Opportunity Information: Apply for RFA DP 13 003

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Cost Benefit of Incentive based Smoking Cessation for Pregnant Women" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.946 Cooperative Agreements to Support State Based Safe Motherhood and Infant Health Initiative Programs.
  • This funding opportunity was created on Dec 10, 2012 and posted on Dec 10, 2012.
  • Applicants must submit their applications by Mar 4, 2013 Letter of Intent Due Date February 4, 2013 Application Due Date March 4, 2013, by 500 PM U.S. Eastern Time. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,800,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $560,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • 1. Eligible Applicants Eligible Organizations Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Alaska Native and Native Hawaiian Serving Institutions Nonprofits Other Than Institutions of Higher Education Nonprofits (Other than Institutions of Higher Education) For Profit Organizations Small Businesses For Profit Organizations (Other than Small Businesses) Governments State Governments County Governments City or Township Governments Special District Governments Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribal Governments (Other than Federally Recognized) Eligible Agencies of the Federal Government U.S. Territory or Possession Other Independent School Districts Public Housing Authorities/Indian Housing Authorities Native American tribal organizations (other than Federally recognized tribal governments) Faith based or Community based Organizations Regional Organizations Bona Fide Agents a Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov. Federally Funded Research and Development Centers (FFRDCs) FFRDCs are operated, managed, and/or administered by a university or consortium of universities, other not for profit or nonprofit organization, or an industrial firm, as an autonomous organization or as an identifiable separate operating unit of a parent organization. A FFRDC meets some special long term research or development need which cannot be met as effectively by an agency s existing in house or contractor resources. FFRDCs enable agencies to use private sector resources to accomplish tasks that are integral to the mission and operation of the sponsoring agency. For more information on FFRDCs, go to http://ecfr.gpoaccess.gov/cgi/t/text/text idxcecfrsid512ff78311f427c00454772dcf21523argndiv8viewtextnode481.0.1.6.34.0.1.18idno48. Other None 2. Foreign Organizations Foreign Organizations are not eligible to apply. Foreign components of U.S. Organizations are not eligible to apply. For this announcement, applicants may not include collaborators or consultants from foreign institutions. All applicable federal laws and policies apply. 3. Special Eligibility Requirements Eligible applicants must have evidence of an established relationship with one or more study sites that meet the criteria
Apply for RFA DP 13 003

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Opportunity Summary:

The Centers for Disease Control and Prevention (CDC) released a discretionary funding opportunity, RFA DP 13 003, titled "Cost Benefit of Incentive based Smoking Cessation for Pregnant Women." It was offered as a cooperative agreement in the health activity category, with an estimated total program funding level of about $2.8 million and an anticipated single award. While the award ceiling is listed at $560,000 (with no stated minimum), the overall intent is to fund one recipient to carry out a rigorous evaluation focused on smoking cessation during pregnancy, with a specific emphasis on both effectiveness and economic value.

The core purpose of the announcement is to solicit proposals for a study that measures the cost benefit of an incentive-based smoking cessation intervention for pregnant smokers. The intervention model highlighted is contingency management (CM), which generally refers to providing tangible incentives when participants meet objectively verified behavior goals, such as biochemically confirmed smoking abstinence. CDC is specifically interested in comparing two different "intensity" levels of CM, which implies differences in the size, frequency, or structure of incentives and monitoring, to determine whether a higher-cost, higher-touch approach yields enough additional quit success to justify the added expense when compared with a lower-intensity version and with usual care.

The preferred study design described in the opportunity is a three-arm randomized controlled trial. The three arms are: (1) a high-intensity CM intervention during pregnancy, (2) a low-intensity CM intervention during pregnancy, and (3) a standard-of-care comparison group. The primary outcome described is smoking abstinence at the end of pregnancy, and the major analytic objective is to estimate and compare the cost benefit of the different intensity levels. In practical terms, this means applicants are expected not only to track cessation outcomes, but also to capture the resources and costs required to deliver each approach and then evaluate whether the outcomes achieved represent good value relative to the investment.

The opportunity was posted December 10, 2012. A letter of intent was due February 4, 2013, and the application due date was March 4, 2013, by 5:00 PM U.S. Eastern Time. The opportunity was later archived April 3, 2013, indicating it is no longer open, but the details still serve as a clear template of what CDC wanted to fund: a controlled, multi-arm evaluation with an economic component strong enough to inform real-world maternal and child health program decisions.

Eligibility was broad across U.S.-based organizations, including public and private institutions of higher education, nonprofits (including those outside academia), for-profit organizations (including small businesses), and multiple levels of government (state, county, city/township, special districts, territories/possessions, and tribal governments). The announcement explicitly encouraged participation from institutions that often receive targeted encouragement for federal support, such as Hispanic-serving institutions, Historically Black Colleges and Universities, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian-serving institutions. It also allowed applications from entities such as independent school districts, public housing authorities, faith-based and community-based organizations, regional organizations, bona fide agents (with required documentation from the relevant state or local government), and federally funded research and development centers (FFRDCs). At the same time, foreign organizations were not eligible, foreign components of U.S. organizations were not eligible, and applicants could not include collaborators or consultants from foreign institutions.

A key special eligibility requirement is that applicants needed evidence of an established relationship with one or more study sites that meet CDC criteria. That requirement signals that CDC expected applicants to be ready to implement and manage recruitment, intervention delivery, and follow-up in real clinical or community settings serving pregnant smokers, rather than proposing a purely conceptual or early-stage partnership. There was no cost-sharing or matching requirement, which reduces barriers for organizations that might otherwise struggle to provide non-federal funds to support the work.

In short, this CDC grant opportunity aimed to fund a single, high-quality randomized trial that directly compares high- and low-intensity incentive-based contingency management approaches against standard prenatal care, measuring both end-of-pregnancy smoking abstinence and the economic tradeoffs of each approach. The deliverable CDC was implicitly seeking is actionable evidence: whether paying for incentives and the associated program infrastructure during pregnancy is justified by improved cessation outcomes and the downstream maternal-infant health benefits those quits are expected to produce. For technical or access issues related to the full announcement, the listing provided CDC Procurement and Grants Office contact information (TIMS) at 770-488-2700 and PGOTIM@cdc.gov.

FAQs: CDC RFA DP 13 003 - Cost Benefit of Incentive-based Smoking Cessation for Pregnant Women

What is the name and identifier of this funding opportunity?

The opportunity is titled "Cost Benefit of Incentive based Smoking Cessation for Pregnant Women" and is identified as RFA DP 13 003. It was released by the Centers for Disease Control and Prevention (CDC) as a discretionary funding opportunity.

What type of award was offered?

The opportunity was offered as a cooperative agreement under the health activity category. This indicates CDC anticipated substantial involvement consistent with cooperative agreement mechanisms, based on the opportunity description.

Is this funding opportunity still open?

No. The opportunity was archived on April 3, 2013, which indicates it is no longer open for applications.

What was CDC trying to fund through this announcement?

CDC was seeking proposals to carry out a rigorous evaluation of an incentive-based smoking cessation intervention for pregnant women, with a specific emphasis on both (1) effectiveness (smoking abstinence outcomes) and (2) economic value (cost-benefit).

What intervention approach was highlighted?

The intervention model highlighted was contingency management (CM), which generally involves providing tangible incentives when participants meet objectively verified behavior goals, such as biochemically confirmed smoking abstinence.

What does "incentive-based" mean in the context of this opportunity?

In this opportunity, "incentive-based" refers to providing tangible rewards tied to meeting clearly defined, objectively verified cessation goals (for example, incentives contingent on biochemically confirmed abstinence).

What was the preferred study design?

The preferred design described was a three-arm randomized controlled trial (RCT).

What were the three study arms CDC wanted applicants to compare?

The three arms described were: (1) a high-intensity CM intervention during pregnancy, (2) a low-intensity CM intervention during pregnancy, and (3) a standard-of-care comparison group.

What does CDC mean by comparing two "intensity" levels of contingency management?

The opportunity describes interest in comparing two different CM "intensity" levels, implying differences in the size, frequency, or structure of incentives and monitoring. The goal was to test whether a higher-cost, higher-touch approach produces enough additional quitting to justify the added expense compared with a lower-intensity approach and usual care.

What was the primary outcome CDC highlighted?

The primary outcome described was smoking abstinence at the end of pregnancy.

What economic question was the study expected to answer?

The major analytic objective was to estimate and compare the cost benefit of different CM intensity levels (and to compare them with standard care). Applicants were expected to track both cessation outcomes and the resources/costs required to deliver each approach, then assess whether the outcomes represent good value relative to the investment.

How much total funding did CDC estimate for the program?

The estimated total program funding level was about $2.8 million.

How many awards did CDC anticipate making?

CDC anticipated a single award.

What was the award ceiling? Was a minimum award amount stated?

The listed award ceiling was $560,000, and no minimum award amount was stated in the information provided.

Who was eligible to apply?

Eligibility was broad across U.S.-based organizations, including public and private institutions of higher education, nonprofits (including those outside academia), for-profit organizations (including small businesses), and multiple levels of government (state, county, city/township, special districts, territories/possessions, and tribal governments).

Were any specific institution types explicitly encouraged to apply?

Yes. The announcement explicitly encouraged participation from Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), tribally controlled colleges and universities, and Alaska Native and Native Hawaiian-serving institutions.

Were community-based or faith-based organizations eligible?

Yes. The eligibility description included faith-based and community-based organizations.

Were independent school districts and public housing authorities eligible?

Yes. Independent school districts and public housing authorities were included among eligible entities.

Could federally funded research and development centers (FFRDCs) apply?

Yes. The eligibility description included federally funded research and development centers (FFRDCs).

Were foreign organizations eligible to apply?

No. Foreign organizations were not eligible.

Could a U.S. organization include a foreign component?

No. Foreign components of U.S. organizations were not eligible.

Could applicants use collaborators or consultants from foreign institutions?

No. Applicants could not include collaborators or consultants from foreign institutions.

Was there any special eligibility requirement related to study sites?

Yes. Applicants needed evidence of an established relationship with one or more study sites that met CDC criteria. This indicates CDC expected applicants to be prepared to recruit participants and deliver the intervention and follow-up in real clinical or community settings serving pregnant smokers.

Was cost sharing or matching required?

No. There was no cost-sharing or matching requirement.

What were the key dates for this opportunity?

The opportunity was posted on December 10, 2012. The letter of intent was due February 4, 2013. The application due date was March 4, 2013 by 5:00 PM U.S. Eastern Time. The opportunity was archived on April 3, 2013.

What was the overall deliverable CDC was seeking?

Based on the description, CDC was seeking actionable evidence from a controlled, multi-arm evaluation with a strong economic component. The goal was to inform real-world maternal and child health program decisions about whether paying for incentives and associated program infrastructure during pregnancy is justified by improved cessation outcomes and downstream maternal-infant health benefits.

Who should be contacted for technical or access issues related to the full announcement?

For technical or access issues, the listing provided CDC Procurement and Grants Office contact information (TIMS): 770-488-2700 and PGOTIM@cdc.gov.

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