Opportunity Information: Apply for PAR 22 120
Apply for PAR 22 120
- The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Coordinating Center to Support Research on Community Level Interventions for Firearm and Related Violence, Injury and Mortality Prevention (CLIF-VP) (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.273, 93.307, 93.313, 93.361, 93.865, 93.866.
- This funding opportunity was created on 2022-03-04.
- Applicants must submit their applications by 2022-04-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Opportunity Summary:
The NIH funding opportunity PAR 22-120 seeks a single Coordinating Center (CC) to anchor and support a larger, multi-site research effort called the Community-Level Interventions for Firearm Violence Prevention (CLIF-VP) Research Network. The central goal of the network is to build stronger evidence on how to prevent firearm and related violence, injury, and death by developing and testing interventions that operate at the community level or within community organizations (rather than focusing only on individual-level clinical approaches). This is a cooperative agreement (U24), meaning the awardee is expected to work closely and continuously with NIH program staff as an active partner in shaping, coordinating, and advancing the network's work. Clinical trials are not allowed under this specific U24 mechanism.
The CLIF-VP Research Network is structured as a hub-and-spoke model. The Coordinating Center funded through this announcement serves as the hub, while up to 10 separate Research Projects serve as the spokes. Those Research Projects are funded through a companion phased cooperative agreement mechanism (UG3/UH3). Under that companion structure, each Research Project begins in a planning and readiness phase (Phase 1, typically 1 to 2 years) where teams must demonstrate they have the preparation, feasibility, partnerships, and operational capacity needed to run their proposed community intervention study. Projects that meet predefined milestones transition into Phase 2, where they implement and evaluate the intervention. The Coordinating Center is expected to make the overall network function as a coherent program rather than a collection of isolated studies, helping to standardize approaches where appropriate while still allowing projects to address different communities, contexts, and strategies.
The CC's responsibilities are organized into three main domains. First, it provides administration, coordination, and communication support. In practical terms, this includes setting up governance structures, scheduling and running network meetings, supporting NIH-required reporting and progress tracking, facilitating collaboration across projects, and making sure decisions and information flow efficiently among all partners. Second, it provides data, measurement, and analytic support and consultation. That typically means helping the network align on core measures, improving data quality and comparability across projects, advising on study design and analytic plans appropriate for community-level intervention research, and supporting cross-project analyses or harmonized data elements when feasible. Third, it provides public and stakeholder engagement plus dissemination support. This component emphasizes meaningful engagement with community partners and stakeholders and also focuses on communicating findings in ways that can be used by practitioners, community organizations, and policy or public health audiences, not just academic publication channels.
Eligibility is broad and includes many types of U.S.-based organizations that could credibly run a national research coordinating function. Eligible applicants include state, county, city, township, and special district governments; independent school districts; public and private institutions of higher education; federally recognized tribal governments; tribal organizations (other than federally recognized governments); public housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and additional categories highlighted in the announcement such as HBCUs, Hispanic-serving institutions, AANAPISISs, tribally controlled colleges and universities, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. At the same time, the FOA is explicit that foreign entities are not eligible: non-U.S. organizations cannot apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
The award instrument is a cooperative agreement and the stated award ceiling is $1,500,000, reflecting the scale of the coordinating role and the expectation that the CC will provide network-wide infrastructure and expertise rather than conduct a single discrete research study. The original closing date listed for this opportunity was April 22, 2022, and the sponsoring agency is the National Institutes of Health. The funding activity is categorized under education, health, income security, and social services, and it is associated with multiple CFDA numbers (93.213, 93.273, 93.307, 93.313, 93.361, 93.865, 93.866), reflecting NIH's multi-institute participation in violence prevention, injury prevention, and related public health research.
Overall, this opportunity is best understood as NIH investing in the backbone infrastructure for a national research network focused on real-world, community-level strategies to reduce firearm and related violence. The Coordinating Center is expected to keep the network organized, strengthen the scientific and analytic rigor across projects, and ensure that community engagement and dissemination are strong enough that the research can translate into practical prevention approaches once the studies are completed.
FAQs: NIH PAR-22-120 Coordinating Center for the CLIF-VP Research Network
What is PAR-22-120?
PAR-22-120 is a National Institutes of Health (NIH) funding opportunity announcement seeking one Coordinating Center (CC) to anchor and support the Community-Level Interventions for Firearm Violence Prevention (CLIF-VP) Research Network.
What is the CLIF-VP Research Network?
The CLIF-VP Research Network is a larger, multi-site research effort designed to build stronger evidence about how to prevent firearm and related violence, injury, and death by developing and testing interventions that operate at the community level or within community organizations.
What is the primary goal of this network?
The primary goal is to strengthen the evidence base for community-level strategies to prevent firearm and related violence, injury, and death, emphasizing interventions implemented in real-world community contexts rather than focusing only on individual-level clinical approaches.
What does NIH mean by "community-level interventions" in this context?
Based on the opportunity description, community-level interventions are strategies that operate at the level of communities or within community organizations (instead of only individual-level clinical approaches). These interventions are intended to address firearm and related violence prevention in community settings.
What is being funded under PAR-22-120?
This announcement funds a single Coordinating Center (CC). The CC serves as the hub that supports and coordinates a broader network of up to 10 separate Research Projects (the spokes).
How is the CLIF-VP Research Network structured?
The network is structured as a hub-and-spoke model. The Coordinating Center is the hub, and up to 10 separate Research Projects are the spokes.
Are the Research Projects funded by this same announcement?
No. The Research Projects are funded through a companion phased cooperative agreement mechanism (UG3/UH3). PAR-22-120 specifically supports the Coordinating Center role.
What is the UG3/UH3 phased structure for the companion Research Projects?
Each Research Project begins with a planning and readiness phase (Phase 1, typically 1 to 2 years) where teams must demonstrate preparation, feasibility, partnerships, and operational capacity for their community intervention study. Projects that meet predefined milestones transition into Phase 2 to implement and evaluate the intervention.
What is the funding mechanism for the Coordinating Center?
The Coordinating Center is funded as a cooperative agreement under the U24 mechanism.
What does it mean that this is a cooperative agreement (U24)?
A cooperative agreement means the awardee is expected to work closely and continuously with NIH program staff as an active partner in shaping, coordinating, and advancing the network's work.
Are clinical trials allowed under this U24 opportunity?
No. Clinical trials are not allowed under this specific U24 mechanism.
What is the Coordinating Center expected to do for the network overall?
The Coordinating Center is expected to make the network function as a coherent program rather than a collection of isolated studies, helping to standardize approaches where appropriate while still allowing projects to address different communities, contexts, and strategies.
What are the main responsibility areas of the Coordinating Center?
The Coordinating Center responsibilities are organized into three domains: (1) administration, coordination, and communication support; (2) data, measurement, and analytic support and consultation; and (3) public and stakeholder engagement plus dissemination support.
What does "administration, coordination, and communication support" include?
This includes setting up governance structures, scheduling and running network meetings, supporting NIH-required reporting and progress tracking, facilitating collaboration across projects, and ensuring decisions and information flow efficiently among partners.
What does "data, measurement, and analytic support and consultation" include?
This typically includes helping the network align on core measures, improving data quality and comparability across projects, advising on study design and analytic plans appropriate for community-level intervention research, and supporting cross-project analyses or harmonized data elements when feasible.
What does "public and stakeholder engagement plus dissemination support" include?
This emphasizes meaningful engagement with community partners and stakeholders and focuses on communicating findings in ways usable by practitioners, community organizations, and policy or public health audiences, not only through academic publication channels.
Who can apply for this opportunity?
Eligibility is broad for U.S.-based organizations capable of running a national research coordinating function. Eligible applicants include various government entities, educational institutions, tribal governments and organizations, public housing authorities, nonprofits, for-profits (including small businesses and other than small businesses), and additional categories highlighted in the announcement such as HBCUs, Hispanic-serving institutions, AANAPISISs, tribally controlled colleges and universities, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
Can a state, county, or city government apply?
Yes. State, county, city, township, and special district governments are listed as eligible applicants.
Can an independent school district apply?
Yes. Independent school districts are listed as eligible applicants.
Can colleges and universities apply?
Yes. Public and private institutions of higher education are eligible. The announcement also highlights specific institution types such as HBCUs, Hispanic-serving institutions, AANAPISISs, and tribally controlled colleges and universities.
Can tribal entities apply?
Yes. Federally recognized tribal governments are eligible, and tribal organizations (other than federally recognized governments) are also included among eligible applicants.
Can nonprofits apply?
Yes. Nonprofits are eligible, including both 501(c)(3) and non-501(c)(3) organizations.
Can for-profit organizations apply?
Yes. For-profit organizations (other than small businesses) and small businesses are both included among eligible applicants.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are specifically highlighted among eligible categories in the announcement.
Are U.S. territories eligible to apply?
Yes. U.S. territories or possessions are listed among eligible applicants.
Are foreign organizations eligible to apply?
No. The opportunity explicitly states that foreign entities are not eligible.
Can a non-U.S. component of a U.S. organization apply or participate as eligible applicant?
No. Non-U.S. components of U.S. organizations are not eligible under this opportunity, based on the information provided.
Are foreign components allowed in any form?
No. Foreign components (as defined by NIH policy) are not allowed.
What is the award instrument and why does it matter?
The award instrument is a cooperative agreement (U24). This matters because the Coordinating Center is expected to work closely and continuously with NIH program staff as an active partner, rather than operating fully independently.
What is the award ceiling for this Coordinating Center?
The stated award ceiling is $1,500,000.
Why is the award ceiling set at this level?
The ceiling reflects the scale of the coordinating role and the expectation that the Coordinating Center will provide network-wide infrastructure and expertise, rather than conducting a single discrete research study.
What is the sponsoring agency for this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What was the original closing date listed for this opportunity?
The original closing date listed was April 22, 2022.
What funding activity categories are associated with this opportunity?
The funding activity is categorized under education, health, income security, and social services.
Which CFDA numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA numbers: 93.213, 93.273, 93.307, 93.313, 93.361, 93.865, 93.866.
How should applicants think about the role of the Coordinating Center in plain terms?
This opportunity is best understood as NIH investing in the backbone infrastructure for a national research network focused on community-level strategies to reduce firearm and related violence. The Coordinating Center is expected to keep the network organized, strengthen scientific and analytic rigor across projects, and ensure community engagement and dissemination are strong enough to translate research into practical prevention approaches when studies are completed.
Is the Coordinating Center expected to run its own standalone intervention study?
The description emphasizes that the Coordinating Center provides network-wide infrastructure and expertise and helps the overall network function as a coherent program. The focus is on coordination and support across the network rather than conducting one isolated study.
Does the Coordinating Center help standardize work across projects?
Yes. The Coordinating Center is expected to help standardize approaches where appropriate, while still allowing individual Research Projects to address different communities, contexts, and strategies.
Does the Coordinating Center support cross-project or harmonized analyses?
Yes. The data, measurement, and analytic support role includes supporting cross-project analyses or harmonized data elements when feasible.
Who are the intended audiences for dissemination under this opportunity?
Dissemination is intended to reach practitioners, community organizations, and policy or public health audiences, not only academic publication channels.
What kinds of engagement expectations are included for the Coordinating Center?
The opportunity emphasizes meaningful engagement with community partners and stakeholders as part of the Coordinating Center's responsibilities.
How many total Research Projects may be part of the network?
The network includes up to 10 separate Research Projects as spokes, coordinated by the single Coordinating Center.
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|---|
| Research on Community Level Interventions for Firearm and Related Violence, Injury and Mortality Prevention (CLIF-VP) (UG3/UH3 Clinical Trial Optional) Apply for PAR 22 115 Funding Number: PAR 22 115 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Integration and Analysis of BRAIN Initiative Data (R01 Clinical Trial Not Allowed) Apply for RFA MH 22 220 Funding Number: RFA MH 22 220 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trial Required) Apply for RFA OD 22 010 Funding Number: RFA OD 22 010 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) Apply for RFA OD 22 009 Funding Number: RFA OD 22 009 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $6,000,000 |
| INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) Apply for RFA OD 22 007 Funding Number: RFA OD 22 007 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $275,000 |
| Small Research Grants for Analysis, Curation, and/or Sharing of Down syndrome-related Research Data for the INCLUDE Project (R03 Clinical Trial Not Allowed) Apply for RFA OD 22 008 Funding Number: RFA OD 22 008 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| HEAL Initiative: Team Research for Initial Translational Efforts in Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed) Apply for RFA NS 22 052 Funding Number: RFA NS 22 052 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Clinical Trial Not Allowed) Apply for RFA NS 22 040 Funding Number: RFA NS 22 040 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (U01 Basic Experimental Studies with Humans Required) Apply for RFA NS 22 041 Funding Number: RFA NS 22 041 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Team-Research BRAIN Circuit Programs - TeamBCP (U19 Basic Experimental Studies with Humans Required) Apply for RFA NS 22 039 Funding Number: RFA NS 22 039 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Transformative Brain Non-invasive Imaging Technology Development (UG3/UH3 Clinical Trial Not Allowed) Apply for RFA EB 22 001 Funding Number: RFA EB 22 001 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy (MIRHIQL): Resource Center (U24- Clinical Trial Optional) Apply for RFA DA 23 042 Funding Number: RFA DA 23 042 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| HEAL Initiative: Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy (MIRHIQL) (R01 Clinical Trial Required) Apply for RFA DA 23 041 Funding Number: RFA DA 23 041 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $750,000 |
| Prevention and Treatment through a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings Implementation Science Network (PATCH-IN) Clinical Research Centers (UG1 Clinical Trial Optional) Apply for RFA HD 23 013 Funding Number: RFA HD 23 013 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PATC3H Implementation Science Network (PATC3H-IN) Coordination, Translation and Advanced Methods and Analytics Center (UM2 Clinical Trial Optional) Apply for RFA HD 23 014 Funding Number: RFA HD 23 014 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $25,000,000 |
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| BRAIN Initiative: Brain Behavior Quantification and Synchronization (R61/R33 Clinical Trial Optional) Apply for RFA MH 22 240 Funding Number: RFA MH 22 240 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R33 Clinical Trial Optional) Apply for RFA DA 23 054 Funding Number: RFA DA 23 054 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $750,000 |
| HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional) Apply for RFA DA 23 053 Funding Number: RFA DA 23 053 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $750,000 |
| HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed) Apply for RFA EB 22 002 Funding Number: RFA EB 22 002 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $750,000 |
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