Opportunity Information: Apply for RFA HD 14 022

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Collaborative Pediatric Critical Care Research Network (UG1)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Mar 20, 2014 and posted on Mar 19, 2014.
  • Applicants must submit their applications by Jun 2, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,800,000.00 to eligible and selected applicants.
  • Eligible applicants include: For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) County governments State governments Special district governments City or township governments Native American tribal governments (Federally recognized) Independent school districts.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Apply for RFA HD 14 022

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Opportunity Summary:

The Collaborative Pediatric Critical Care Research Network (CPCCRN) (UG1) funding opportunity, RFA-HD-14-022, was issued by the National Institutes of Health (NIH) through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It supports a multi-center research network focused on pediatric critical care, specifically by funding institutions to function as Clinical Sites within CPCCRN. The overall purpose is to strengthen and coordinate rigorous, multi-site clinical research that can improve outcomes for critically ill and injured children. The network is intended to generate evidence on how best to treat and manage pediatric critical illness and injury, while also advancing scientific understanding of the underlying pathophysiology that drives these conditions in childhood.

This announcement uses a cooperative agreement mechanism (UG1), which typically means the funded sites are not operating independently in isolation, but instead working in close coordination with NICHD and the network leadership under a shared framework. In practice, that implies expectations around collaboration, protocol harmonization across sites, consistent data collection practices, and active participation in network-wide studies. The emphasis is on clinical research that is difficult to accomplish in a single institution, such as studies requiring large sample sizes, diverse patient populations, or standardized implementation across multiple pediatric intensive care environments.

From a programmatic standpoint, the FOA sits within the Health activity area and is associated with CFDA 93.865 (Child Health and Human Development Extramural Research). The opportunity did not require cost sharing or matching. NIH estimated total funding of about $1.8 million for this announcement, reflecting support aimed at establishing and/or maintaining multiple participating clinical sites as part of a coordinated national research effort in pediatric critical care.

Eligibility was broad across U.S.-based organizations and government entities, including public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses), and a wide range of governmental units such as state, county, city/township, special district governments, and independent school districts. The FOA also explicitly included several institution types and community-focused or mission-driven entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Foreign institutions were not eligible, and foreign components or non-U.S. components of U.S. organizations were not allowed under NIH policy for this opportunity.

Key timeline details include a posted date of March 19, 2014, with an original and current application due date of June 2, 2014, and an archive date of July 3, 2014. The full announcement was made available through the NIH Grants Guide, and the FOA provided support contacts through the NIH Office of Extramural Research (OER) for access or technical linking issues.

Frequently Asked Questions (FAQs)

1) What is the funding opportunity called?

The opportunity is the Collaborative Pediatric Critical Care Research Network (CPCCRN) (UG1) funding opportunity, referenced as RFA-HD-14-022.

2) Which federal agency and institute issued this FOA?

It was issued by the National Institutes of Health (NIH) through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

3) What is the overall purpose of this program?

The purpose is to strengthen and coordinate rigorous, multi-site clinical research to improve outcomes for critically ill and injured children. The network is intended to generate evidence on how best to treat and manage pediatric critical illness and injury and to advance scientific understanding of the underlying pathophysiology driving these conditions in childhood.

4) What type of organizations are being funded under this announcement?

The FOA supports institutions to function as Clinical Sites within the Collaborative Pediatric Critical Care Research Network (CPCCRN).

5) What does it mean that this award uses a UG1 cooperative agreement mechanism?

The UG1 cooperative agreement mechanism indicates that funded sites are expected to work in close coordination with NICHD and network leadership rather than operating independently. This implies expectations around collaboration, protocol harmonization across sites, consistent data collection practices, and active participation in network-wide studies.

6) What kinds of research activities does the network emphasize?

The emphasis is on clinical research that is difficult to accomplish at a single institution, such as studies requiring large sample sizes, diverse patient populations, or standardized implementation across multiple pediatric intensive care environments.

7) What activity area is this FOA associated with?

From a programmatic standpoint, the FOA sits within the Health activity area.

8) What CFDA number is associated with this opportunity?

This opportunity is associated with CFDA 93.865, Child Health and Human Development Extramural Research.

9) Is cost sharing or matching required?

No. The opportunity did not require cost sharing or matching.

10) What was the estimated total funding amount for this announcement?

NIH estimated total funding of about $1.8 million for this announcement, reflecting support aimed at establishing and/or maintaining multiple participating clinical sites as part of a coordinated national pediatric critical care research effort.

11) Who was eligible to apply?

Eligibility was broad across U.S.-based organizations and government entities, including public and private institutions of higher education, nonprofit organizations (with and without 501(c)(3) status), for-profit organizations (including small businesses), and many governmental units (state, county, city/township, special district governments, and independent school districts).

12) Are minority-serving institutions included in the eligible applicant types?

Yes. The FOA explicitly included institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

13) Are faith-based or community-based organizations eligible?

Yes. The FOA explicitly included faith-based or community-based organizations among eligible applicants.

14) Are regional organizations eligible to apply?

Yes. Regional organizations were listed among eligible applicant types.

15) Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions were explicitly included among eligible applicant types.

16) Are federal agencies eligible to apply?

Yes. Eligible federal agencies were included as eligible applicants.

17) Are foreign institutions eligible to apply?

No. Foreign institutions were not eligible for this opportunity.

18) Are foreign components or non-U.S. components of U.S. organizations allowed?

No. Foreign components or non-U.S. components of U.S. organizations were not allowed under NIH policy for this opportunity.

19) When was the FOA posted?

The posted date was March 19, 2014.

20) What was the application due date?

The original and current application due date was June 2, 2014.

21) When was the FOA archived?

The archive date was July 3, 2014.

22) Where was the full announcement made available?

The full announcement was made available through the NIH Grants Guide.

23) Who should applicants contact for access or technical linking issues?

The FOA provided support contacts through the NIH Office of Extramural Research (OER) for access or technical linking issues.

24) What does "multi-center research network" mean in the context of CPCCRN?

In this context, it means CPCCRN is designed to coordinate research across multiple clinical sites rather than relying on a single hospital or institution, enabling studies that benefit from larger combined patient pools, broader geographic representation, and standardized approaches across pediatric intensive care settings.

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Previous opportunity: Data Coordinating Center for the Collaborative Pediatric Critical Care Research Network (U01)

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