The administering agency was NIH, and the primary public reference for the participating NCBCs was provided via the NCBC website (ncbcs.org), with the full FOA details available through the NIH grants guide page linked in the announcement.

Overall, PAR-12-001 can be understood as an NIH effort to turn the NCBC program into a wider, more connected national resource by funding external collaborators who could help validate, disseminate, improve, and creatively apply NCBC-developed computational capabilities to concrete biomedical and behavioral research problems.

Frequently Asked Questions (FAQs)

What is the PAR-12-001 funding opportunity?

PAR-12-001, titled "Collaborations with National Centers for Biomedical Computing (R01)," is an NIH grant opportunity intended to support research projects that actively collaborate with one or more NIH Common Fund National Centers for Biomedical Computing (NCBCs). The emphasis is on extending, testing, integrating, or applying NCBC-developed computational tools, platforms, and scientific use-cases in ways that strengthen the broader biomedical computing ecosystem.

What does "Collaborations with National Centers for Biomedical Computing" mean in practice?

In practice, it means the proposed R01 project is not designed as a standalone effort. Instead, the project is expected to "plug into" the NCBC network by using NCBC resources as a starting point and showing an active collaboration with one or more NCBCs. The work may build on, extend, test, or apply NCBC tools, platforms, or application drivers, and it should also contribute back to the larger community by improving interoperability, usability, or scientific relevance.

What is the main goal of this NIH program?

The main goal is to broaden participation in a national biomedical computing ecosystem by encouraging outside researchers to leverage and advance NCBC-developed computational capabilities. NIH framed the intended outcome as progress toward an "excellent biomedical computing environment" where tools are more interoperable, more widely usable, and better grounded in real biological and behavioral research needs.

What grant mechanism does this opportunity use?

This opportunity uses the NIH R01 research project grant mechanism. The R01 structure is intended for substantial, hypothesis-driven or problem-driven research collaborations that can deliver clear scientific and technical outcomes.

What types of projects were encouraged under PAR-12-001?

Projects were encouraged when they build on, extend, test, integrate, or apply computational tools, platforms, and scientific use-cases (application drivers) being developed by the NCBCs. The opportunity was designed to support new computational methods, new integrations, and new biomedical and behavioral research applications that leverage NCBC resources and strengthen the shared computing environment.

Are completely independent or standalone projects a good fit for this FOA?

Based on the description provided, the FOA is aimed at projects that connect to and leverage the NCBC network rather than funding completely standalone efforts. A strong application would be expected to demonstrate a real working relationship with one or more NCBCs and explain how NCBC resources will be used as a foundation for the proposed work.

What are "application drivers" in the context of NCBCs?

"Application drivers" is the term used for the scientific use-cases being developed by the NCBCs. These are concrete biomedical or behavioral research problems and workflows that drive tool development and help ensure computational platforms are grounded in real research needs.

Who is the administering agency for this funding opportunity?

The administering agency is the National Institutes of Health (NIH).

Is this a discretionary grant program?

Yes. The opportunity is described as an NIH discretionary grant program.

What research areas or domains does this opportunity relate to?

The opportunity spans a wide range of health and biomedical domains, as reflected by its many CFDA program associations. The listed areas include environmental health, human genome research, sleep disorders, mental health, alcohol research, technology innovations for human health, multiple cancer research areas, cardiovascular and lung diseases, blood and kidney-related research, diabetes and digestive diseases, and broader biomedical research and research training. This breadth signals that NCBC-based computing approaches were expected to be relevant across many disease areas and research communities.

What kinds of organizations were eligible to apply?

Eligibility was broad. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (other than small businesses, though small businesses were also listed as eligible), and many types of government entities such as state, county, city/township, special district, independent school districts, and certain public housing authorities.

Were minority-serving or capacity-building institutions explicitly included?

Yes. The announcement explicitly included institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations, among others.

Could non-U.S. (foreign) institutions apply?

Yes. The opportunity explicitly states that non-U.S. (foreign) institutions were eligible to apply. In addition, non-U.S. components of U.S. organizations were eligible, and foreign components were allowed under NIH policy.

Does this FOA require cost sharing or matching funds?

No. The FOA did not require cost sharing or matching funds.

When was PAR-12-001 posted and when did it close?

The FOA was posted on October 7, 2011 (created October 11, 2011). The original closing date was September 7, 2014, and a later listed current closing date was January 7, 2015. It was archived on January 8, 2015.

Where could applicants find information about the participating NCBCs?

The primary public reference for the participating NCBCs was provided via the NCBC website (ncbcs.org). Full FOA details were available through the NIH grants guide page linked in the announcement.

What makes an application competitive under this opportunity, based on the description?

A competitive application would be expected to show an active, real working relationship with one or more NCBCs, clearly explain how the project will leverage NCBC resources, and describe how the work will contribute back to the broader community (for example, by improving interoperability, usability, validation, dissemination, integration, or real-world biomedical and behavioral application of NCBC capabilities).

What is the overall intended impact of funding these collaborations?

The intended impact goes beyond a single research result. NIH aimed to use this program to help turn the NCBC program into a wider, more connected national resource by funding external collaborators who could validate, disseminate, improve, and creatively apply NCBC-developed computational capabilities to concrete biomedical and behavioral research problems.

Is this opportunity still open for applications?

No. Based on the dates provided, the FOA is archived as of January 8, 2015, and the last listed closing date was January 7, 2015.

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