Opportunity Information: Apply for RFA AG 13 005
Apply for RFA AG 13 005
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Comparative Physiological Studies of Aging (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Jul 20, 2012 and posted on Jul 20, 2012.
- Applicants must submit their applications by Oct 19, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- Eligible applicants include: Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public housing authorities/Indian housing authorities County governments Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Small businesses For profit organizations other than small businesses Public and State controlled institutions of higher education State governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Comparative Physiological Studies of Aging (R03) funding opportunity (RFA-AG-13-005) is a National Institutes of Health (NIH) discretionary grant program focused on aging research (CFDA 93.866). Its central goal is to encourage small, targeted projects that use comparative biology to explain why different vertebrate species age at different rates and show different patterns of lifespan and healthspan. In practical terms, the FOA is aimed at research that compares species to uncover molecular pathways and physiological mechanisms that may drive slower aging, longer life, or extended periods of good health, with the broader intent of sharpening scientific understanding of aging processes that could inform future biomedical strategies.
The scientific emphasis is on “comparative approaches,†meaning applicants are expected to leverage differences across vertebrate species rather than studying aging in a single model in isolation. The FOA explicitly highlights interest in molecular pathways that contribute to variation in aging rate, lifespan, and healthspan, suggesting projects could involve cross-species comparisons of conserved pathways, stress resistance mechanisms, metabolic or endocrine regulation, inflammation and immune function, genome maintenance, proteostasis, mitochondrial biology, or other physiological systems tied to aging outcomes. Because the mechanism is an R03, it is generally suited for discrete, hypothesis-driven studies, feasibility or pilot-style work, or narrowly defined projects that can generate early evidence, datasets, or proof-of-concept results to support larger future investigations.
From a funding and administrative standpoint, the opportunity was posted on July 20, 2012, with an original and current closing date of October 19, 2012, and an archive date of November 19, 2012, indicating the solicitation is historical and no longer open. The estimated total program funding listed is $500,000, and the award ceiling is $50,000, consistent with the small-grant nature of the R03 mechanism. There is no cost sharing or matching requirement, which lowers barriers for applicants by not requiring institutional or third-party funds to be committed as a condition of the award.
Eligibility is broad and includes a wide range of organizational types across the public, private, nonprofit, and educational sectors. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); state, county, city or township governments; special district governments; independent school districts; public housing authorities and Indian housing authorities; Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized); U.S. territories or possessions; and regional organizations. The FOA also allows participation by small businesses and for-profit organizations (including those other than small businesses). Additional explicitly named eligible applicant categories include Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, and eligible federal agencies, signaling an intent to support a diverse set of institutions and research environments.
The NIH is the sponsoring agency, and the program falls under the health funding activity category, reflecting its biomedical and translational relevance even though the work is fundamentally comparative and mechanistic. For reference and full details, the FOA points to the NIH Grants Guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-13-005.html). For access or technical issues related to the announcement, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is specifically for difficulties accessing the announcement or linking to it rather than for scientific or programmatic questions.
Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The opportunity is titled "Comparative Physiological Studies of Aging (R03)" and is identified as RFA-AG-13-005.
Which agency sponsors this program?
The sponsoring agency is the National Institutes of Health (NIH).
Is this grant opportunity still open?
No. The announcement is historical and no longer open. It was posted on July 20, 2012, had an original/current closing date of October 19, 2012, and an archive date of November 19, 2012.
What is the main goal of this FOA?
The central goal is to encourage small, targeted aging research projects that use comparative biology to explain why different vertebrate species age at different rates and show different patterns of lifespan and healthspan.
What does "comparative approaches" mean in this FOA?
It means the research is expected to leverage differences across vertebrate species, rather than studying aging in a single model species in isolation. The emphasis is on cross-species comparisons to uncover mechanisms linked to variation in aging outcomes.
What kinds of scientific questions is the FOA trying to address?
The FOA is aimed at understanding molecular pathways and physiological mechanisms that may drive slower aging, longer lifespan, or extended healthspan by comparing vertebrate species with different aging rates and life history patterns.
What research topics are explicitly highlighted as areas of interest?
The FOA highlights interest in molecular pathways that contribute to variation in aging rate, lifespan, and healthspan. Examples noted include stress resistance mechanisms, metabolic or endocrine regulation, inflammation and immune function, genome maintenance, proteostasis, mitochondrial biology, and other physiological systems tied to aging outcomes.
What grant mechanism is used, and what does that imply about project scope?
This opportunity uses the NIH R03 mechanism. It is generally suited for discrete, hypothesis-driven studies, feasibility or pilot-style work, or narrowly defined projects that can generate early evidence, datasets, or proof-of-concept results to support larger future investigations.
What is the CFDA number associated with this program?
The CFDA number listed is 93.866.
How much total funding was estimated for the program?
The estimated total program funding listed is $500,000.
What is the maximum award amount (award ceiling)?
The award ceiling is $50,000, consistent with the small-grant nature of an R03.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes many types of organizations across the public, private, nonprofit, and educational sectors, including higher education institutions (public/state-controlled and private), nonprofits (with or without 501(c)(3) status, other than institutions of higher education), and multiple government and community-based entity types.
Are state and local government entities eligible?
Yes. Eligible applicants include state governments and local governments such as county, city, or township governments, as well as special district governments.
Are school systems and housing authorities eligible?
Yes. The eligible categories listed include independent school districts, public housing authorities, and Indian housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. Eligible applicants include Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized).
Are U.S. territories or regional organizations eligible?
Yes. The FOA includes U.S. territories or possessions and regional organizations among eligible applicants.
Can for-profit organizations apply?
Yes. The FOA allows participation by small businesses and for-profit organizations (including those other than small businesses).
Does the FOA explicitly encourage applications from specific institution types?
It explicitly names additional eligible categories, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations.
Are federal agencies eligible to apply?
Yes. The FOA explicitly lists eligible federal agencies among the eligible applicant categories.
What funding activity category does this program fall under?
The program falls under the health funding activity category, reflecting biomedical and translational relevance even though the work is comparative and mechanistic.
Where can the full FOA text be found?
The FOA points to the NIH Grants Guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-13-005.html
Who should be contacted for trouble accessing the announcement or linking to it?
For access or technical issues (such as difficulty accessing the announcement or linking to it), the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Is the listed contact intended for scientific or programmatic questions?
No. The provided contact is specifically for difficulties accessing the announcement or linking to it, not for scientific or programmatic questions.
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