Opportunity Information: Apply for PA 15 030

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Collaborative Activities to Promote Metabolomics Research (Admin Supp)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
  • This funding opportunity was created on Nov 5, 2014 and posted on Nov 5, 2014.
  • Applicants must submit their applications by Feb 13, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • Eligible applicants include: Small businesses City or township governments Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

Collaborative Activities to Promote Metabolomics Research (Admin Supp) (PA 15-030) is an NIH administrative supplement opportunity under the NIH Common Fund Metabolomics Program. Its main purpose is to strengthen the nation's capacity to carry out high-quality metabolomics studies within translational and clinical research, recognizing that metabolomics can significantly deepen understanding of human disease but often demands specialized knowledge in study design, measurement technologies, and complex data analysis and interpretation.

The supplement is designed specifically for investigators who already hold active NIH-funded awards and want to extend the scientific scope of their existing, parent project by adding a metabolomics component. Rather than funding a stand-alone, new project, the mechanism provides additional funds to support a new, interactive collaboration between the parent-grant research team (basic and/or clinical researchers) and metabolomics experts. The expectation is that metabolomics methods will be integrated into the existing Research Strategy of the parent grant in a way that meaningfully enhances the original aims, for example by incorporating metabolite profiling, targeted or untargeted assays, metabolomics-informed biomarkers, or metabolomics-driven insights into disease mechanisms or treatment response.

A central requirement is that the collaboration must go beyond simply purchasing a service or generating a dataset. The proposed activities must also build capacity and expertise within the biomedical research group by improving their competence in key elements of metabolomics, including proper metabolomics study design (such as sampling strategies, controls, and handling of biological variability), analysis approaches, and interpretation of metabolomics results. In other words, the supplement is meant to create a two-way partnership that transfers knowledge and improves future readiness to use metabolomics thoughtfully and rigorously, not just to add an extra data layer.

The funding opportunity was posted on November 5, 2014, with an application due date of February 13, 2015, and it was archived on March 16, 2015. NIH estimated total funding for the program at approximately $2,000,000, with an award ceiling of $100,000 per supplement request, and it does not require cost sharing or matching. The activity category is health, and it is associated with CFDA 93.310 (Trans-NIH Research Support).

Eligibility is broad and includes many organization types that can hold NIH grants, spanning public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses), and a wide range of government entities (state, county, city/township, special district, and others). It also explicitly includes Tribal governments and Tribal organizations, U.S. territories or possessions, regional organizations, faith-based and community-based organizations, and designated institution types such as HBCUs, HSIs, TCCUs, Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs. Importantly, non-U.S. entities are eligible as well: foreign organizations and foreign institutions may apply, foreign components are allowed as defined by the NIH Grants Policy Statement, and non-domestic components of U.S. organizations are also eligible.

NIH strongly encourages potential applicants to discuss their supplement plans in advance with both the NIH Institute or Center (IC) that funds the parent award and the Common Fund Metabolomics scientific/research contact associated with the announcement. This pre-application communication is intended to confirm fit with program priorities, ensure the request is appropriate for an administrative supplement, and help align the metabolomics collaboration and training/capacity-building elements with NIH expectations. Further details were provided through the NIH program page linked in the announcement (http://grants.nih.gov/grants/guide/pa-files/PA-15-030.html), with NIH Office of Extramural Research (OER) support contacts listed for access or technical linking issues.

Frequently Asked Questions (FAQs)

What is the Collaborative Activities to Promote Metabolomics Research (Admin Supp) opportunity (PA 15-030)?

PA 15-030 is an NIH administrative supplement opportunity under the NIH Common Fund Metabolomics Program. It is intended to strengthen the nation's capacity to conduct high-quality metabolomics studies within translational and clinical research by supporting collaborative activities that add metabolomics expertise and methods to an existing NIH-funded project.

What is the main goal of this administrative supplement?

The main goal is to enhance translational and clinical research by integrating metabolomics in a way that meaningfully deepens understanding of human disease. The supplement supports both the scientific addition (a metabolomics component) and the capacity-building needed to use metabolomics rigorously, including study design, measurement approaches, and complex data analysis and interpretation.

Is this funding for a new, stand-alone research project?

No. This mechanism is specifically for adding funds to an active, NIH-funded parent award. It is designed to extend the scientific scope of the existing parent project by incorporating a metabolomics component, rather than creating a separate, stand-alone project.

Who is this supplement intended for?

It is intended for investigators who already hold an active NIH-funded award and want to expand their parent project by adding metabolomics work through a new, interactive collaboration with metabolomics experts.

What kinds of collaborations does the supplement support?

The supplement supports interactive collaborations between the parent-grant research team (basic and/or clinical researchers) and metabolomics experts, with the expectation that knowledge is shared and metabolomics is integrated thoughtfully into the parent project.

Does the collaboration need to be more than a fee-for-service arrangement?

Yes. A central requirement is that the collaboration must go beyond simply purchasing a service or generating a dataset. The activities should create a two-way partnership that transfers knowledge and builds metabolomics competence within the parent project team.

What capacity-building or training expectations are included in this supplement?

The supplement is intended to improve the biomedical research group's competence in key elements of metabolomics. Examples described in the opportunity include improving metabolomics study design (such as sampling strategies, controls, and handling biological variability), strengthening analysis approaches, and improving interpretation of metabolomics results.

How should metabolomics be incorporated into the parent project?

Metabolomics methods are expected to be integrated into the existing Research Strategy of the parent grant in a way that enhances the original aims. The metabolomics component should meaningfully extend the scientific scope of the parent award rather than being an add-on that does not affect the direction or rigor of the research.

What are examples of metabolomics activities that might be added to a parent grant?

Examples mentioned include incorporating metabolite profiling, using targeted or untargeted assays, developing or applying metabolomics-informed biomarkers, or generating metabolomics-driven insights into disease mechanisms or treatment response.

What types of research does this opportunity emphasize?

The opportunity emphasizes metabolomics work in the context of translational and clinical research, recognizing that metabolomics can deepen understanding of human disease but often requires specialized expertise in study design, measurement technologies, and data analysis and interpretation.

How much funding is available per supplement?

The award ceiling is $100,000 per supplement request.

What was the estimated total funding level for the program?

NIH estimated total funding at approximately $2,000,000 for the program.

Is cost sharing or matching required?

No. The opportunity does not require cost sharing or matching.

When was the opportunity posted, and what were the key dates?

The funding opportunity was posted on November 5, 2014. The application due date was February 13, 2015. The opportunity was archived on March 16, 2015.

What does it mean that the opportunity is archived?

Based on the information provided, the announcement was archived on March 16, 2015, meaning it is no longer an active, open solicitation under that posting.

What is the activity category for this opportunity?

The activity category is health.

What CFDA number is associated with this opportunity?

The opportunity is associated with CFDA 93.310 (Trans-NIH Research Support).

What types of organizations are eligible to apply?

Eligibility is broad and includes many organization types that can hold NIH grants, including public and private institutions of higher education; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses); and a wide range of government entities (state, county, city/township, special district, and others).

Are Tribal governments and Tribal organizations eligible?

Yes. Tribal governments and Tribal organizations are explicitly included as eligible.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are listed as eligible.

Are faith-based and community-based organizations eligible?

Yes. Faith-based and community-based organizations are explicitly included.

Are minority-serving institutions included in the eligible organization types?

Yes. The eligibility list explicitly includes designated institution types such as HBCUs, HSIs, TCCUs, Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs.

Are foreign (non-U.S.) organizations eligible to apply?

Yes. Non-U.S. entities are eligible. Foreign organizations and foreign institutions may apply. Foreign components are allowed as defined by the NIH Grants Policy Statement, and non-domestic components of U.S. organizations are also eligible.

Does NIH recommend contacting anyone before applying?

Yes. NIH strongly encourages potential applicants to discuss supplement plans in advance with both (1) the NIH Institute or Center (IC) that funds the parent award and (2) the Common Fund Metabolomics scientific/research contact associated with the announcement.

Why is pre-application communication encouraged?

Pre-application communication is intended to confirm fit with program priorities, ensure the request is appropriate for an administrative supplement, and help align the proposed metabolomics collaboration and capacity-building elements with NIH expectations.

Where can applicants find the official announcement information?

Further details were provided through the NIH program page linked in the announcement: http://grants.nih.gov/grants/guide/pa-files/PA-15-030.html

Who should be contacted for access or technical linking issues?

NIH Office of Extramural Research (OER) support contacts were listed for access or technical linking issues, according to the opportunity description.

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