Opportunity Information: Apply for PAR 11 167
Apply for PAR 11 167
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (UM1)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.396 Cancer Biology Research 93.397 Cancer Centers Support Grants.
- This funding opportunity was created on Mar 17, 2011 and posted on Mar 17, 2011.
- Applicants must submit their applications by Nov 8, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components on applications submitted by U.S. Organizations are allowed.
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Opportunity Summary:
The Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (UM1) opportunity (Funding Opportunity Number PAR-11-167) was a National Cancer Institute (NCI) funding announcement under the National Institutes of Health (NIH) designed to strengthen the operational backbone of Cancer Epidemiology Cohorts (CECs) while also encouraging methodological research that improves how cohort-based cancer epidemiology is conducted. The central idea was to fund the shared, core functions that make large cohorts usable and scientifically productive over time, such as systems and procedures for participant follow-up, exposure and outcome data collection, biospecimen handling, data management, quality control, and governance structures that allow cohorts to function efficiently and collaborate. Importantly, the FOA allowed support for both existing cohorts and the development of new cohorts, with an emphasis on targeted infrastructure investments rather than simply funding individual, stand-alone research projects.
This was offered as a cooperative agreement (UM1), which typically means NIH staff are expected to have substantial programmatic involvement compared with a standard grant. In practice, that structure generally aligns well with infrastructure-focused awards because it supports coordination, adherence to shared standards, and the ability to integrate cohort resources with broader NCI priorities. The announcement also explicitly positioned the FOA as a way to support core functions for CECs that were already funded through other mechanisms within NCI, particularly through the Epidemiology and Genetics Program (EGRP) and other parts of the Division of Cancer Control and Population Sciences (DCCPS). In other words, this mechanism was meant to complement and sustain cohort capabilities that might otherwise be difficult to maintain under more traditional, hypothesis-driven funding structures.
The opportunity fell within NIH’s broad health and education-related funding activity categories and was tied to multiple CFDA program areas relevant to cancer research, including cancer cause and prevention, detection and diagnosis, cancer biology, and cancer centers support. While the FOA title is focused on epidemiology cohorts, the inclusion of these CFDA numbers signals that the infrastructure and methods being supported were intended to enable a wide range of cancer research questions, from identifying risk factors and etiologic pathways to improving detection strategies and supporting broader cancer research ecosystems.
Eligibility was broad and included many organizational types: public and private institutions of higher education, nonprofit organizations with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, and state governments. The FOA also listed several special categories of eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, U.S. territories or possessions, regional organizations, and eligible federal agencies. Non-U.S. entities (foreign organizations) were eligible, and foreign components were allowed on applications submitted by U.S. organizations, which is particularly relevant for cohorts that include international populations or require cross-border collaborations for follow-up, harmonization, or specialized laboratory and data resources. The FOA did not require cost sharing or matching.
Key dates reflect that this was an archived opportunity: it was posted and created on March 17, 2011, with an original and final closing date of November 8, 2013, and an archive date of December 9, 2013. The official announcement was hosted through the NIH grants guide, and the contact points provided were the NIH Office of Extramural Research (OER) webmaster emails for access or linking issues, indicating that programmatic scientific contacts would be found in the full FOA text rather than in the brief listing.
Overall, the UM1 mechanism here was aimed at keeping cancer epidemiology cohorts scientifically strong and operationally sustainable by underwriting the essential infrastructure that allows cohorts to generate reliable, shareable, and methodologically sound data over long time horizons, while also pushing forward improvements in cohort methodology. This kind of support is especially important for cohorts because their value accumulates over time, and the most critical work (consistent follow-up, standardized data and specimen processes, and well-designed data systems) is often expensive, continuous, and not easily justified as a single discrete research aim without dedicated infrastructure funding.
Frequently Asked Questions (FAQs)
What is the "Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (UM1)" opportunity?
It was a National Cancer Institute (NCI) funding announcement under the National Institutes of Health (NIH) designed to strengthen the core, shared infrastructure that keeps Cancer Epidemiology Cohorts (CECs) operational and scientifically productive over time, while also encouraging methodological research that improves how cohort-based cancer epidemiology is conducted.
What is the Funding Opportunity Number (FOA number) for this program?
The Funding Opportunity Number was PAR-11-167.
Which NIH institute offered this opportunity?
The opportunity was offered by the National Cancer Institute (NCI), a component of NIH.
What type of award mechanism did this FOA use?
This opportunity used a cooperative agreement mechanism: UM1.
What does a UM1 cooperative agreement generally imply?
A UM1 cooperative agreement typically means NIH staff are expected to have substantial programmatic involvement compared with a standard grant. In this FOA, that structure was positioned as a good fit for infrastructure-focused awards because it can support coordination, adherence to shared standards, and integration of cohort resources with broader NCI priorities.
What was the main purpose of the FOA?
The main purpose was to fund shared, core cohort functions (infrastructure) that make large cancer epidemiology cohorts usable and scientifically productive over long time horizons, and to support methodological research to improve cohort-based cancer epidemiology.
Was the FOA intended to fund individual stand-alone research projects?
The emphasis was on targeted infrastructure investments rather than simply funding individual, stand-alone research projects. The goal was to strengthen the operational backbone and methods that allow cohorts to generate reliable, high-quality data over time.
What kinds of "core functions" and infrastructure activities were highlighted?
The FOA highlighted shared functions such as participant follow-up systems and procedures, exposure and outcome data collection, biospecimen handling, data management, quality control, and governance structures that enable efficient cohort operations and collaboration.
Did this opportunity support methodological research as well as infrastructure?
Yes. In addition to funding core infrastructure, the FOA encouraged methodological research that improves how cohort-based cancer epidemiology is conducted.
Could applicants propose support for existing cohorts?
Yes. The FOA allowed support for existing Cancer Epidemiology Cohorts (CECs).
Could applicants propose developing new cohorts?
Yes. The FOA also allowed support for the development of new cohorts.
How did this FOA relate to other NCI cohort funding?
The announcement explicitly positioned this FOA as a way to support core functions for CECs that were already funded through other mechanisms within NCI, particularly through the Epidemiology and Genetics Program (EGRP) and other parts of the Division of Cancer Control and Population Sciences (DCCPS). It was described as complementary support intended to help sustain cohort capabilities that can be difficult to maintain under traditional hypothesis-driven funding structures.
What NIH activity categories did this opportunity fall under?
It fell within NIH's broad health- and education-related funding activity categories, as described in the listing.
What cancer research areas were associated with this FOA?
The listing tied the FOA to multiple CFDA program areas relevant to cancer research, including cancer cause and prevention, detection and diagnosis, cancer biology, and cancer centers support. While the FOA focused on epidemiology cohorts, those program areas signaled that the supported infrastructure and methods were intended to enable a wide range of cancer research questions.
Who was eligible to apply?
Eligibility was broad and included public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (other than small businesses); small businesses; and state governments.
Were small businesses eligible?
Yes. Small businesses were listed as eligible applicants.
Were for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) were listed as eligible, and small businesses were also listed separately as eligible.
Were nonprofit organizations required to have 501(c)(3) status?
No. The FOA included nonprofit organizations with or without 501(c)(3) status.
Were minority-serving institutions and special institutional categories eligible?
Yes. The FOA listed several special categories of eligible applicants, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, U.S. territories or possessions, regional organizations, and eligible federal agencies.
Were non-U.S. (foreign) organizations eligible to apply?
Yes. Non-U.S. entities (foreign organizations) were eligible.
Were foreign components allowed on applications from U.S. organizations?
Yes. Foreign components were allowed on applications submitted by U.S. organizations, which was noted as particularly relevant for cohorts involving international populations or cross-border collaborations (for example, follow-up, harmonization, or specialized laboratory and data resources).
Was cost sharing or matching required?
No. The FOA did not require cost sharing or matching.
Is this funding opportunity still open?
No. This was an archived opportunity.
What were the key dates for this FOA?
It was posted and created on March 17, 2011. The original and final closing date was November 8, 2013. The archive date was December 9, 2013.
Where was the official announcement hosted?
The official announcement was hosted through the NIH grants guide.
Who were the listed contacts in the brief listing?
The contact points provided were NIH Office of Extramural Research (OER) webmaster emails for access or linking issues. The listing indicated that programmatic scientific contacts would be found in the full FOA text rather than in the brief listing.
Why is infrastructure funding important for cancer epidemiology cohorts?
The FOA description emphasized that cohorts accumulate value over time, and that critical work like consistent follow-up, standardized data and specimen processes, and well-designed data systems is expensive, continuous, and not easily justified as a single discrete research aim without dedicated infrastructure support.
What was the overarching goal of using a cooperative agreement for this program?
The cooperative agreement structure was described as aligning with infrastructure-focused awards by supporting coordination, adherence to shared standards, and the ability to integrate cohort resources with broader NCI priorities.
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