Opportunity Information: Apply for RFA AG 16 009
Apply for RFA AG 16 009
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Collaborative Networks to Advance Delirium Research (R24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on May 27, 2015 and posted on May 27, 2015.
- Applicants must submit their applications by Jan 12, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $750,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Native American tribal governments (Federally recognized) County governments Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses Private institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH funding opportunity "Collaborative Networks to Advance Delirium Research (R24)" (RFA-AG-16-009) was a discretionary grant program in the health area, administered under CFDA 93.866 (Aging Research). Its purpose was to fund a single, coordinated collaborative network focused on improving and accelerating scientific progress in delirium research in older adults. Delirium is described in the announcement as an acute impairment of cognition and attention that commonly occurs during severe illness and after surgery, particularly in older populations, and it is linked with serious downstream consequences such as higher morbidity and mortality, loss of function, cognitive decline, and increased likelihood of institutionalization. A key motivation for the program is that delirium is still substantially underdiagnosed, and the field continues to face major gaps in understanding the biology and mechanisms of delirium, how to predict outcomes (prognosis), and how best to prevent or treat it. The announcement also highlights evidence suggesting delirium may be meaningfully preventable, citing multicomponent intervention studies indicating roughly 30 to 40 percent preventability, which underscores the potential payoff of better coordinated research.
The core intent of this R24 mechanism was not simply to support isolated projects, but to build or strengthen a networked research infrastructure that could move the field forward more efficiently. The network was expected to advance research spanning causes, mechanisms, outcomes, diagnosis, prevention, and treatment of delirium in older adults. In practice, an R24 network award typically emphasizes collaboration, shared resources, harmonized approaches, and field-building activities that allow multiple investigators or sites to work toward common standards and priorities, rather than each group reinventing methods independently. The underlying logic is that delirium research has cross-cutting needs (for example, improving detection and assessment, aligning definitions and measures, and enabling studies that link clinical presentation to mechanisms and long-term outcomes) that are difficult to solve without deliberate coordination across teams and settings.
From a funding and administrative standpoint, the opportunity anticipated one award, with an estimated total funding level of $750,000 and an award ceiling of $500,000. The opportunity did not require cost sharing or matching. It was posted on May 27, 2015, with an original and final application closing date of January 12, 2016, and it was later archived on February 12, 2016. Although the program is now archived, the summary details are still useful for understanding the NIH’s priorities in delirium research and the type of collaborative structure NIH was seeking to support at the time.
Eligibility was broad and included many types of U.S.-based organizations and governments. Eligible applicants included public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations), for-profit organizations other than small businesses, small businesses, state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and federally recognized tribal governments as well as other tribal organizations. The announcement also explicitly listed additional eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations were not eligible to apply, though foreign components (as defined by NIH policy) were allowed, which generally means a U.S. applicant could include certain foreign elements when well-justified and compliant with NIH rules.
The sponsoring agency was the National Institutes of Health. The full announcement was available via the NIH Grants Guide at the link provided in the notice (http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-16-009.html). For technical issues accessing the announcement, the contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: NIH "Collaborative Networks to Advance Delirium Research (R24)" (RFA-AG-16-009)
What is this funding opportunity?
This was an NIH funding opportunity titled "Collaborative Networks to Advance Delirium Research (R24)" with opportunity number RFA-AG-16-009. It was a discretionary grant program in the health area administered under CFDA 93.866 (Aging Research).
What was the purpose of the program?
The purpose was to fund a single, coordinated collaborative network focused on improving and accelerating scientific progress in delirium research in older adults. The emphasis was on building or strengthening a networked research infrastructure rather than supporting isolated, stand-alone projects.
What topic area did the announcement focus on?
The announcement focused on delirium research in older adults, including research spanning causes, mechanisms, outcomes, diagnosis, prevention, and treatment.
How did the announcement define delirium?
Delirium was described as an acute impairment of cognition and attention that commonly occurs during severe illness and after surgery, particularly in older populations.
Why did NIH consider delirium an important research priority in this opportunity?
The announcement highlighted that delirium is linked with serious downstream consequences, including higher morbidity and mortality, loss of function, cognitive decline, and increased likelihood of institutionalization. It also emphasized that delirium remains substantially underdiagnosed and that major gaps persist in understanding its biology/mechanisms, predicting outcomes (prognosis), and determining the best approaches to prevention and treatment.
Did the announcement suggest delirium might be preventable?
Yes. The announcement cited multicomponent intervention studies indicating that delirium may be roughly 30 to 40 percent preventable, underscoring the potential payoff of better coordinated research.
What does the R24 mechanism emphasize in this program?
In this context, the R24 mechanism was intended to support a collaborative network and research infrastructure that could move the field forward more efficiently. It typically implies collaboration, shared resources, harmonized approaches, and field-building activities so investigators or sites can work toward common standards and priorities rather than developing methods independently.
Was the intent to fund multiple independent research projects?
No. The core intent was not to fund isolated projects, but to establish or strengthen a coordinated network that could address cross-cutting needs in delirium research through deliberate coordination across teams and settings.
What kinds of research areas was the network expected to advance?
The network was expected to advance research spanning the causes, mechanisms, outcomes, diagnosis, prevention, and treatment of delirium in older adults.
How many awards were anticipated?
The opportunity anticipated one award.
How much funding was available?
The opportunity listed an estimated total funding level of $750,000 and an award ceiling of $500,000.
Was cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
When was the opportunity posted and when did it close?
It was posted on May 27, 2015. The original and final application closing date was January 12, 2016.
Is this funding opportunity still open?
No. The opportunity was later archived on February 12, 2016.
Who administered and sponsored this opportunity?
The sponsoring agency was the National Institutes of Health (NIH). It was administered under CFDA 93.866 (Aging Research).
Who was eligible to apply?
Eligibility was broad and included many types of U.S.-based organizations and governments. Eligible applicants included:
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations)
- For-profit organizations other than small businesses
- Small businesses
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public housing authorities/Indian housing authorities
- Federally recognized tribal governments and other tribal organizations
- U.S. territories or possessions
- Eligible federal agencies
- Faith-based or community-based organizations
- Regional organizations
Were minority-serving institutions specifically mentioned as eligible?
Yes. The announcement explicitly listed eligibility for institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Could a non-U.S. (foreign) institution apply as the applicant?
No. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations were not eligible to apply as applicants under this opportunity.
Were any foreign elements allowed at all?
Yes. While foreign institutions could not apply as the applicant, foreign components (as defined by NIH policy) were allowed. This generally means a U.S. applicant could include certain foreign elements when well-justified and compliant with NIH rules.
Where could applicants find the full announcement?
The full announcement was available via the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-16-009.html
Who was the contact for technical issues accessing the announcement?
For technical issues accessing the announcement, the contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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