Cooperative Agreement with the South Africa National Health Laboratory Service (NHLS) | Apply Online

Opportunity Summary:

This funding opportunity (CDC RFA GH11-1199) is a discretionary cooperative agreement issued by the Centers for Disease Control and Prevention under CFDA 93.283 (CDC Investigations and Technical Assistance). It was designed as a single-award agreement, with an estimated total funding level of $15,000,000. The funding instrument is a cooperative agreement, which typically signals substantial involvement by the CDC in programmatic direction, technical support, and oversight compared with a standard grant. No cost sharing or matching was required. The notice was posted March 10, 2011, created April 22, 2011, and ultimately closed May 31, 2011 at 5:00 pm U.S. Eastern time (originally scheduled to close May 9, 2011). The opportunity was later archived June 30, 2011. While an award ceiling and floor are listed as $0, this generally reflects a posting or formatting convention in older listings rather than an absence of funding, especially given the stated total of $15 million.

Eligibility was restricted to one entity: the South Africa National Health Laboratory Service (NHLS). The announcement explicitly states that assistance would be provided only to NHLS and that no other applications were solicited, describing NHLS as the most appropriate and qualified organization to carry out the activities. In practical terms, this makes the announcement a targeted, sole-eligible recipient cooperative agreement intended to formalize CDC support for a specific national laboratory and public health partner in South Africa rather than a competitive open solicitation.

The core purpose of the cooperative agreement was broad public health systems strengthening and disease control work at a national level in South Africa, centered on three linked functions: (1) conducting public health surveillance and epidemiologic assessments to understand and track conditions driving disease, premature death, and reduced quality of life; (2) developing and improving high-quality laboratory systems and diagnostic capacity; and (3) implementing evidence-based public health programs informed by surveillance and laboratory findings. The scope is intentionally wide, reflecting the central role laboratories play in detection, confirmation, monitoring, and response across many health threats, and positioning NHLS as a backbone institution for national surveillance and response.

Within that broad scope, the announcement highlights infectious diseases as a major emphasis, with particular attention to HIV/AIDS. The HIV/AIDS focus is described in practical, risk-reduction terms and explicitly includes blood safety, injection safety, infection control, and medical waste management, which are critical areas where strong laboratory practice, quality systems, and facility-level standards directly reduce transmission risk and improve patient and healthcare worker safety. Beyond HIV/AIDS, the agreement also encompasses malaria; emerging and re-emerging infectious diseases; zoonotic diseases; neglected tropical diseases; tuberculosis; and influenza and other diseases with pandemic potential. The inclusion of influenza and other pandemic-potential diseases, alongside emergency preparedness and response, signals an intent to bolster early detection and surge capacity, as well as coordinated response mechanisms that rely heavily on laboratory readiness, specimen referral networks, and timely reporting.

The opportunity also extends beyond infectious disease to include environmental health issues, chronic diseases, maternal and child health, reproductive health, injury control and prevention, public health preparedness, and biosafety. This mix suggests a comprehensive public health laboratory and surveillance agenda, where NHLS capacity is expected to support not only outbreak-oriented work but also ongoing population health monitoring and program evaluation. Biosafety is specifically called out, reinforcing the expectation that laboratory expansion and increased diagnostic throughput must be paired with safe handling of pathogens, proper containment practices, and workforce training to protect staff and communities while maintaining confidence in public health operations.

Operationally, the cooperative agreement can be understood as CDC partnering with NHLS to strengthen national surveillance and epidemiology, upgrade laboratory quality and diagnostic services, and translate evidence into public health action across a wide range of priority conditions. The announcement provides a contact point at CDCs Procurement and Grants Office for technical access issues, indicating that full details were provided in the full announcement package (the additional information link noted in the synopsis is inactive in the excerpt).

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