Opportunity Information: Apply for RFA CA 10 501
Apply for RFA CA 10 501
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Coordination Center for Transdisciplinary Research in Energetics and Cancer (Limited Competition U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.399 Cancer Control.
- This funding opportunity was created on Dec 3, 2009 and posted on Dec 3, 2009.
- Applicants must submit their applications by Feb 26, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
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Opportunity Summary:
The Coordination Center for Transdisciplinary Research in Energetics and Cancer (TREC) (Limited Competition U01) is a National Institutes of Health, National Cancer Institute funding opportunity designed to keep the TREC network functioning as a coordinated, collaborative research program focused on the connections between energetics and cancer. In plain terms, it supports the central hub that helps multiple TREC Research Centers work together across disciplines studying how nutrition, physical activity, energy balance, obesity, and related behavioral and environmental factors influence cancer risk and outcomes. The Coordination Center is meant to strengthen teamwork and integration across a wide range of science, from basic and mechanistic work (including biology, genomics, and genetics related to energy balance) all the way to behavioral, sociocultural, and environmental influences on diet, activity, body weight, and cancer.
This particular announcement is a limited competition renewal, meaning it was only seeking an application from the existing Coordination Center awardee rather than opening competition broadly to new applicants. The Coordination Center's core responsibilities include organizing and supporting collaboration among the TREC Research Centers, convening semi-annual meetings of TREC investigators to share findings and align priorities, developing training modules to build shared methods and transdisciplinary skills across the network, and evaluating progress across the initiative. The overall idea is that the science is too complex for isolated projects, so the Coordination Center provides structure, shared activities, and ongoing assessment so that discoveries in one area (for example, molecular pathways related to energy balance) can inform and be informed by work in population health, community interventions, and policy.
The larger TREC initiative, which this Coordination Center supports, is framed around two major goals. First, it aims to deepen understanding of the mechanisms that link energy balance with carcinogenesis, spanning a broad continuum that can include animal models, genetics and genomics, and research across stages from cancer causation to prevention. Second, it aims to better understand and integrate the causes of obesity-related behaviors using health behavior theory, with an emphasis on interventions and approaches that can have broad population impact at social, environmental, and policy levels. Within that second goal, there is a clear focus on groups where the burden and stakes are high, including children, populations at elevated risk for obesity, and cancer survivors.
In terms of funding structure, the award uses the NIH Cooperative Agreement Specialized Centers mechanism (U01). A cooperative agreement generally signals that NIH expects substantial programmatic involvement during the award period, reflecting the hands-on coordination and network management role of the funded center. This Coordination Center FOA is paired with a separate funding opportunity that supports the TREC Research Centers themselves under a different mechanism (U54), reinforcing that the Coordination Center is the connective infrastructure for a set of separately funded research hubs.
Financially, NCI indicated an intention to commit about $2 million in total costs for FY2010 and approximately $10 million in total costs over a five-year project period, with one Coordination Center award expected. The opportunity did not require cost sharing or matching. The FOA was posted December 3, 2009, with a closing date of February 26, 2010, and later archived March 29, 2010. The associated CFDA listings were 93.393 (Cancer Cause and Prevention Research) and 93.399 (Cancer Control). Eligible applicant categories listed in the source data include nonprofit organizations (with and without 501(c)(3) status) and public or private institutions of higher education, although the limited-competition nature of the FOA meant the practical applicant pool was restricted to the incumbent Coordination Center.
Administrative details include the funding opportunity number RFA-CA-10-501 and an NIH Office of Extramural Research webmaster contact for technical access issues. The full announcement was hosted on the NIH grants site, with additional information available via the linked RFA page.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is the "Coordination Center for Transdisciplinary Research in Energetics and Cancer (TREC) (Limited Competition U01)" from the National Institutes of Health (NIH), National Cancer Institute (NCI). It supports the central Coordination Center that keeps the broader TREC network operating as a coordinated, collaborative research program focused on links between energetics and cancer.
What does "TREC" stand for, and what is the program about?
TREC stands for Transdisciplinary Research in Energetics and Cancer. The overall program focuses on how factors tied to energy balance (including nutrition, physical activity, obesity, and related behavioral and environmental influences) relate to cancer risk and cancer outcomes, and how discoveries can be integrated across different scientific fields.
What is the Coordination Center meant to do?
The Coordination Center functions as the network hub that helps multiple TREC Research Centers work together. It is designed to strengthen teamwork and integration across a wide range of science, from basic and mechanistic research (including biology, genomics, and genetics related to energy balance) to behavioral, sociocultural, and environmental influences on diet, activity, body weight, and cancer.
What are the core responsibilities of the Coordination Center under this FOA?
Based on the information provided, the Coordination Center responsibilities include:
- Organizing and supporting collaboration among the TREC Research Centers
- Convening semi-annual meetings of TREC investigators to share findings and align priorities
- Developing training modules to build shared methods and transdisciplinary skills across the network
- Evaluating progress across the TREC initiative
Why does NCI fund a Coordination Center instead of only funding individual research projects?
The TREC science is described as too complex for isolated projects. The Coordination Center provides structure, shared activities, and ongoing assessment so that discoveries in one area (for example, molecular pathways related to energy balance) can inform, and be informed by, work in population health, community interventions, and policy.
What kinds of research areas does the TREC network connect?
The network is designed to connect work across the full continuum described in the opportunity, including basic and mechanistic work (such as biology, genomics, and genetics related to energy balance) and behavioral, sociocultural, environmental, and policy-related influences on diet, physical activity, body weight, and cancer.
What are the two major goals of the larger TREC initiative?
The initiative is framed around two major goals:
- Deepen understanding of the mechanisms linking energy balance with carcinogenesis across a broad continuum (which can include animal models, genetics and genomics, and research spanning stages from cancer causation to prevention).
- Better understand and integrate the causes of obesity-related behaviors using health behavior theory, emphasizing interventions and approaches with broad population impact at social, environmental, and policy levels.
Which populations are specifically emphasized within the initiative's obesity-related behavior goal?
Within the second goal, the focus includes groups where burden and stakes are high, including children, populations at elevated risk for obesity, and cancer survivors.
What funding mechanism does this opportunity use?
The award uses the NIH Cooperative Agreement Specialized Centers mechanism (U01).
What does it mean that this is a "cooperative agreement" (U01)?
A cooperative agreement generally indicates substantial programmatic involvement by NIH during the award period. In this case, that aligns with the hands-on coordination and network management role expected of the funded Coordination Center.
How does this Coordination Center opportunity relate to the TREC Research Centers?
This FOA supports the Coordination Center, described as the connective infrastructure for a set of separately funded research hubs. The Coordination Center FOA is paired with a separate funding opportunity that supports the TREC Research Centers under a different mechanism (U54).
Is this opportunity open to new applicants?
No. This particular announcement is described as a limited competition renewal. It sought an application only from the existing (incumbent) Coordination Center awardee rather than opening competition broadly to new applicants.
Who was listed as eligible to apply in the source data?
The eligible applicant categories listed include nonprofit organizations (with and without 501(c)(3) status) and public or private institutions of higher education. However, the limited-competition nature of the FOA meant the practical applicant pool was restricted to the incumbent Coordination Center.
How many awards were expected?
One Coordination Center award was expected.
How much funding did NCI plan to commit?
NCI indicated an intention to commit about $2 million in total costs for FY2010 and approximately $10 million in total costs over a five-year project period.
Does this FOA require cost sharing or matching?
No cost sharing or matching was required.
What is the funding opportunity number?
The funding opportunity number is RFA-CA-10-501.
When was the FOA posted and when did it close?
The FOA was posted on December 3, 2009. The closing date was February 26, 2010.
Is this funding opportunity still active?
No. The opportunity was later archived on March 29, 2010.
What CFDA listings are associated with this opportunity?
The associated CFDA listings were 93.393 (Cancer Cause and Prevention Research) and 93.399 (Cancer Control).
Where was the full announcement hosted and where could applicants find more details?
The full announcement was hosted on the NIH grants site, with additional information available via the linked RFA page.
Who was the contact for technical access issues?
The administrative details referenced an NIH Office of Extramural Research webmaster contact for technical access issues.
What is the plain-language purpose of funding this Coordination Center?
In plain terms, it supports the central hub that helps multiple TREC Research Centers work together across disciplines to study how nutrition, physical activity, energy balance, obesity, and related behavioral and environmental factors influence cancer risk and outcomes.
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