Opportunity Information: Apply for RFA AR 11 011

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Core Centers for Musculoskeletal Biology and Medicine (P30)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.846 Arthritis, Musculoskeletal and Skin Diseases Research.
  • This funding opportunity was created on May 26, 2010 and posted on May 26, 2010.
  • Applicants must submit their applications by Oct 1, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,800,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $400,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses County governments Independent school districts City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Public housing authorities/Indian housing authorities Special district governments Native American tribal governments (Federally recognized) State governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Core Centers for Musculoskeletal Biology and Medicine (CCMBM) (P30) is a National Institutes of Health funding opportunity issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to support centralized research infrastructure in musculoskeletal biology and medicine. The main goal is to strengthen and accelerate ongoing, high-quality research by funding shared core facilities and services that multiple investigators can use. Rather than paying for individual research projects, this program focuses on building and maintaining the resources that make many projects more efficient and productive, especially for groups of established investigators who already hold active, peer-reviewed research funding in musculoskeletal-related areas.

This opportunity uses the NIH P30 Research Core Center Grant mechanism, which is specifically designed to support research centers that provide shared resources, technical services, and collaborative infrastructure. In practical terms, a funded center would typically offer specialized cores (for example, imaging, biomechanics, histology, animal models, biomaterials testing, biostatistics, genomics/proteomics, cell and tissue culture, clinical sample processing, or other domain-specific capabilities aligned with musculoskeletal science). The expectation is that consolidating these capabilities into well-run, accessible shared cores reduces duplication across labs, improves quality control and standardization, lowers per-project costs, and speeds up the pace of discovery by giving investigators reliable access to advanced tools and expertise.

NIAMS anticipated making up to three awards under this solicitation, including both new awards and competing continuation grants. The total estimated funding listed is about $1.8 million, and the announcement notes that up to $1.2 million in direct costs may be awarded in support of the solicitation. The source data also lists an award ceiling of $400,000, indicating a limit that may apply per award year or per budget period depending on NIH budgeting and the specifics of the FOA; applicants would need to follow the detailed instructions in the full announcement for allowable budgets and how caps are applied. No cost sharing or matching is required.

The applicant pool is broad and includes many organization types that NIH commonly allows for center grants. Eligible applicants include public and private institutions of higher education, nonprofits (with and without 501(c)(3) status), small businesses, other for-profit organizations (other than small businesses), state and local governments (including county and city/township governments), independent school districts, special district governments, public housing authorities/Indian housing authorities, Native American tribal governments (both federally recognized and other than federally recognized), and additional categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. This breadth reflects the idea that strong musculoskeletal research programs and core facilities can be housed in many kinds of research environments, as long as they can demonstrate a critical mass of active, funded investigators who will use the cores and benefit from centralized resources.

Administratively, the opportunity is a discretionary grant in the health funding activity category, associated with CFDA 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research). It was posted on May 26, 2010, with an original and current closing date of October 1, 2010, and an archive date of November 1, 2010, meaning it is a historical (archived) announcement rather than an open competition today. The official funding opportunity number is RFA-AR-11-011, and the full announcement was hosted through the NIH grants website. For access or technical issues related to the electronic posting, the listed contact was the NIH Office of Extramural Research (OER) webmaster.

In summary, this NIAMS P30 program was designed to fund musculoskeletal-focused research core centers that serve multiple already-funded investigators by providing shared, high-value services and facilities. The intent is to create an efficient, collaborative research environment that increases productivity and speeds progress in musculoskeletal biology and medicine through well-managed, widely used core resources rather than through funding individual research aims.

Frequently Asked Questions (FAQs): Core Centers for Musculoskeletal Biology and Medicine (CCMBM) (P30)

What is the CCMBM (P30) funding opportunity?

The Core Centers for Musculoskeletal Biology and Medicine (CCMBM) (P30) is a National Institutes of Health (NIH) funding opportunity issued by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). It supports centralized research infrastructure for musculoskeletal biology and medicine by funding shared core facilities and services used by multiple investigators.

What is the main purpose of this program?

The main goal is to strengthen and accelerate ongoing, high-quality musculoskeletal research by supporting shared resources (core facilities and services). The program is intended to reduce duplication across laboratories, improve standardization and quality control, lower per-project costs, and speed discovery by providing reliable access to specialized tools and expertise.

Does this program fund individual research projects?

No. This opportunity is focused on building and maintaining shared research infrastructure rather than paying for individual research projects. It is designed to support cores and center infrastructure that make many projects more efficient and productive.

What NIH grant mechanism is used for this opportunity?

This opportunity uses the NIH P30 Research Core Center Grant mechanism. P30 awards are designed to support research centers that provide shared resources, technical services, and collaborative infrastructure for groups of investigators.

What kinds of core facilities or services might a funded center provide?

A funded center would typically provide specialized shared cores aligned with musculoskeletal science. Examples mentioned include imaging, biomechanics, histology, animal models, biomaterials testing, biostatistics, genomics/proteomics, cell and tissue culture, clinical sample processing, and other domain-specific capabilities relevant to musculoskeletal biology and medicine.

Who is this program designed to serve?

The program is designed to support groups of established investigators who already have active, peer-reviewed research funding in musculoskeletal-related areas and who will use shared cores and services supported by the center.

How many awards were anticipated under this solicitation?

NIAMS anticipated making up to three awards under this solicitation, including both new awards and competing continuation grants.

How much funding was associated with this announcement?

The announcement lists total estimated funding of about $1.8 million, and it notes that up to $1.2 million in direct costs may be awarded in support of the solicitation.

Is there an award ceiling or cap mentioned?

Yes. The source data lists an award ceiling of $400,000. The announcement notes that this limit may apply per award year or per budget period depending on NIH budgeting and the specifics of the funding opportunity announcement (FOA). Applicants would need to follow the full FOA instructions for how budget limits and caps are applied.

Is cost sharing or matching required?

No. No cost sharing or matching is required for this opportunity.

What types of organizations were eligible to apply?

The eligible applicant pool is broad and includes many organization types. Examples listed include public and private institutions of higher education; nonprofits (with and without 501(c)(3) status); small businesses; other for-profit organizations (other than small businesses); state and local governments (including county and city/township governments); independent school districts; special district governments; public housing authorities/Indian housing authorities; Native American tribal governments (federally recognized and other than federally recognized); Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; regional organizations; eligible federal agencies; and U.S. territories or possessions.

What is the research focus area for this center program?

The program is focused on musculoskeletal biology and medicine and is intended to support shared infrastructure that advances musculoskeletal-related research supported by multiple investigators.

What funding activity category and assistance listing (CFDA) is associated with this opportunity?

It is described as a discretionary grant in the health funding activity category and is associated with CFDA 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research).

What is the official funding opportunity number (FOA number)?

The official funding opportunity number listed is RFA-AR-11-011.

When was this opportunity posted and when did it close?

It was posted on May 26, 2010. The original and current closing date listed is October 1, 2010.

Is this funding opportunity still open?

No. The archive date is listed as November 1, 2010, meaning this is a historical (archived) announcement rather than an open competition today.

What does it mean that this is an archived announcement?

Based on the provided information, an archive date indicates the announcement is no longer active and is kept for historical reference rather than accepting current applications.

Where was the full announcement hosted?

The full announcement was hosted through the NIH grants website.

Who was listed as the contact for access or technical issues?

For access or technical issues related to the electronic posting, the listed contact was the NIH Office of Extramural Research (OER) webmaster.

Why does NIAMS support core centers rather than funding only individual labs?

The intent is to create an efficient, collaborative research environment by centralizing high-value services and facilities. The expectation is that shared cores reduce duplication across labs, improve standardization and quality control, lower per-project costs, and accelerate progress by providing broad access to advanced tools and expertise.

What is the overall takeaway of this NIAMS P30 CCMBM program?

It was designed to fund musculoskeletal-focused research core centers that serve multiple already-funded investigators through shared, well-managed core resources and services, with the goal of increasing productivity and speeding advances in musculoskeletal biology and medicine.

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