Opportunity Information: Apply for PAR 15 104
Apply for PAR 15 104
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research.
- This funding opportunity was created on Jan 29, 2015 and posted on Jan 29, 2015.
- Applicants must submit their applications by Mar 10, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $2,500,000.00 in funding.
- Eligible applicants include: County governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Independent school districts Special district governments Public and State controlled institutions of higher education State governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The grant opportunity titled Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (U01) (Funding Opportunity Number PAR 15 104) is a National Institutes of Health program led by the National Cancer Institute (NCI) to strengthen and modernize the backbone of cancer epidemiology cohort research. It is set up as a cooperative agreement (U01), which typically means applicants should expect an active partnership with NCI program staff rather than a hands-off award. The central purpose is to provide targeted infrastructure support for the core functions that make Cancer Epidemiology Cohorts (CECs) run effectively, while also encouraging methodological research that improves how these cohorts are designed, maintained, and used for cancer prevention and population science.
In practical terms, the FOA is aimed at the foundational pieces that allow a cohort to generate reliable, high-value data over time. That includes support for existing cohorts as well as the establishment or strengthening of new cohorts, with an emphasis on core operational capacity. The announcement also explicitly notes that this mechanism can be used to support core functions for cohorts that are already funded through other grant mechanisms within the NCI, particularly those overseen by the Epidemiology and Genomics Research Program (EGRP) and other parts of the Division of Cancer Control and Population Sciences (DCCPS). That detail signals an intent to create consistent, sustainable infrastructure across NCI-supported cohort efforts, rather than leaving each cohort to solve the same operational problems in isolation.
Methodological research is the second major pillar of the opportunity. While the FOA text provided here does not list specific methods topics, the intent is clear: NCI is looking to fund work that improves the scientific and operational methods underpinning cohort-based cancer epidemiology. This can include innovations that make cohorts more efficient, more accurate, more harmonizable with other data resources, and better suited for long-term follow-up and analysis. In other words, the award is not only about keeping cohorts running, but also about making them better tools for answering modern questions in cancer etiology, prevention, risk prediction, disparities, and outcomes.
Administratively, this is categorized as discretionary funding and falls under an education/health activity category, with CFDA number 93.393 (Cancer Cause and Prevention Research). The FOA was posted January 29, 2015, with a closing date of March 10, 2017, and an archive date of April 10, 2017, meaning it is no longer open for applications but remains useful as a reference point for similar current NCI cohort infrastructure initiatives. The listed award ceiling is $2,500,000, which indicates the program was structured to support substantial infrastructure activities rather than small pilot projects. There is no cost sharing or matching requirement noted, which generally lowers barriers for applicants that might not have access to non-federal matching funds.
Eligibility is broad and includes many types of organizations that could host or coordinate cohort infrastructure. Eligible applicants include public entities such as state governments, county governments, city or township governments, special district governments, public housing authorities/Indian housing authorities, and independent school districts. Higher education institutions are included on both the public and private side. The FOA also allows nonprofit organizations both with and without 501(c)(3) status, as well as for-profit organizations (other than small businesses) and small businesses. Importantly, eligibility extends to tribal governments (federally recognized) and tribal organizations (non-federally recognized), along with tribally controlled colleges and universities. The additional eligibility language also includes a wide range of mission-focused or designated institutions and groups such as HBCUs, Hispanic-serving institutions, AANAPISISs, Alaska Native and Native Hawaiian-serving institutions, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, eligible federal agencies, and even non-U.S. entities (foreign organizations). Taken together, this suggests NCI wanted to encourage participation across diverse settings, including organizations that can improve representation of underserved populations or contribute unique infrastructure capabilities.
The sponsoring agency is the NIH, with NCI as the key institute behind the program. The official information page for the announcement was provided through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-15-104.html (spacing in the original source may need to be corrected when entering it into a browser). For technical issues accessing or linking to the announcement, the contact point listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is primarily for troubleshooting the posting rather than programmatic scientific questions.
Overall, this FOA reflects NCI's long-term strategy of investing in the "infrastructure layer" of cancer epidemiology: the systems, staffing, data processes, and methodological advances that allow cohorts to remain scientifically productive for years, integrate with evolving technologies and analytic approaches, and support high-impact research on cancer causes and prevention at the population level.
FAQs: Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (U01) - PAR 15 104
What is the title and funding opportunity number for this grant?
The opportunity is titled Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (U01) and the Funding Opportunity Number is PAR 15 104.
Which agency is sponsoring this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH), led by the National Cancer Institute (NCI).
What type of award mechanism is this (U01), and what does that imply?
This opportunity uses a cooperative agreement (U01) mechanism. That typically means awardees should expect an active partnership with NCI program staff, rather than a fully hands-off grant relationship.
What is the main purpose of this funding opportunity?
The central purpose is to strengthen and modernize the core infrastructure that allows Cancer Epidemiology Cohorts (CECs) to operate effectively, while also supporting methodological research that improves how cohorts are designed, maintained, and used for cancer prevention and population science.
What kinds of activities does "core infrastructure" support refer to?
Based on the description provided, core infrastructure support focuses on the foundational operational capacity that allows a cohort to generate reliable, high-value data over time. This includes targeted support for the core functions that make cohorts run effectively, emphasizing sustainable operations rather than isolated or duplicative solutions.
Does this opportunity support existing cohorts, new cohorts, or both?
It is aimed at both existing cohorts and the establishment or strengthening of new cohorts, with an emphasis on building or sustaining core operational capacity.
How does this FOA relate to other NCI-funded cohort efforts?
The announcement notes that the U01 mechanism can be used to support core functions for cohorts already funded through other NCI grant mechanisms, particularly those overseen by NCI's Epidemiology and Genomics Research Program (EGRP) and other parts of the Division of Cancer Control and Population Sciences (DCCPS). This signals an intent to promote more consistent, sustainable infrastructure across NCI-supported cohorts.
What is meant by "methodological research" in this opportunity?
Methodological research is the second major pillar of the opportunity and refers to work intended to improve the scientific and operational methods that underpin cohort-based cancer epidemiology. While specific topics are not listed in the provided text, the stated intent includes innovations that make cohorts more efficient, more accurate, more harmonizable with other data resources, and better suited for long-term follow-up and analysis.
Is this funding focused on small pilots or larger infrastructure efforts?
The listed award ceiling is $2,500,000, indicating the program was structured to support substantial infrastructure activities rather than small pilot projects.
Is cost sharing or matching required?
No cost sharing or matching requirement is noted in the information provided.
What is the CFDA number associated with this program?
The CFDA number listed is 93.393, which corresponds to Cancer Cause and Prevention Research.
How is this opportunity categorized (funding type and activity area)?
It is categorized as discretionary funding and falls under an education/health activity category.
When was the FOA posted, and what were the key dates?
The FOA was posted on January 29, 2015. The closing date was March 10, 2017, and the archive date was April 10, 2017.
Is this funding opportunity currently open for applications?
No. Based on the dates provided, it is no longer open for applications and is maintained as an archived reference.
What is the official NIH Grants Guide page for this FOA?
The official information page is listed as: http://grants.nih.gov/grants/guide/pa-files/PAR-15-104.html. (The source notes that spacing may need to be corrected when entering the URL into a browser.)
Who is eligible to apply?
Eligibility is broad and includes many organization types, including:
- Public entities (state governments, county governments, city or township governments, special district governments)
- Public housing authorities/Indian housing authorities
- Independent school districts
- Higher education institutions (public and private)
- Nonprofits (with and without 501(c)(3) status)
- For-profit organizations (other than small businesses)
- Small businesses
- Tribal governments (federally recognized)
- Tribal organizations (non-federally recognized)
- Tribally controlled colleges and universities
- U.S. territories or possessions
- Eligible federal agencies
- Non-U.S. entities (foreign organizations)
Does the FOA specifically encourage participation by certain institution types or communities?
Yes. The additional eligibility language includes a wide range of designated institutions and groups, such as HBCUs, Hispanic-serving institutions, AANAPISISs, Alaska Native and Native Hawaiian-serving institutions, as well as faith-based or community-based organizations and regional organizations. The provided description suggests an interest in broad participation, including organizations that can improve representation of underserved populations or contribute unique infrastructure capabilities.
What kinds of research goals does this infrastructure investment ultimately support?
The FOA reflects an NCI strategy of investing in the infrastructure layer that helps cohorts remain productive and adaptable over time, supporting high-impact research in areas such as cancer etiology, prevention, risk prediction, disparities, and outcomes at the population level.
Where should technical questions about accessing the posting be directed?
For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV. The description indicates this contact is primarily for troubleshooting the posting rather than programmatic scientific questions.
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| Developing Technologies and Tools to Monitor HIV Brain Reservoirs and How They May be Altered by Exposure to Substances of Abuse (R21/R33) Apply for RFA DA 15 018 Funding Number: RFA DA 15 018 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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| Gene Environment Interplay in Substance Use Disorders (R03) Apply for PA 15 111 Funding Number: PA 15 111 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Gene Environment Interplay in Substance Use Disorders (R21) Apply for PA 15 112 Funding Number: PA 15 112 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Advancing Exceptional Research on HIV/AIDS and Substance Abuse (R01) Apply for RFA DA 16 001 Funding Number: RFA DA 16 001 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NIDA Mentored Clinical Scientists Development Program Award in Drug Abuse and Addiction (K12) Apply for PAR 15 119 Funding Number: PAR 15 119 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Identification of Genetic and Genomic Variants by Next Gen in Sequencing Non human Animal Models (U01) Apply for PAR 15 120 Funding Number: PAR 15 120 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| BRAIN Initiative Optimization of Novel Tools and Technologies for Neuroscience Research (R44) Apply for PAR 15 121 Funding Number: PAR 15 121 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Functional Wellness in HIV Maximizing the Treatment Cascade (R01) Apply for PA 15 133 Funding Number: PA 15 133 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Functional Wellness in HIV Maximizing the Treatment Cascade (R21) Apply for PA 15 134 Funding Number: PA 15 134 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Administrative Supplements for Research on HIV/AIDS and Aging (Admin Supp) Apply for PA 15 137 Funding Number: PA 15 137 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
| SBIR Phase IIB Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics and Prognostics Toward Commercialization (R44) Apply for RFA CA 15 010 Funding Number: RFA CA 15 010 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
| International Research Collaboration on Drug Abuse and Addiction Research (R03) Apply for PA 15 141 Funding Number: PA 15 141 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| International Research Collaboration on Drug Abuse and Addiction Research (R01) Apply for PA 15 142 Funding Number: PA 15 142 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| International Research Collaboration on Drug Abuse and Addiction Research (R21) Apply for PA 15 143 Funding Number: PA 15 143 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Limited Competition Revisions to Add Phase 2 Clinical Trials Program to Experimental Therapeutics Clinical Trials Network (ETCTN)(UM1) Apply for RFA CA 15 501 Funding Number: RFA CA 15 501 Agency: National Institutes of Health Category: Education Health Funding Amount: $560,000 |
| Cancer Research Education Grants Program Research Experiences (R25) Apply for PAR 15 152 Funding Number: PAR 15 152 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Cancer Research Education Grants Program Courses for Skills Development (R25) Apply for PAR 15 151 Funding Number: PAR 15 151 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Cancer Research Education Grants Program Curriculum or Methods Development (R25) Apply for PAR 15 150 Funding Number: PAR 15 150 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
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