Opportunity Information: Apply for PA 15 123
Apply for PA 15 123
- The National Institutes of Health in the environment health sector is offering a public funding opportunity titled "Collaborative Activities to promote High Dimensional Molecular Analyses in NIEHS supported Childrens Environmental Health Studies (Admin Supp)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health.
- This funding opportunity was created on Feb 24, 2015 and posted on Feb 24, 2015.
- Applicants must submit their applications by Apr 6, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities City or township governments Native American tribal governments (Federally recognized) State governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
Collaborative Activities to Promote High Dimensional Molecular Analyses in NIEHS Supported Childrens Environmental Health Studies (Administrative Supplement), funding opportunity number PA-15-123, was a National Institutes of Health (NIH) discretionary grant opportunity administered as an administrative supplement mechanism. The purpose was to provide additional funds to investigators who already held active, awarded research grants so they could add to or strengthen ongoing work in high dimensional molecular analysis within existing pregnancy, birth, and/or childrens cohort studies supported by the National Institute of Environmental Health Sciences (NIEHS). In practical terms, the program was meant to accelerate and improve the use of modern "omics" and similar large-scale molecular profiling approaches in cohorts that were already collecting biospecimens and environmental health data, rather than creating new cohorts from scratch.
The scientific focus centered on collaborative activities that facilitate or enhance proteomics, metabolomics, epigenomics, and other high dimensional molecular analysis methods. These approaches can generate broad, information-rich datasets from biological samples (for example, blood, urine, saliva, placenta, cord blood, or other biospecimens often available in pregnancy and child health cohorts). By funding administrative supplements, NIEHS aimed to help existing childrens environmental health studies expand their ability to measure molecular signatures of exposure, susceptibility, and early biological response, and to link those signatures with environmental factors and health outcomes across critical developmental windows.
This opportunity fell under the Environment/Health activity category and was associated with CFDA number 93.113 (Environmental Health). It did not require cost sharing or matching. The estimated total funding amount listed for the opportunity was $5,000,000, with an award ceiling of $300,000 per supplement, indicating that the program was structured to provide moderate, targeted increments of support that could be attached to ongoing NIH-funded projects.
Eligibility was broad in terms of institutional types, reflecting NIH's general applicant landscape, and included public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, and a range of governmental bodies (state, county, city/township, special district governments, independent school districts, public housing authorities/Indian housing authorities), as well as Native American tribal governments and tribal organizations. Additional eligible applicant categories explicitly included several institution types and community-focused entities such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations and eligible federal agencies. At the same time, the announcement specified important limits related to foreign participation: non-U.S. entities (foreign organizations and foreign institutions) were not eligible to apply as applicant organizations, and non-U.S. components of U.S. organizations were not eligible to apply. However, foreign components as defined in the NIH Grants Policy Statement were allowed, meaning some internationally conducted elements could be included when compliant with NIH policy and justified scientifically.
Key dates in the lifecycle of the opportunity show it was posted and created on February 24, 2015, with an original and current closing date of April 6, 2015, and an archive date of May 7, 2015. As an administrative supplement announcement, it was intended for relatively quick, additive support tied to an existing award, enabling researchers to integrate new molecular assays, broaden analytic pipelines, or coordinate collaborative data generation and interpretation without the longer lead time associated with a brand-new multi-year competing grant.
For applicants and institutions seeking official details at the time, NIH provided an additional information link to the full announcement text hosted in the NIH Grants Guide: http://grants.nih.gov/grants/guide/pa-files/PA-15-123.html. The contact route listed for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Collaborative Activities to Promote High Dimensional Molecular Analyses in NIEHS Supported Childrens Environmental Health Studies (Administrative Supplement) (PA-15-123)
What is PA-15-123?
PA-15-123 was a National Institutes of Health (NIH) discretionary grant opportunity offered as an administrative supplement. It was focused on supporting collaborative activities that promote high dimensional molecular analyses (such as "omics") within existing NIEHS-supported childrens environmental health cohort studies.
Which NIH institute supported this opportunity?
The opportunity was supported by the National Institute of Environmental Health Sciences (NIEHS), part of NIH.
What was the purpose of this administrative supplement?
The purpose was to provide additional funds to investigators with active, awarded NIH research grants so they could add to or strengthen ongoing work involving high dimensional molecular analysis in existing pregnancy, birth, and/or childrens cohort studies supported by NIEHS.
What does "administrative supplement" mean in this context?
In this context, an administrative supplement was intended to provide relatively quick, additive support that could be attached to an existing NIH-funded project, rather than funding a brand-new standalone cohort or a new multi-year competing award.
Was this funding intended to create new cohort studies?
No. The program was designed to accelerate and improve the use of modern high dimensional molecular profiling approaches in cohorts that already existed and were already collecting biospecimens and environmental health data, rather than creating new cohorts from scratch.
What kinds of scientific activities were encouraged?
The scientific focus was on collaborative activities that facilitate or enhance proteomics, metabolomics, epigenomics, and other high dimensional molecular analysis methods, especially as applied to existing pregnancy and child health cohorts.
What is meant by "high dimensional molecular analyses"?
High dimensional molecular analyses refer to modern, large-scale molecular profiling approaches (often described as "omics") that can generate broad, information-rich datasets from biological samples, enabling researchers to study molecular signatures related to exposure, susceptibility, and early biological response.
What types of "omics" or molecular approaches were highlighted?
The opportunity specifically highlighted proteomics, metabolomics, and epigenomics, and also referenced other high dimensional molecular analysis methods.
What types of biospecimens could be relevant to this program?
Examples of biospecimens mentioned include blood, urine, saliva, placenta, cord blood, and other biospecimens commonly available in pregnancy and child health cohorts.
What kinds of questions or outcomes was this supplement meant to help study?
The supplement aimed to expand cohort capacity to measure molecular signatures of exposure, susceptibility, and early biological response, and to link those signatures with environmental factors and health outcomes across critical developmental windows.
What activity category was this opportunity associated with?
This opportunity fell under the Environment/Health activity category.
What CFDA number was associated with PA-15-123?
The opportunity was associated with CFDA number 93.113 (Environmental Health).
How much total funding was estimated for the opportunity?
The estimated total funding amount listed for the opportunity was $5,000,000.
What was the maximum award amount per supplement?
The award ceiling was $300,000 per supplement.
Did the opportunity require cost sharing or matching funds?
No. The announcement indicated that cost sharing or matching was not required.
Who was eligible to apply?
Eligibility included a wide range of applicant organization types consistent with NIH participation, including public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, and many types of governmental bodies.
Which government entities were listed as eligible applicants?
Eligible government entities included state, county, city/township, special district governments, independent school districts, public housing authorities/Indian housing authorities, as well as Native American tribal governments and tribal organizations. Eligible federal agencies were also included.
Were minority-serving institutions and community-focused organizations included in eligibility?
Yes. The eligibility categories explicitly included institutions and entities such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations.
Were foreign organizations eligible to apply as the applicant organization?
No. The announcement specified that non-U.S. entities (foreign organizations and foreign institutions) were not eligible to apply as applicant organizations.
Could a non-U.S. component of a U.S. organization apply?
No. The announcement stated that non-U.S. components of U.S. organizations were not eligible to apply.
Was any form of foreign involvement allowed?
Yes. Foreign components, as defined in the NIH Grants Policy Statement, were allowed. This means internationally conducted elements could be included when compliant with NIH policy and scientifically justified.
When was PA-15-123 posted and created?
The opportunity was posted and created on February 24, 2015.
What was the closing date for applications?
The original and current closing date listed was April 6, 2015.
When was the opportunity archived?
The archive date listed was May 7, 2015.
Where could applicants find the official full announcement text?
The full announcement text was hosted in the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-15-123.html.
Who was listed as a contact for access or linking issues?
The contact route listed for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What was the practical intent of the funding approach?
In practical terms, the program was meant to help existing NIEHS-supported pregnancy and child health cohorts integrate or expand modern molecular assays, broaden analytic pipelines, and coordinate collaborative data generation and interpretation without the longer lead time associated with starting a new cohort or applying for a new competing multi-year grant.
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