Opportunity Information: Apply for PA 14 003
Apply for PA 14 003
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Collaborative Activities to Promote Metabolomics Research (Admin Supp)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Nov 14, 2013 and posted on Nov 14, 2013.
- Applicants must submit their applications by Feb 14, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Independent school districts County governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) State governments City or township governments Public housing authorities/Indian housing authorities Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The grant opportunity "Collaborative Activities to Promote Metabolomics Research (Admin Supp)" (Funding Opportunity Number PA 14-003) is an NIH administrative supplement tied to the Common Fund Metabolomics Program, a national effort aimed at strengthening the United States' capacity to perform high-quality metabolomics work in translational and clinical research. The underlying premise is that metabolomics can be a powerful way to deepen understanding of human disease and biology, but it is also technically demanding and often outside the core expertise of many biomedical research teams. Because study design, analytical technology choices, and the downstream interpretation of metabolomics data require specialized knowledge, NIH designed this supplement to help existing NIH-funded projects add metabolomics components in a way that is both scientifically rigorous and educational for the parent research team.
This is not a standalone new grant mechanism; it is specifically an administrative supplement, meaning it provides additional funds to an already active NIH-funded parent award. The purpose is to support new, interactive collaborations between basic science or clinical researchers and metabolomics experts. In practical terms, the supplement is meant to enable a currently funded research project to incorporate metabolomics analyses that meaningfully extend the scope or impact of the original work. The expectation is that the metabolomics work is not just a fee-for-service add-on, but a genuine collaboration where metabolomics specialists contribute to the way samples are collected and handled, how experiments are structured, what platforms or assays are selected, and how results are processed, analyzed, and interpreted in a biomedical context.
A key requirement that stands out in the description is the emphasis on capacity-building within the applying biomedical research group. Beyond simply generating metabolomics data, the collaborative project must include activities that increase the parent team's expertise in the essentials of metabolomics. That includes improving understanding of metabolomics study design (such as issues around sample collection timing, confounders, batch effects, and quality control), strengthening competence in data analysis (such as preprocessing, normalization, statistics, and pathway or network approaches), and developing better interpretive skills (linking metabolite patterns to biology, disease mechanisms, and clinical outcomes). In other words, the supplement is designed to leave the biomedical team better equipped to use metabolomics correctly in future studies, not just to produce one additional dataset.
The opportunity is issued by the National Institutes of Health and categorized as discretionary grant funding within a health-focused activity area. It is associated with CFDA number 93.310 (Trans-NIH Research Support). No cost sharing or matching is required, which means applicants generally are not expected to provide a formal financial match as a condition of the award. The estimated total funding listed for the opportunity is $2,000,000, reflecting NIH's overall anticipated support level for awards made under this administrative supplement announcement.
Eligibility is broad and includes many organization types that commonly participate in NIH research. Eligible applicants include public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), small businesses, for-profit organizations other than small businesses, local and state government entities (such as county governments, city or township governments, special district governments), independent school districts, public housing authorities/Indian housing authorities, Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized), and a range of other entities described in the eligibility section. The eligibility language also explicitly includes various institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribal Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. Importantly, non-U.S. entities are also eligible: foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed. This reflects NIH's interest in supporting strong metabolomics collaborations wherever the necessary expertise and scientific opportunity exist, provided the work aligns with NIH policy and the parent award is eligible for supplementation.
From a timeline standpoint, the opportunity was posted and created on November 14, 2013, with an original and current closing date of February 14, 2014, and an archive date of March 17, 2014. While those dates indicate this particular announcement is historical, the structure is representative of how NIH administrative supplements are often used to rapidly expand existing projects into strategically important areas, especially when specialized expertise is a limiting factor.
For applicants looking for the full official announcement and requirements, NIH provided an additional information link to the FOA page (http://grants.nih.gov/grants/guide/pa-files/PA-14-003.html). For technical difficulties accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Collaborative Activities to Promote Metabolomics Research (Administrative Supplement) (PA 14-003)
What is the "Collaborative Activities to Promote Metabolomics Research (Admin Supp)" opportunity?
It is an NIH administrative supplement opportunity tied to the Common Fund Metabolomics Program. Its goal is to help existing NIH-funded research projects add scientifically rigorous metabolomics components through interactive collaborations with metabolomics experts.
Is PA 14-003 a standalone grant or a supplement?
It is not a standalone new grant mechanism. It is an administrative supplement, meaning it provides additional funds to an already active NIH-funded parent award.
What is the main purpose of this administrative supplement?
The purpose is to support new, interactive collaborations between basic science or clinical researchers and metabolomics experts so that an ongoing NIH-funded project can incorporate metabolomics analyses that meaningfully extend the original work.
What is the underlying rationale for focusing on metabolomics?
The premise is that metabolomics can deepen understanding of human disease and biology, but it is technically demanding and often outside the core expertise of many biomedical research teams. Specialized knowledge is needed for study design, technology choices, and interpretation.
What kind of collaboration does NIH expect under this supplement?
NIH expects a genuine, interactive collaboration, not a simple fee-for-service arrangement. Metabolomics specialists are expected to contribute to decisions about sample collection and handling, experimental structure, platform or assay selection, and how results are processed, analyzed, and interpreted in a biomedical context.
How should the metabolomics component relate to the parent award?
The metabolomics work is intended to be incorporated into a currently funded research project in a way that meaningfully extends the scope or impact of the original work.
Does the supplement emphasize education or capacity-building for the parent research team?
Yes. A key requirement is capacity-building within the applying biomedical research group. The collaborative project must include activities that increase the parent team’s expertise in the essentials of metabolomics, so the team is better equipped to use metabolomics correctly in future studies.
What specific metabolomics skills should the parent team build through this supplement?
The description highlights improvements in (1) metabolomics study design (including sample collection timing, confounders, batch effects, and quality control), (2) data analysis competence (including preprocessing, normalization, statistics, and pathway or network approaches), and (3) interpretive skills (linking metabolite patterns to biology, disease mechanisms, and clinical outcomes).
Is generating metabolomics data the only goal?
No. Beyond generating metabolomics data, the project should strengthen the parent team’s knowledge and ability to design, analyze, and interpret metabolomics studies appropriately.
Which NIH program is this supplement tied to?
It is tied to the NIH Common Fund Metabolomics Program, described as a national effort to strengthen U.S. capacity to perform high-quality metabolomics work in translational and clinical research.
Who is issuing this funding opportunity?
The opportunity is issued by the National Institutes of Health (NIH).
How is this opportunity categorized?
It is categorized as discretionary grant funding within a health-focused activity area.
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA 93.310 (Trans-NIH Research Support).
Is cost sharing or matching required?
No cost sharing or matching is required, meaning applicants generally are not expected to provide a formal financial match as a condition of the award.
How much total funding is estimated for this opportunity?
The estimated total funding listed is $2,000,000, reflecting NIH’s overall anticipated support level for awards made under this administrative supplement announcement.
Which organizations are eligible to apply?
Eligibility is broad. Eligible applicants include public and private institutions of higher education, nonprofits (with and without 501(c)(3) status), small businesses, for-profit organizations other than small businesses, and various state and local government entities (including county and city or township governments and special district governments). Independent school districts, public housing authorities/Indian housing authorities, and other entities described in the eligibility section are also included.
Are tribal governments and tribal organizations eligible?
Yes. Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized) are explicitly included in the eligibility language.
Are specific institution types like HBCUs or Hispanic-serving institutions eligible?
Yes. The eligibility language explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribal Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly included as eligible applicants.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are included in the eligibility language.
Can non-U.S. (foreign) organizations apply?
Yes. Foreign organizations and foreign institutions may apply. In addition, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed.
Why does the FOA allow foreign entities and components?
The description indicates NIH’s interest in supporting strong metabolomics collaborations wherever the necessary expertise and scientific opportunity exist, provided NIH policy is followed and the parent award is eligible for supplementation.
What are the key dates for this opportunity?
The opportunity was posted/created on November 14, 2013. The original and current closing date was February 14, 2014. The archive date was March 17, 2014.
Is this funding opportunity still open?
Based on the provided dates (closing date February 14, 2014 and archive date March 17, 2014), this particular announcement is historical rather than currently open.
Where can applicants find the official FOA and full requirements?
NIH provided an official FOA page link: http://grants.nih.gov/grants/guide/pa-files/PA-14-003.html
Who should be contacted for technical difficulties accessing or linking to the announcement?
The listed contact for technical difficulties is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the Funding Opportunity Number for this administrative supplement?
The Funding Opportunity Number is PA 14-003.
What types of research teams is this supplement meant to help?
It is meant to help basic science or clinical research teams that have an active NIH-funded project and want to incorporate metabolomics in a way that is technically sound, scientifically rigorous, and educational for the parent team.
What kinds of metabolomics-related decisions are expected to involve the metabolomics experts?
The description specifically notes involvement in sample collection and handling, experiment structure, platform or assay selection, and downstream processing, analysis, and interpretation of metabolomics results.
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