Coordinating and Bioinformatics Unit for the Mouse Metabolic Phenotyping Centers and the Diabetic Complications Consortium (U24) | Apply Online

Opportunity Summary:

The grant opportunity titled "Coordinating and Bioinformatics Unit for the Mouse Metabolic Phenotyping Centers and the Diabetic Complications Consortium (U24)" (Funding Opportunity Number RFA-DK-15-011) is a National Institutes of Health (NIH) discretionary funding announcement that uses a cooperative agreement mechanism (U24). It is designed to support one awardee that will serve as a shared, central backbone for two NIDDK-supported research programs: the Mouse Metabolic Phenotyping Centers (MMPC) and the Diabetic Complications Consortium (DiaComp). The main idea is that these consortia generate complex, high-value datasets and rely on coordinated activities across multiple sites, and the NIH wants a dedicated unit to provide the informatics infrastructure and operational coordination that keeps the networks functioning efficiently and consistently.

At the center of the scope is the creation and ongoing operation of a Coordinating and Bioinformatics Unit (CBU). The CBU is expected to develop, host, and maintain the websites and databases used by MMPC and DiaComp, which typically means building reliable public-facing and internal-facing web resources, supporting data submission and retrieval workflows, and ensuring that databases remain functional, secure, and well organized over time. In practical terms, this involves not only initial development but also long-term maintenance: user support, routine updates, fixes, enhancements, documentation, uptime monitoring, and the kind of data stewardship required when multiple institutions are contributing information and expecting standardized access.

Beyond informatics, the CBU is also expected to handle major coordinating and administrative responsibilities for the combined programs. That includes organizing consortial meetings, which can involve planning agendas, logistics, coordination with NIH program staff and investigators, maintaining records and minutes, and supporting communication across the network. The CBU functions as the operational hub that helps the two consortia stay aligned, meet shared milestones, and maintain consistent procedures. Because this is a cooperative agreement, NIH is not just providing funds passively; the structure implies substantial NIH involvement and collaboration in how the work is carried out, which usually translates to regular interaction with NIH staff, reporting, and coordination around program priorities.

A distinctive responsibility in this opportunity is the requirement that the CBU distribute funds and provide financial management for "opportunity pool programs." In other words, the awardee is not only managing its own project budget but is also expected to administer and track the distribution of certain funds to support consortium-related activities or projects. That kind of role typically requires strong grants management capacity, transparent processes for allocating funds, documentation and tracking systems, and clear policies for compliance, reporting, and accountability. The CBU is therefore positioned as both an informatics core and an administrative and fiscal coordinating center.

In terms of timing and funding, the FOA was posted on July 17, 2015, with an original and current closing date of November 3, 2015, and an archive date of December 4, 2015. The estimated total funding listed is $11,090,000, and the award ceiling is $10,100,000, with an expected number of awards of 1. The CFDA number associated with the opportunity is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). No cost sharing or matching is required, which means applicants are not expected to provide non-federal matching funds as a condition of the award.

Eligibility is broad and includes many types of domestic U.S. organizations and government entities. Eligible applicants include nonprofit organizations (with and without 501(c)(3) status), public and private institutions of higher education, small businesses, for-profit organizations (including those other than small businesses), state and local governments (including county, city/township, special district governments, and independent school districts), and public housing authorities/Indian housing authorities. The eligibility list also explicitly includes a wide range of mission-based institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and regional organizations. At the same time, the FOA clearly excludes non-U.S. entities: foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed.

Overall, this opportunity is aimed at an institution or organization that can reliably operate as a national-level coordinating center, combining strong bioinformatics and web/database capabilities with proven administrative coordination and financial management. The awardee would be responsible for building and sustaining shared digital infrastructure, keeping consortium communications and meetings running smoothly, and administering a pool of funds to support program opportunities, all in support of the MMPC and DiaComp research missions under NIDDK. For applicants, the core challenge is demonstrating the operational maturity to serve two consortia at once: technical capacity to manage integrated data systems, organizational capacity to coordinate multi-site stakeholders, and fiscal capacity to manage and distribute funds in a compliant and transparent way.

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Previous opportunity: Mouse Metabolic Phenotyping Centers Consortium (U2C)

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