Continuing Enhanced National Surveillance for Prion Diseases in the United States | Apply Online

Opportunity Summary:

This funding opportunity, titled "Continuing Enhanced National Surveillance for Prion Diseases in the United States," is a CDC continuation cooperative agreement focused on sustaining and strengthening national surveillance activities for prion diseases across the United States. Prion diseases are rare, fatal neurodegenerative conditions (such as Creutzfeldt-Jakob disease and related disorders) that require specialized public health monitoring because they can be difficult to diagnose, have significant clinical and epidemiologic implications, and in certain circumstances raise concerns about healthcare-associated transmission or emerging variants. The central purpose of the opportunity is to maintain an enhanced surveillance system that can reliably identify cases, track trends over time, improve timeliness and completeness of reporting, and support the broader public health infrastructure needed to detect unusual patterns, potential outbreaks, or novel presentations.

Administratively, the announcement is issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (HHS-CDC), specifically under NCEZID (National Center for Emerging and Zoonotic Infectious Diseases), with the program tied to CFDA 93.283. It is explicitly categorized as a "Continuation" opportunity, meaning it is intended to continue support for existing work rather than initiate an entirely new competitive program. The funding instrument is a cooperative agreement, which generally indicates an ongoing, substantial level of involvement by CDC in the supported activities compared to a standard grant. In practice, that cooperative structure typically aligns the recipient's work with CDC technical guidance, shared protocols, national standards for surveillance, and coordinated reporting or data-sharing expectations to ensure consistent national coverage and quality.

The opportunity number is CDC-RFA-CK12-120805CONT16. The posting date and creation date are both April 26, 2016, and the closing date is May 26, 2016. The activity category is listed as "Health," reflecting the public health surveillance and epidemiology focus. Eligibility is listed as "Others," with the announcement directing readers to an additional eligibility clarification field (not included in the excerpt), which commonly means the continuation is limited to specific previously funded entities, designated partners, or organizations meeting particular criteria set by the CDC for this surveillance function.

In terms of scale, the announcement lists an expected 50 awards. The award ceiling is shown as 0, which usually signals that a specific maximum per award is not stated in the basic summary table, may be provided in the full announcement narrative, or may vary by recipient based on continuation funding levels, approved scopes of work, or available appropriations. Because this is a continuation mechanism and involves enhanced national surveillance, the supported work would typically revolve around core surveillance operations such as case ascertainment, investigation support, coordination with state and local health departments, clinical and laboratory partners, and standardized collection and analysis of epidemiologic and clinical information. It may also include efforts to improve diagnostic awareness, facilitate access to specialized testing and expert consultation pathways, and ensure consistent classification of cases for national reporting and trend analysis.

Overall, the grant opportunity is best understood as the CDC maintaining a coordinated, enhanced national system for monitoring prion diseases, using a cooperative agreement model to keep surveillance methods consistent and responsive to public health needs. The continuation framing, the CDC program placement, and the surveillance-specific title all point to sustaining established national capacity rather than building an entirely new program from scratch.

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