Opportunity Information: Apply for PAR 15 103
Apply for PAR 15 103
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.397 Cancer Centers Support Grants 93.398 Cancer Research Manpower 93.399 Cancer Control.
- This funding opportunity was created on Jan 29, 2015 and posted on Jan 29, 2015.
- Applicants must submit their applications by Jan 28, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) State governments City or township governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Special district governments County governments Private institutions of higher education Small businesses For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54) grant opportunity (PAR-15-103) is a National Institutes of Health (NIH), National Cancer Institute (NCI) cooperative agreement designed to strengthen long-term, high-impact collaborations focused on reducing cancer health disparities. It funds "Comprehensive Partnerships" between NCI-designated Cancer Centers and institutions that serve underserved health disparity populations and educate underrepresented students, referred to in the announcement as ISUPS. The central idea is to build and sustain deep, integrated collaborations that can generate stronger cancer research and training programs, with an emphasis on understanding why major cancer disparities exist across different populations and how those disparities affect outcomes.
This is a limited competition FOA using the U54 mechanism, which means it supports complex, multi-component partnership programs and involves substantial NIH/NCI programmatic involvement compared to a standard research grant. The cooperative agreement structure typically indicates that NCI staff will play an active role in coordinating, guiding, or otherwise participating in the funded program to help ensure the partnership meets CPACHE goals and maintains accountability to the overall cancer health equity mission.
The FOA is specifically intended for two main groups. First, it supports partnerships that are already comprehensive under the U54 mechanism (including those that may be inactive at the time of application but were formerly supported as U54 comprehensive partnerships). Second, it is meant to elevate strong developing partnerships, such as those supported under the U56 mechanism or other similar arrangements, into full "comprehensive" status. In practice, this signals an emphasis on continuity, maturation, and scaling of proven collaborations rather than starting entirely new, untested relationships from scratch.
Programmatically, CPACHE is framed around building stronger national cancer programs that are capable of rigorously investigating the drivers of cancer disparities. That includes studying the underlying reasons certain communities experience higher cancer incidence, later-stage diagnosis, worse survival, or disproportionate burdens from cancer risk factors and care barriers. The partnership model is intended to combine the research infrastructure, specialized expertise, and resources of NCI-designated Cancer Centers with the community reach, student pipelines, and lived experience connections often held by ISUPS institutions. The expected result is not only better science, but also stronger capacity and workforce development aligned with cancer health equity.
Eligibility is broad across many domestic U.S. organization types (for example, state and local governments, public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses, and certain for-profit entities). The FOA also explicitly calls out a range of mission-aligned institution types and organizations as eligible applicants, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based and community-based organizations and U.S. territories or possessions. Foreign institutions and foreign components are not allowed, and non-U.S. entities are not eligible to apply, reflecting the program's domestic focus on U.S. cancer disparities and workforce development.
From an administrative standpoint, this opportunity is categorized as discretionary funding and falls under education and health activity areas, with CFDA program listings spanning core cancer research domains (prevention, detection/diagnosis, treatment, biology), cancer center support, cancer control, and research manpower. There is no cost-sharing or matching requirement listed. The FOA was posted January 29, 2015, with an original and final closing date of January 28, 2017, and it was archived February 28, 2017, meaning it is not currently open but remains a useful reference point for understanding CPACHE program design and requirements at that time.
Overall, CPACHE (U54) is best understood as a structured, NCI-involved partnership platform aimed at producing sustained institutional collaboration, stronger research and training capacity, and actionable insights into the causes and consequences of cancer inequities, particularly for underserved populations and in settings that educate and support underrepresented students entering the cancer research and healthcare pipeline.
Frequently Asked Questions (FAQs): Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54) - PAR-15-103
What is the CPACHE (U54) funding opportunity?
CPACHE (U54) is a National Institutes of Health (NIH), National Cancer Institute (NCI) cooperative agreement funding opportunity (PAR-15-103) intended to strengthen long-term, high-impact collaborations focused on reducing cancer health disparities through sustained partnership programs.
What does CPACHE stand for?
CPACHE stands for Comprehensive Partnerships to Advance Cancer Health Equity.
Which NIH institute runs CPACHE?
The program is run by the National Cancer Institute (NCI), which is part of the National Institutes of Health (NIH).
What is the main goal of CPACHE?
The main goal is to build and sustain deep, integrated collaborations that strengthen cancer research and training capacity and produce actionable understanding of why major cancer disparities exist across populations and how those disparities affect outcomes.
What types of disparities is CPACHE focused on?
Based on the announcement description, CPACHE is focused on cancer health disparities such as higher cancer incidence, later-stage diagnosis, worse survival, and disproportionate burdens related to cancer risk factors and barriers to care in underserved populations.
What is a "Comprehensive Partnership" in CPACHE?
A Comprehensive Partnership refers to a structured, multi-component collaboration between an NCI-designated Cancer Center and an institution that serves underserved health disparity populations and educates underrepresented students (referred to as an ISUPS in the announcement). The partnership is intended to be long-term, integrated, and capable of producing stronger research and training programs focused on cancer health equity.
Who are the typical partners in a CPACHE U54 application?
The opportunity funds partnerships between NCI-designated Cancer Centers and institutions serving underserved health disparity populations and educating underrepresented students (ISUPS). The model emphasizes combining the Cancer Center's research infrastructure and expertise with the ISUPS institution's community reach and student pipeline.
What does ISUPS mean in this announcement?
ISUPS refers to institutions that serve underserved health disparity populations and educate underrepresented students, as described in the opportunity summary.
What grant mechanism is used for CPACHE?
CPACHE uses the U54 mechanism, which supports complex, multi-component partnership programs.
What does it mean that CPACHE is a cooperative agreement?
As a cooperative agreement, CPACHE involves substantial NIH/NCI programmatic involvement compared to a standard research grant. This typically indicates that NCI staff will play an active role in coordinating, guiding, or participating in the funded program to support CPACHE goals and accountability to the cancer health equity mission.
Is CPACHE (U54) a limited competition funding opportunity?
Yes. The opportunity is described as a limited competition FOA using the U54 mechanism.
Is CPACHE intended for brand-new partnerships?
The description emphasizes continuity and maturation of proven collaborations rather than starting entirely new, untested relationships. It is intended for (1) partnerships already comprehensive under the U54 mechanism (including those formerly supported as U54 comprehensive partnerships, even if inactive at application time) and (2) strong developing partnerships (such as those supported under the U56 mechanism or similar arrangements) that are ready to be elevated into full comprehensive status.
How does CPACHE relate to the U56 mechanism?
CPACHE (U54) is intended, in part, to elevate strong developing partnerships (including those supported under U56 or similar arrangements) into full "comprehensive" partnerships under the U54 mechanism.
What kinds of activities or outcomes does CPACHE aim to support?
CPACHE is framed around building stronger national cancer programs capable of rigorously investigating the drivers of cancer disparities, strengthening research and training programs, and building capacity and workforce development aligned with cancer health equity.
How does CPACHE strengthen workforce development?
The partnership model is described as leveraging ISUPS institutions' student pipelines and connections to underrepresented students, combined with Cancer Center research infrastructure and expertise, to strengthen training capacity and workforce development aligned with cancer health equity.
What types of organizations are eligible to apply?
Eligibility is described as broad across many domestic U.S. organization types, including (as examples) state and local governments, public and private institutions of higher education, nonprofits with or without 501(c)(3) status, small businesses, and certain for-profit entities.
Are minority-serving institutions explicitly included as eligible applicants?
Yes. The opportunity explicitly calls out mission-aligned institutions and organizations as eligible applicants, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based and community-based organizations eligible?
Yes. Faith-based and community-based organizations are explicitly mentioned among eligible applicant types.
Are U.S. territories or possessions included in eligibility?
Yes. U.S. territories or possessions are explicitly mentioned as eligible.
Are foreign institutions or foreign components allowed?
No. Foreign institutions and foreign components are not allowed, and non-U.S. entities are not eligible to apply.
What are the activity areas for this funding opportunity?
The opportunity is categorized under education and health activity areas.
Is this considered discretionary funding?
Yes. The opportunity is categorized as discretionary funding.
Are there cost-sharing or matching requirements?
No cost-sharing or matching requirement is listed in the provided description.
What cancer research domains are associated with the CFDA listings mentioned?
The CFDA program listings span core cancer research domains including prevention, detection/diagnosis, treatment, biology, cancer center support, cancer control, and research manpower.
When was PAR-15-103 posted?
The FOA was posted on January 29, 2015.
What was the closing date for applications?
The original and final closing date listed is January 28, 2017.
Is this opportunity currently open?
No. The FOA was archived on February 28, 2017, and is not currently open.
Why might PAR-15-103 still be useful if it is archived?
Even though it is not open, it can still be a useful reference point for understanding CPACHE program design and requirements as they were described at that time, including the partnership model, cooperative agreement expectations, and the emphasis on cancer health equity.
What is the core partnership strategy described by CPACHE?
The core strategy is to combine the research infrastructure, specialized expertise, and resources of NCI-designated Cancer Centers with the community reach, lived-experience connections, and underrepresented student pipelines often held by ISUPS institutions, with the intent to produce stronger science and sustainable capacity for cancer health equity work.
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| Administrative Supplements to Promote Cancer Prevention and Control Research in Low and Middle Income Countries (Admin Supp) Apply for PAR 15 155 Funding Number: PAR 15 155 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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