Opportunity Information: Apply for RFA CA 15 015
Apply for RFA CA 15 015
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Coordinating Center for Cancer Systems Biology Consortium (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.395 Cancer Treatment Research 93.396 Cancer Biology Research.
- This funding opportunity was created on Sep 2, 2015 and posted on Sep 2, 2015.
- Applicants must submit their applications by Sep 9, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,050,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: For profit organizations other than small businesses County governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Small businesses Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Coordinating Center for the Cancer Systems Biology Consortium (CSBC) (U24) opportunity, Funding Opportunity Number RFA-CA-15-015, is a National Cancer Institute (NCI) cooperative agreement designed to support the single, central coordinating hub for a larger, multi-award research consortium focused on cancer systems biology. The overall CSBC structure is intended to include one U24 Coordinating Center funded through this announcement, multiple U54 CSBC Research Centers funded through the companion announcement (RFA-CA-15-014), and additional related projects that may be supported through the U01 mechanism. The purpose of the consortium is to tackle the inherent complexity of cancer by combining experimental biology with computational and engineering approaches, including in silico modeling, multidimensional data analysis, and systems engineering methods that can integrate diverse biological measurements into predictive or mechanistic understanding relevant to basic and translational cancer research.
This specific U24 award is not primarily a stand-alone research project grant; it is meant to provide consortium-wide coordination, infrastructure, and support functions that allow the overall CSBC program to operate as a coherent, collaborative network rather than a set of disconnected projects. In practice, a coordinating center of this type typically serves as the operational backbone for communication across participating sites, harmonization of scientific and technical practices, facilitation of collaboration and data sharing, organization of meetings and working groups, tracking of milestones and progress, and dissemination of consortium outputs to the broader research community. Because the CSBC emphasizes the integration of experimental and computational efforts, the coordinating center role is especially important for aligning data standards, supporting model and data exchange, encouraging reproducibility, and ensuring that consortium-wide products (for example, datasets, models, software, protocols, or other community resources) are discoverable and usable beyond the immediate awardees.
The funding instrument is a cooperative agreement (U24), which generally means NCI expects to have substantial programmatic involvement compared with a standard research project grant. The announcement is categorized as discretionary, with an activity area listed under education and health, and it is tied to the NIH CFDA listings 93.395 (Cancer Treatment Research) and 93.396 (Cancer Biology Research. The program anticipated making one award in total, reflecting the intent to establish a single coordinating center for the consortium. The estimated total funding level listed is $1,050,000, with an award ceiling of $750,000, and there is no cost sharing or matching requirement.
Eligibility is broad across U.S.-based organizational types, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions in those categories where specified), for-profit organizations other than small businesses, small businesses, state and county governments, and other entities as described in the additional eligibility information. The opportunity explicitly includes a wide range of institution types often emphasized in federal eligibility language, such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and AANAPISI institutions, along with eligible federal agencies and U.S. territories or possessions. Foreign institutions (non-U.S. entities) and non-U.S. components of U.S. organizations are not eligible to apply, although foreign components as defined in the NIH Grants Policy Statement are allowed, which typically means certain project elements may be carried out abroad under NIH rules even though the applicant organization must be U.S.-based.
Key dates in the listing show the opportunity was posted and created on September 2, 2015, with an original and current closing date of September 9, 2016, and an archive date of October 10, 2016. The agency is the National Institutes of Health, with the NCI as the sponsoring institute. The full announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-15-015.html, and the listing provides NIH Office of Extramural Research (OER) webmaster contacts for technical issues accessing or linking to the announcement.
FAQs: Coordinating Center for the Cancer Systems Biology Consortium (CSBC) (U24) - RFA-CA-15-015
What is this funding opportunity?
This opportunity is the Coordinating Center for the Cancer Systems Biology Consortium (CSBC) (U24), Funding Opportunity Number RFA-CA-15-015. It is a National Cancer Institute (NCI) cooperative agreement intended to support a single, central coordinating hub for a larger multi-award research consortium focused on cancer systems biology.
Which agency is offering the award?
The agency is the National Institutes of Health (NIH), with the National Cancer Institute (NCI) as the sponsoring institute.
What activity mechanism is used?
The funding instrument is a cooperative agreement using the U24 activity code.
What does it mean that this is a cooperative agreement (U24)?
A cooperative agreement generally indicates that NCI expects to have substantial programmatic involvement compared with a standard research project grant. This aligns with the coordinating role of the award, where consortium-wide operations and alignment are central.
Is this U24 meant to be a stand-alone research project grant?
No. This U24 award is not primarily intended to be a stand-alone research project grant. It is designed to provide consortium-wide coordination, infrastructure, and support functions so the overall CSBC operates as a coherent, collaborative network.
What is the purpose of the Cancer Systems Biology Consortium (CSBC)?
The purpose of the consortium is to address the inherent complexity of cancer by combining experimental biology with computational and engineering approaches. This includes in silico modeling, multidimensional data analysis, and systems engineering methods to integrate diverse biological measurements into predictive or mechanistic understanding relevant to basic and translational cancer research.
How is the overall CSBC program structured?
The intended structure includes one U24 Coordinating Center funded through this announcement (RFA-CA-15-015), multiple U54 CSBC Research Centers funded through the companion announcement (RFA-CA-15-014), and additional related projects that may be supported through the U01 mechanism.
How many awards were anticipated?
The program anticipated making one award in total, reflecting the intent to establish a single coordinating center for the consortium.
What kinds of activities would a coordinating center typically support?
Based on the description provided, a coordinating center typically serves as the operational backbone for: communication across participating sites; harmonization of scientific and technical practices; facilitation of collaboration and data sharing; organization of meetings and working groups; tracking milestones and progress; and dissemination of consortium outputs to the broader research community.
Why is the coordinating center especially important for CSBC?
Because CSBC emphasizes integrating experimental and computational efforts, the coordinating center role is particularly important for aligning data standards, supporting model and data exchange, encouraging reproducibility, and ensuring consortium-wide products are discoverable and usable beyond the immediate awardees.
What kinds of consortium outputs are mentioned?
Examples listed include datasets, models, software, protocols, and other community resources.
What is the estimated total funding level and the award ceiling?
The estimated total funding level listed is $1,050,000, and the award ceiling is $750,000.
Is cost sharing or matching required?
No. The listing states there is no cost sharing or matching requirement.
What is the opportunity category and activity area?
The announcement is categorized as discretionary, with an activity area listed under education and health.
Which CFDA (NIH program) listings are associated with this opportunity?
The opportunity is tied to NIH CFDA listings 93.395 (Cancer Treatment Research) and 93.396 (Cancer Biology Research).
Who is eligible to apply (in general)?
Eligibility is broad across U.S.-based organizational types, including: public and state-controlled institutions of higher education; private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (as described in the eligibility language); for-profit organizations other than small businesses; small businesses; state and county governments; and other entities as described in the additional eligibility information.
Are minority-serving institutions specifically included?
Yes. The opportunity explicitly includes a wide range of institution types commonly referenced in federal eligibility language, including HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and AANAPISI institutions.
Are U.S. territories or possessions eligible?
Yes. The eligibility language explicitly includes U.S. territories or possessions, along with eligible federal agencies.
Are foreign institutions eligible to apply?
No. Foreign institutions (non-U.S. entities) and non-U.S. components of U.S. organizations are not eligible to apply.
Are foreign components allowed at all?
Yes. The information provided states that foreign components (as defined in the NIH Grants Policy Statement) are allowed, meaning certain project elements may be carried out abroad under NIH rules, even though the applicant organization must be U.S.-based.
What are the key dates for this opportunity?
The listing shows it was posted and created on September 2, 2015. The original and current closing date is September 9, 2016. The archive date is October 10, 2016.
Where can applicants find the full announcement?
The full announcement is available through the NIH grants guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-15-015.html
Who is listed for technical help accessing or linking to the announcement?
The listing provides NIH Office of Extramural Research (OER) webmaster contacts for technical issues related to accessing or linking to the announcement.
What is the companion funding opportunity for the U54 Research Centers?
The companion announcement for the U54 CSBC Research Centers is RFA-CA-15-014.
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Previous opportunity: Research Centers for Cancer Systems Biology Consortium(U54)
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