Opportunity Information: Apply for G16AS00087

  • The DOI-USGS1 in the science and technology and other research and development sector is offering a public funding opportunity titled "Cooperative Ecosystem Studies Unit, Chesapeake Watershed CESU" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 15.808.
  • This funding opportunity was created on Jun 13, 2016 and posted on Jun 13, 2016.
  • Applicants must submit their applications by Jul 01, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $47,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for G16AS00087

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Opportunity Summary:

The Cooperative Ecosystem Studies Unit, Chesapeake Watershed CESU funding opportunity (Funding Opportunity Number G16AS00087) was issued by the U.S. Geological Survey (USGS) under the Department of the Interior, specifically through the Patuxent Wildlife Research Center. It is a discretionary science and technology research award offered as a cooperative agreement, meaning the project is expected to involve substantial collaboration or involvement from the federal scientific staff during the course of the work rather than being a simple pass-through grant. The opportunity was posted on June 13, 2016, with an application closing date of July 1, 2016.

The purpose of the award is to support a focused research effort titled "Development and Application of Wild Duck-Specific Peptide Arrays for Kinome Analysis of Influenza Immuno-metabolism." In practical terms, the project is aimed at building and using a duck-specific peptide microarray tool that can measure phosphorylation-driven signaling activity (kinome responses) in wild ducks within the genus Anas. Phosphorylation is one of the core molecular switches cells use to control immune and metabolic pathways, so a kinome-focused approach can reveal how a host responds at the signaling level when exposed to infection or other immune challenges.

The main research objectives are twofold. First, the recipient is expected to design and produce a peptide array tailored to Anas species that can capture immune and metabolic signaling signatures by detecting phosphorylation-based changes across relevant pathways. Second, the project will apply that newly developed tool to characterize cellular signal transduction responses when duck cells are challenged with avian influenza, helping define how infection influences immuno-metabolism and host defense signaling. This kind of work supports a better mechanistic understanding of avian influenza interactions with wild waterfowl, which are important natural hosts and reservoirs for influenza viruses, and can inform surveillance or management strategies by clarifying host response biology.

The anticipated funding level is modest and targeted: a single expected award with a maximum (award ceiling) of $47,000. The CFDA number associated with the opportunity is 15.808. Eligibility is listed broadly as "Others," with additional clarification referenced in the full announcement under an eligibility information section, which typically indicates that only certain organizations (often CESU network partners such as universities, nonprofits, or other research institutions aligned with the CESU agreement) may apply or may be preferred. Overall, this opportunity is a small, specialized research award intended to produce a practical immunological tool (a duck-specific kinome peptide array) and generate proof-of-concept or early-stage biological findings on signaling responses to avian influenza in wild ducks.

Frequently Asked Questions (FAQs)

What is the name of this funding opportunity?

The funding opportunity is the Cooperative Ecosystem Studies Unit, Chesapeake Watershed CESU funding opportunity.

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is G16AS00087.

Which federal agency is offering this award?

The award was issued by the U.S. Geological Survey (USGS).

Which Department is USGS operating under for this opportunity?

USGS issued the opportunity under the Department of the Interior.

Which USGS center is specifically tied to this opportunity?

The opportunity is issued through the Patuxent Wildlife Research Center.

What type of award is being offered (grant vs. cooperative agreement)?

This is offered as a cooperative agreement.

What does it mean that this is a cooperative agreement?

It means the project is expected to involve substantial collaboration or involvement from federal scientific staff during the course of the work, rather than being a simple pass-through grant.

Is this a discretionary award?

Yes. It is described as a discretionary science and technology research award.

When was the opportunity posted?

The opportunity was posted on June 13, 2016.

What is the application closing date?

The application closing date was July 1, 2016.

What is the purpose of this award?

The purpose is to support a focused research effort titled "Development and Application of Wild Duck-Specific Peptide Arrays for Kinome Analysis of Influenza Immuno-metabolism."

What project or research topic is being funded?

The funded work focuses on developing and applying wild duck-specific peptide arrays to analyze kinome (phosphorylation-driven signaling) responses related to influenza immuno-metabolism.

What is the practical deliverable the project is aiming to produce?

A key deliverable is a duck-specific peptide microarray tool designed to measure phosphorylation-driven signaling activity (kinome responses) in wild ducks in the genus Anas.

Which animals/species are the focus of the tool development?

The project targets wild ducks within the genus Anas.

What is being measured with the peptide array?

The array is intended to detect phosphorylation-based changes across relevant pathways, capturing immune and metabolic signaling signatures (kinome responses).

Why is phosphorylation important in this project?

Phosphorylation is described as a core molecular switch cells use to control immune and metabolic pathways, so measuring phosphorylation-driven signaling can show how the host responds at the signaling level to infection or immune challenges.

What are the main research objectives?

There are two main objectives: (1) design and produce an Anas-tailored peptide array that captures immune and metabolic signaling signatures by detecting phosphorylation-based changes across relevant pathways; and (2) apply the tool to characterize cellular signal transduction responses when duck cells are challenged with avian influenza.

How will the newly developed tool be used in the project?

It will be applied to characterize cellular signal transduction responses when duck cells are challenged with avian influenza, helping define how infection influences immuno-metabolism and host defense signaling.

What pathogen or disease area is specifically mentioned?

Avian influenza is specifically mentioned as the challenge used to assess signaling responses.

How does this work relate to wild waterfowl and influenza?

The work is intended to support a better mechanistic understanding of avian influenza interactions with wild waterfowl, which are described as important natural hosts and reservoirs for influenza viruses.

What broader outcomes are mentioned for surveillance or management?

The description notes the work can inform surveillance or management strategies by clarifying host response biology.

How many awards are expected?

A single award is expected.

What is the maximum funding amount (award ceiling)?

The award ceiling is $47,000.

Is the funding level described as large or small?

It is described as modest and targeted.

What is the CFDA number associated with this opportunity?

The CFDA number is 15.808.

Who is eligible to apply?

Eligibility is listed broadly as "Others," with additional clarification referenced in the full announcement under an eligibility information section.

Does the eligibility description suggest any likely applicant types?

Yes. It suggests that only certain organizations may apply or may be preferred, often including CESU network partners such as universities, nonprofits, or other research institutions aligned with the CESU agreement.

Is this opportunity intended to fund general research, or a specialized project?

It is described as a small, specialized research award intended to produce a practical immunological tool (a duck-specific kinome peptide array) and generate early-stage or proof-of-concept biological findings on signaling responses to avian influenza in wild ducks.

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