Opportunity Information: Apply for CDC RFA GH12 1257SUPP16

  • The HHS-CDC in the health sector is offering a public funding opportunity titled "Comprehensive Facility-Based Technical Assistance in the Context of Health Systems Strengthening in South Africa under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Jan 09, 2016 and posted on Jan 09, 2016.
  • Applicants must submit their applications by Mar 08, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA GH12 1257SUPP16

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Opportunity Summary:

The grant opportunity titled "Comprehensive Facility-Based Technical Assistance in the Context of Health Systems Strengthening in South Africa under PEPFAR" (Funding Opportunity Number CDC RFA GH12 1257SUPP16) is a discretionary funding announcement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (HHS-CDC). It is structured as a cooperative agreement, which typically means the funder expects to remain actively involved in the program’s direction, oversight, and coordination as the work is implemented. The award was designed as a single expected award, with an application deadline of March 8, 2016. The CFDA listing attached to the opportunity is 93.067, aligning it with CDC global health programming under PEPFAR.

The core purpose of the funding is to support implementation of the DREAMS initiative, a large multi-partner effort launched in 2015 through a $210 million partnership involving PEPFAR, the Bill and Melinda Gates Foundation, and the Nike Foundation. DREAMS stands for Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe, and it is focused on dramatically reducing new HIV infections among adolescent girls and young women (AGYW) in ten sub-Saharan African countries, including South Africa. In this announcement, the eligible applicant named in the description is the Aurum Health Institute, and eligibility is further referenced under an "Others" category with additional clarification expected in the full eligibility text.

Programmatically, DREAMS is framed as a combination prevention approach that deliberately goes beyond clinic-based services alone. The initiative emphasizes layering multiple evidence-based interventions that address both immediate HIV risk and the broader structural factors that shape vulnerability for girls and young women. These structural drivers are spelled out in the opportunity description and include poverty, gender inequality, sexual violence, and lack of access to education. The logic is that biomedical and clinical interventions are necessary but not sufficient if the social and economic conditions that increase risk remain unchanged, so DREAMS is designed to integrate health services with community, family, and social protection strategies.

Geographically, the DREAMS funding described here targets five priority districts in South Africa, selected for high burden and high transmission dynamics. Three are in KwaZulu-Natal: eThekwini, uMgungundlovu, and uMkhanyakude. Two are in Gauteng: the City of Johannesburg and Ekurhuleni. Across these five districts there are 31 sub-districts, and DREAMS is intended to concentrate resources in 19 sub-districts identified as particularly high burden and high transmission. This reflects a targeted, data-driven deployment model where investments are focused where they are expected to have the greatest impact on incidence among AGYW.

The opportunity describes four main objective areas that guide DREAMS implementation. First is empowering girls and young women, which generally implies building knowledge, skills, agency, and access to services so that AGYW can better protect their health and exercise control over key life decisions. Second is mobilizing communities, pointing to the need for community-level norms change, local leadership engagement, and supportive environments that reduce stigma and tolerance for violence while increasing demand for prevention and supportive services. Third is strengthening families, recognizing the role of households and caregivers in protection, schooling, stability, and reducing exposure to exploitation or unsafe partnerships. Fourth is providing social protection, which commonly refers to measures that reduce economic vulnerability and keep girls connected to education and support systems, thereby lowering the likelihood of transactional sex, early school dropout, and other pathways associated with increased HIV risk.

In terms of results, the FOA explicitly links its support to ambitious incidence reduction targets among 15 to 24 year old adolescent girls and young women. The stated goals are to reduce new HIV infections in this age group by 25 percent by the end of 2016 and by 40 percent by the end of 2017. Beyond incidence outcomes, the announcement also ties DREAMS to broader well-being and developmental outcomes that are closely related to HIV risk, including increased secondary school enrollment, attendance, and completion, along with reductions in violence and unintended pregnancy. Taken together, the grant opportunity is positioned as a health systems strengthening and technical assistance effort under PEPFAR that operationalizes DREAMS in priority districts, using a multi-sector package to change both service access and the underlying conditions that drive HIV vulnerability among adolescent girls and young women.

Frequently Asked Questions (FAQs)

What is the full title of this grant opportunity?

The opportunity is titled "Comprehensive Facility-Based Technical Assistance in the Context of Health Systems Strengthening in South Africa under PEPFAR."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is CDC RFA GH12 1257SUPP16.

Which U.S. agency is offering this funding?

This is a discretionary funding announcement from the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC).

What type of award is this (grant vs. cooperative agreement)?

This opportunity is structured as a cooperative agreement. That typically means the funder expects to remain actively involved in the program's direction, oversight, and coordination during implementation.

How many awards were expected under this announcement?

The award was designed as a single expected award.

What was the application deadline?

The application deadline listed for this opportunity was March 8, 2016.

What CFDA number is associated with this opportunity?

The CFDA listing attached to the opportunity is 93.067, aligning it with CDC global health programming under PEPFAR.

What is the main purpose of the funding?

The core purpose is to support implementation of the DREAMS initiative in South Africa as part of PEPFAR-related programming, with a focus on reducing new HIV infections among adolescent girls and young women (AGYW) through a combination prevention approach.

What does DREAMS stand for?

DREAMS stands for Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe.

When was the DREAMS initiative launched and what is its overall scale?

DREAMS was launched in 2015 as a $210 million partnership involving PEPFAR, the Bill and Melinda Gates Foundation, and the Nike Foundation.

Who is DREAMS designed to benefit?

DREAMS is focused on dramatically reducing new HIV infections among adolescent girls and young women (AGYW), specifically referenced in this announcement as ages 15 to 24.

In how many countries does DREAMS operate, and is South Africa included?

DREAMS targets ten sub-Saharan African countries, and South Africa is explicitly included.

What approach does DREAMS use to reduce HIV infections?

DREAMS is described as a combination prevention approach that goes beyond clinic-based services alone. It emphasizes layering multiple evidence-based interventions to address both immediate HIV risk and the broader structural drivers of vulnerability.

What structural drivers of HIV vulnerability are specifically named in the opportunity description?

The opportunity description identifies poverty, gender inequality, sexual violence, and lack of access to education as key structural drivers that increase vulnerability for girls and young women.

Why does the program emphasize more than biomedical or clinic-based services?

The description explains that biomedical and clinical interventions are necessary but not sufficient if the social and economic conditions that increase HIV risk remain unchanged. DREAMS is therefore designed to integrate health services with community, family, and social protection strategies.

Where in South Africa is the DREAMS funding targeted under this announcement?

The described funding targets five priority districts in South Africa selected for high burden and high transmission dynamics: eThekwini, uMgungundlovu, and uMkhanyakude (KwaZulu-Natal), and the City of Johannesburg and Ekurhuleni (Gauteng).

How many sub-districts are included across the targeted districts, and how many are prioritized for concentrated investment?

Across the five districts there are 31 sub-districts. DREAMS is intended to concentrate resources in 19 sub-districts identified as particularly high burden and high transmission.

How are resources intended to be allocated across locations?

The description reflects a targeted, data-driven deployment model, with investments focused in sub-districts where they are expected to have the greatest impact on HIV incidence among AGYW.

What are the four main objective areas that guide DREAMS implementation in this opportunity?

The opportunity describes four main objective areas: (1) empowering girls and young women, (2) mobilizing communities, (3) strengthening families, and (4) providing social protection.

What does "empowering girls and young women" mean in this context?

Within the description, empowering AGYW generally implies building knowledge, skills, agency, and access to services so that girls and young women can better protect their health and exercise control over key life decisions.

What does "mobilizing communities" refer to in the opportunity description?

Mobilizing communities points to community-level norms change, engagement of local leadership, and building supportive environments that reduce stigma and tolerance for violence while increasing demand for prevention and supportive services.

What does "strengthening families" mean in DREAMS as described here?

Strengthening families recognizes the role of households and caregivers in protection, schooling, stability, and reducing exposure to exploitation or unsafe partnerships.

What does "social protection" mean in this opportunity?

Social protection commonly refers to measures that reduce economic vulnerability and keep girls connected to education and support systems, thereby lowering the likelihood of transactional sex, early school dropout, and other pathways associated with increased HIV risk.

What HIV incidence reduction targets are explicitly stated?

The FOA states goals to reduce new HIV infections among 15 to 24 year old AGYW by 25 percent by the end of 2016 and by 40 percent by the end of 2017.

Are there outcomes beyond HIV incidence mentioned in the announcement?

Yes. The announcement ties DREAMS to broader well-being and developmental outcomes related to HIV risk, including increased secondary school enrollment, attendance, and completion, along with reductions in violence and unintended pregnancy.

How is this opportunity positioned within PEPFAR programming?

It is positioned as a health systems strengthening and technical assistance effort under PEPFAR that operationalizes DREAMS in priority districts through a multi-sector package addressing both service access and underlying drivers of HIV vulnerability.

Who is identified as the eligible applicant in the description provided?

The eligible applicant named in the description is the Aurum Health Institute.

Does the opportunity mention any other eligibility category?

Yes. Eligibility is also referenced under an "Others" category, with additional clarification expected in the full eligibility text.

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