Opportunity Information: Apply for RFA CA 09 501

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Comprehensive Minority Institution/Cancer Center Partnership (Limited Competition U54)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.397 Cancer Centers Support Grants 93.398 Cancer Research Manpower 93.399 Cancer Control.
  • This funding opportunity was created on Jan 2, 2009 and posted on Jan 2, 2009.
  • Applicants must submit their applications by Mar 17, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession NCI designated Cancer Centers (or group of centers) Minority serving institutions Only institutions that are current MI/CCP U54 awardees or U56 awardees under cooperative planning grant for MI/CCP are eligible to compete for awards under this limited competition FOA. Applications will only be accepted from MSIs, as defined in the Purpose section (e.g., Historically Black Colleges and Universities HBCUs, Hispanic Serving Institutions HSIs and Tribal Institutions e.g., Colleges) either in the United States or in territories under U.S. jurisdiction, and from institutions that are NCI designated Cancer Centers (or groups of centers) that wish to develop comprehensive partnerships. Each partnership must include both types of institutions. Three or more institutions (e.g. triads, groups of Cancer Centers) may apply in response to this announcement only when approved by the NCI prior to submission. MSIs with medical schools, MSIs with more focused education and research programs (e.g., Masters and Ph.D. programs), as well as MSIs that offer only baccalaureate degrees and Tribal Colleges may all participate in this initiative.
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Opportunity Summary:

The Comprehensive Minority Institution/Cancer Center Partnership (Limited Competition U54) grant opportunity (RFA-CA-09-501) is a National Cancer Institute (NCI) cooperative agreement designed to support full implementation of strong, long-term partnerships between Minority Serving Institutions (MSIs) and NCI-designated Cancer Centers (or, with prior approval, groups of centers and/or multi-institution partnerships). The core aim is to build deeper, more intensive collaborations that strengthen national cancer research and training capacity focused on understanding and reducing cancer disparities that disproportionately affect racial and ethnic minority communities and socioeconomically disadvantaged populations. Unlike a standard research grant, the U54 cooperative agreement structure signals that NCI expects substantial programmatic involvement and coordination with awardees as these partnerships are carried out.

This is a limited competition announcement, meaning it is not open to entirely new partnerships starting from scratch. Eligibility is restricted to institutions already involved in this MI/CCP initiative: only current MI/CCP U54 awardees seeking continued support, and U56 cooperative planning grant awardees seeking to transition from a planning/development phase into full MI/CCP status, may apply. In every application, the partnership must include both an MSI (as defined by the program) and an NCI-designated Cancer Center (or approved group of centers). The FOA explicitly recognizes that MSIs come in different forms and capacities, so eligible MSIs may include those with medical schools, those primarily offering Masters and PhD training and research programs, and those focused on baccalaureate education, including Tribal Colleges.

The applicant pool is broad within that limited-competition boundary. MSIs referenced include Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions (HSIs), Alaska Native and Native Hawaiian Serving Institutions, and Tribal institutions such as Tribally Controlled Colleges and Universities (TCCUs). The eligibility listing also includes public and state-controlled institutions of higher education, private institutions of higher education, U.S. territories or possessions, and certain tribal entities and regional organizations, as applicable. However, the defining gatekeeper requirement remains that the institutions must already be current U54 or U56 MI/CCP awardees, and the application must be submitted by/for an MSI in formal partnership with an NCI-designated Cancer Center.

Programmatically, the FOA centers on developing comprehensive, integrated cancer programs through partnership. The intent is to leverage the strengths of Cancer Centers (infrastructure, clinical and translational research capacity, established research programs) alongside the unique strengths and community connections of MSIs (access to underserved populations, culturally informed approaches, and pipelines for minority scientists and clinicians). The collaborations are meant to go beyond isolated projects and instead create an organized platform for sustained work on cancer disparities, spanning research, education, and potentially broader cancer control and community-oriented efforts aligned with NCI priorities.

From an administrative standpoint, the opportunity is categorized as discretionary funding and uses the cooperative agreement funding instrument. It falls under NIH/NCI health and education-related activity categories and maps to multiple CFDA cancer research and support areas (including prevention, detection/diagnosis, treatment, biology, cancer centers support, research manpower, and cancer control). The announcement states there is no cost-sharing or matching requirement. The opportunity was posted January 2, 2009, with an application closing date of March 17, 2009, an estimated total funding level of $5,000,000, and an archive date of April 17, 2009. The full funding announcement was made available through the NIH Grants Guide, and the NIH Office of Extramural Research (OER) webmaster contact is provided for access or linking issues.

FAQs: Comprehensive Minority Institution/Cancer Center Partnership (Limited Competition U54) - RFA-CA-09-501

What is the Comprehensive Minority Institution/Cancer Center Partnership (MI/CCP) U54 opportunity?

It is a National Cancer Institute (NCI) cooperative agreement (U54) designed to support full implementation of strong, long-term partnerships between Minority Serving Institutions (MSIs) and NCI-designated Cancer Centers. The program focuses on building deeper, more intensive collaborations that strengthen cancer research and training capacity aimed at understanding and reducing cancer disparities.

What is the funding opportunity announcement (FOA) number for this grant?

The FOA is RFA-CA-09-501.

Which NIH institute is sponsoring this opportunity?

The opportunity is sponsored by the National Cancer Institute (NCI).

What does it mean that this is a cooperative agreement (U54) rather than a standard research grant?

The U54 cooperative agreement structure indicates that NCI expects substantial programmatic involvement and coordination with awardees during the implementation of the partnership activities, rather than operating as a more independent investigator-initiated research grant.

Is this a limited competition funding opportunity?

Yes. This is a limited competition announcement and is not open to entirely new partnerships starting from scratch.

Who is eligible to apply under this limited competition?

Eligibility is restricted to institutions already involved in the MI/CCP initiative: (1) current MI/CCP U54 awardees seeking continued support, and (2) U56 cooperative planning grant awardees seeking to transition from the planning/development phase into full MI/CCP status.

Can brand-new MSI/Cancer Center partnerships apply if they have never held a MI/CCP award?

No. The FOA states this limited competition is not open to entirely new partnerships starting from scratch. Applicants must already be current MI/CCP U54 awardees or U56 planning grant awardees under the MI/CCP initiative.

What partnerships are required in every application?

Every application must include a formal partnership between an MSI (as defined by the program) and an NCI-designated Cancer Center. With prior approval, the Cancer Center partner may be a group of centers and/or a multi-institution partnership.

Can a group of Cancer Centers or a multi-institution partnership serve as the Cancer Center partner?

Yes, but only with prior approval, according to the FOA.

What types of Minority Serving Institutions (MSIs) are recognized as eligible partners?

The FOA recognizes that MSIs vary in form and capacity. Eligible MSIs may include institutions with medical schools, institutions primarily offering Masters and PhD training and research programs, and institutions focused on baccalaureate education, including Tribal Colleges.

Which MSI categories are specifically referenced in the announcement?

The FOA references MSIs such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions (HSIs), Alaska Native and Native Hawaiian Serving Institutions, and Tribal institutions including Tribally Controlled Colleges and Universities (TCCUs).

Does the eligibility list include different types of higher education institutions and entities?

Yes. The eligibility listing includes public and state-controlled institutions of higher education, private institutions of higher education, U.S. territories or possessions, and certain tribal entities and regional organizations, as applicable. However, the key eligibility requirement remains prior participation as a current U54 or U56 MI/CCP awardee, and the presence of an MSI-Cancer Center partnership.

What is the main goal of the MI/CCP U54 program?

The core aim is to develop comprehensive, integrated cancer programs through MSI and Cancer Center partnerships, strengthening national cancer research and training capacity with a focus on understanding and reducing cancer disparities that disproportionately affect racial and ethnic minority communities and socioeconomically disadvantaged populations.

What is meant by building a "comprehensive, integrated cancer program" through partnership?

Based on the FOA description, the intent is to move beyond isolated or stand-alone projects and instead create an organized platform for sustained collaboration. The partnership is meant to support coordinated work spanning research and education, and potentially broader cancer control and community-oriented efforts aligned with NCI priorities.

How are the strengths of Cancer Centers and MSIs expected to complement each other in this program?

The FOA describes leveraging Cancer Center strengths such as infrastructure, clinical and translational research capacity, and established research programs, alongside MSI strengths such as community connections, access to underserved populations, culturally informed approaches, and pipelines for minority scientists and clinicians.

What populations is this program intended to benefit?

The program is focused on cancer disparities that disproportionately affect racial and ethnic minority communities and socioeconomically disadvantaged populations.

What type of funding category is this opportunity?

The opportunity is categorized as discretionary funding.

Is there a cost-sharing or matching requirement?

No. The announcement states there is no cost-sharing or matching requirement.

What activity categories does this opportunity fall under?

It falls under NIH/NCI health and education-related activity categories.

What cancer-related program areas does the FOA map to?

The FOA maps to multiple CFDA cancer research and support areas, including prevention, detection/diagnosis, treatment, biology, cancer centers support, research manpower, and cancer control.

When was this opportunity posted, and what were the key dates?

The opportunity was posted on January 2, 2009. The application closing date was March 17, 2009. The archive date was April 17, 2009.

What was the estimated total funding level for this FOA?

The FOA listed an estimated total funding level of $5,000,000.

Where was the full funding announcement made available?

The full funding announcement was made available through the NIH Grants Guide.

Who is listed as the contact for access or linking issues related to the announcement?

The NIH Office of Extramural Research (OER) webmaster contact is provided for access or linking issues.

What is the overarching intent of NCI involvement in this cooperative agreement?

The FOA indicates that NCI expects substantial programmatic involvement and coordination with awardees as the partnerships are carried out, consistent with the cooperative agreement mechanism.

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