Opportunity Information: Apply for RFA HS 14 011

  • The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Comparative Health System Performance in Accelerating PCOR Dissemination (U19)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes.
  • This funding opportunity was created on Jun 25, 2014 and posted on Jun 25, 2014.
  • Applicants must submit their applications by Oct 17, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $10,500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $3,500,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Native American tribal governments (Federally recognized) Private institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments.
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Faith based or Community based Organizations Indian/Native American Tribal Governments (Other than Federally Recognized) Because the purpose of this program is to improve healthcare in the United States, foreign institutions may participate in projects as members of consortia or as subcontractors only. Applications submitted by foreign institutions will not be reviewed. Organizations described in section 501(c) 4 of the Internal Revenue Code that engage in lobbying are not eligible. HHS grants policy requires that the grant recipient perform a substantive role in the conduct of the planned project or program activity and not merely serve as a conduit of funds to another party or parties. If consortium/contractual activities represent a significant portion of the overall project, the applicant must justify why the applicant organization, rather than the party(s) performing this portion of the overall project, should be the grantee and what substantive role the applicant organization will play. Justification can be provided in the Specific Aims or Research Strategy section of the PHS398 Research Plan Component sections of the SF424 (RandR) application. There is no budget allocation guideline for determining substantial involvement determination of substantial involvement is based on a review of the primary project activities for which grant support is provided and the organization(s) that will be performing those activities.
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Opportunity Summary:

The Agency for Healthcare Research and Quality (AHRQ) issued this Funding Opportunity Announcement (RFA HS-14-011) to support a small number of Centers of Excellence focused on comparative health system performance as a way to speed up dissemination of patient-centered outcomes research (PCOR) and other comparative effectiveness research (CER) findings. The core idea is to look across U.S. healthcare delivery systems (for example, integrated delivery systems, large multi-site provider organizations, and Accountable Care Organizations) and build a practical, evidence-driven way to identify and categorize these systems, track how they function over time, and compare how quickly and effectively they adopt CER-recommended practices. The emphasis is not just on producing research papers, but on generating usable knowledge about which system characteristics and operating conditions are associated with faster adoption and wider diffusion of evidence-based practices.

The award mechanism is a U19 cooperative agreement, which typically signals substantial involvement by the funding agency in shaping or coordinating the work as it proceeds. In plain terms, awardees would be expected to collaborate closely with AHRQ and potentially with each other, rather than operating as completely independent grantees. The program is positioned as part of AHRQ's broader PCOR dissemination efforts, so the deliverables are meant to strengthen the national capacity to move research evidence into routine care more quickly, with a focus on real-world healthcare systems as the unit of analysis and action.

Funding for the opportunity was planned at an estimated total of $10.5 million, with an expectation of up to three awards. The ceiling listed per award is $3.5 million. There is no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds to be eligible or competitive. The opportunity was posted on June 25, 2014, with an application due date of October 17, 2014, and it later moved into archive status on November 17, 2014. The CFDA number associated with the program is 93.226 (Research on Healthcare Costs, Quality and Outcomes), which fits the focus on performance, quality, and system-level outcomes.

Eligibility was broad across U.S.-based entities that can carry out substantial project work, including state governments, county governments, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized tribal governments, and other tribal organizations. The announcement also notes that certain other organizations could be eligible, including specific eligible federal agencies as well as faith-based or community-based organizations, as long as they meet the program and HHS grant policy requirements. Foreign institutions could not apply as the primary applicant and would not be reviewed if they did; however, they could participate as part of a consortium or as subcontractors, reflecting the program's U.S. healthcare improvement purpose. The FOA also explicitly excludes 501(c)(4) organizations that engage in lobbying, and it reinforces a key HHS policy point: the recipient organization must play a substantive role in the project and cannot simply pass funds through to other partners. If a large portion of the work would be done by consortium members or contractors, the application needed to justify why the applicant should be the grantee and clearly describe the applicant's direct responsibilities and contributions.

Overall, the opportunity aimed to build an organized, comparable picture of how different healthcare delivery systems perform when it comes to taking up CER findings and spreading them within and across systems. By identifying and tracking system types and characteristics, and by comparing adoption and diffusion patterns, AHRQ's intent was to help the field understand what accelerates implementation at scale and what slows it down, ultimately making it easier for evidence-based practices to reach patients faster through the organizations that deliver care. For full details, AHRQ directed applicants to the official FOA page hosted through the NIH Office of Extramural Research.

Frequently Asked Questions (FAQs)

What is this funding opportunity trying to accomplish?

This AHRQ Funding Opportunity Announcement (RFA HS-14-011) is designed to support a small number of Centers of Excellence focused on comparative health system performance. The goal is to speed up dissemination of patient-centered outcomes research (PCOR) and other comparative effectiveness research (CER) findings by learning, in practical terms, how U.S. healthcare delivery systems adopt and spread evidence-based practices.

What kind of projects is AHRQ looking to fund under this FOA?

The emphasis is on building a real-world, evidence-driven approach to identify and categorize U.S. healthcare delivery systems, track how they function over time, and compare how quickly and effectively they adopt CER-recommended practices. The intent is to generate usable knowledge about which system characteristics and operating conditions are linked to faster adoption and broader diffusion of evidence-based practices, not just to produce academic publications.

What is meant by "comparative health system performance" in this announcement?

In this context, it means looking across different healthcare delivery systems and comparing how they perform specifically in adopting and spreading CER/PCOR-supported practices. Performance is framed around uptake and diffusion of evidence-based practices within and across systems, and how that changes over time.

What types of healthcare delivery systems are in scope?

The announcement highlights U.S. healthcare delivery systems such as integrated delivery systems, large multi-site provider organizations, and Accountable Care Organizations (ACOs) as examples of the kinds of systems to examine and compare.

What is the main "unit of analysis" for this program?

The program focuses on real-world healthcare delivery systems as the unit of analysis and action, rather than focusing only on individual clinicians or single facilities.

How does this program relate to PCOR and CER dissemination?

This FOA is positioned as part of AHRQ's broader PCOR dissemination efforts. The expected deliverables are meant to strengthen national capacity to move research evidence into routine care faster by understanding adoption and diffusion in real delivery systems.

What funding mechanism is used for these awards?

The award mechanism is a U19 cooperative agreement.

What does a U19 cooperative agreement imply for how the work will be carried out?

A U19 cooperative agreement typically indicates substantial involvement by the funding agency during the project. In practical terms, awardees should expect to collaborate closely with AHRQ (and potentially with other awardees) rather than operating as fully independent grantees.

How much funding was planned for this opportunity overall?

The planned estimated total funding was $10.5 million.

How many awards were expected?

AHRQ expected to make up to three awards.

What was the maximum funding level per award?

The ceiling listed per award was $3.5 million.

Was cost sharing or matching required?

No. The FOA states there was no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds to be eligible or competitive.

What is the CFDA number for this opportunity and what does it relate to?

The CFDA number is 93.226, titled "Research on Healthcare Costs, Quality and Outcomes." This aligns with the FOA's focus on healthcare system performance, quality, and system-level outcomes.

When was the opportunity posted and when were applications due?

The opportunity was posted on June 25, 2014. The application due date was October 17, 2014.

What does it mean that the opportunity moved to archive status?

The FOA later moved into archive status on November 17, 2014, indicating it is no longer an active solicitation for new applications under that announcement.

Who was eligible to apply?

Eligibility was broad for U.S.-based entities capable of substantial project work, including state governments, county governments, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized tribal governments, and other tribal organizations.

Are faith-based or community-based organizations eligible?

The announcement notes that faith-based or community-based organizations could be eligible as long as they meet the program requirements and HHS grants policy requirements.

Could federal agencies apply?

The announcement indicates that certain eligible federal agencies could be eligible to apply, subject to the program and HHS policy requirements described in the FOA.

Are foreign institutions allowed to apply as the primary applicant?

No. Foreign institutions could not apply as the primary applicant and would not be reviewed if they did.

Can foreign institutions participate in any way?

Yes. The FOA states that foreign institutions could participate as part of a consortium or as subcontractors, consistent with the program's U.S. healthcare improvement purpose.

Are any types of organizations explicitly excluded?

Yes. The FOA explicitly excludes 501(c)(4) organizations that engage in lobbying.

Does the applicant organization need to do substantive work itself?

Yes. A key HHS policy point emphasized in the FOA is that the recipient organization must play a substantive role in the project and cannot simply pass funds through to other partners.

What if a large portion of the work is planned to be performed by consortium members or contractors?

The FOA indicates that if a large portion of the work would be done by consortium members or contractors, the application needed to justify why the applicant should be the grantee and clearly describe the applicant's direct responsibilities and contributions.

What kinds of outputs or deliverables does AHRQ appear to prioritize?

Based on the description, AHRQ prioritizes practical, usable knowledge that helps explain which system characteristics and operating conditions speed or slow adoption and diffusion of evidence-based practices. The emphasis is on accelerating implementation at scale in real healthcare delivery systems, not solely on generating research papers.

Where were applicants directed to find full official details?

AHRQ directed applicants to the official FOA page hosted through the NIH Office of Extramural Research.

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