Opportunity Information: Apply for RFA TR 15 002
Apply for RFA TR 15 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "CTSA Network Trial Innovation Centers (TICs) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.350 National Center for Advancing Translational Sciences 93.866 Aging Research.
- This funding opportunity was created on Jun 5, 2015 and posted on Jun 5, 2015.
- Applicants must submit their applications by Sep 15, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $12,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $2,400,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: County governments Others (see text field entitled Additional Information on Eligibility for clarification) State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The grant opportunity titled "CTSA Network Trial Innovation Centers (TICs) (U24)" (Funding Opportunity Number RFA-TR-15-002) is a National Institutes of Health (NIH) funding announcement issued through the National Center for Advancing Translational Sciences (NCATS). It uses a cooperative agreement mechanism (U24), which typically means the funded organizations will not only receive support but will also work in close partnership with NIH staff in carrying out the program goals. The overall intent is to build and support a small number of Trial Innovation Centers that function as national leaders in clinical trial innovation and execution, specifically to strengthen and streamline how multi-site clinical studies are carried out across the Clinical and Translational Science Award (CTSA) Program network.
At its core, this FOA is about improving the way multi-site clinical studies are implemented. The TICs are described as "lead centers of excellence" in clinical trials, with a clear operational focus: making it easier, faster, and more consistent to launch and run studies that involve more than one site. Because the CTSA Network spans many institutions, multi-site studies can get slowed down by duplicated processes, inconsistent workflows, varying contracting approaches, and uneven capacity across sites. The TIC model is meant to reduce those barriers by providing expertise, coordination, and practical support that helps studies move from planning to activation to execution more efficiently across the network.
The opportunity sits within the broad NIH health research mission and is categorized under Health as the funding activity area. It is linked to CFDA numbers 93.350 (National Center for Advancing Translational Sciences) and 93.866 (Aging Research), signaling the NCATS leadership and a connection to NIH priorities that often include aging-related research, though the primary framing is clinical trial infrastructure and innovation rather than one specific disease area. The announcement projects approximately three awards, with an estimated total funding amount of about $12,000,000. Individual awards have an annual ceiling listed at $2,400,000, indicating a substantial level of support for centers expected to operate at a national, multi-institutional scale.
Eligibility is broad and includes many types of U.S.-based entities. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) organizations as well as certain nonprofits without 501(c)(3) status, excluding institutions of higher education), for-profit organizations (including small businesses and other than small businesses), and numerous government entities such as state governments, county governments, city or township governments, special district governments, public housing authorities/Indian housing authorities, independent school districts, and tribal governments and organizations (both federally recognized and other than federally recognized, as specified). The eligibility language also explicitly includes a range of mission-focused institutional categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and certain eligible federal agencies. At the same time, the FOA draws a firm line on foreign involvement: non-U.S. (non-domestic) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components are not allowed as defined by NIH policy.
The FOA states there is no cost-sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of the award. Key dates in the public listing show it was posted and created on June 5, 2015, with an original and current closing date of September 15, 2015, and an archive date of October 16, 2015. Those dates indicate this is an archived, time-limited competition rather than an open, ongoing program announcement.
In practical terms, applicants responding to this FOA would be proposing to serve as a Trial Innovation Center that helps the CTSA Network implement multi-site clinical studies more effectively. While the listing summary does not spell out specific required cores or workstreams, the stated purpose strongly implies responsibilities like providing clinical trial operations expertise, improving start-up and site activation processes, supporting consistent study implementation across institutions, and serving as a central resource to help studies run smoothly across multiple CTSA sites. Because the mechanism is a cooperative agreement, awardees should also expect substantial NIH involvement in governance, coordination, performance expectations, and alignment with network-wide priorities.
For further detail, the full announcement was hosted by NIH at the link provided in the listing (http://grants.nih.gov/grants/guide/rfa-files/RFA-TR-15-002.html). The contact information in the listing directs technical access or linking issues to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, reflecting that this posting was also distributed through federal opportunity listing systems.
FAQs: CTSA Network Trial Innovation Centers (TICs) (U24) - RFA-TR-15-002
What is the title of this grant opportunity?
The opportunity is titled "CTSA Network Trial Innovation Centers (TICs) (U24)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA-TR-15-002.
Which federal agency is offering this funding?
This is a National Institutes of Health (NIH) funding announcement.
Which NIH center is issuing the announcement?
The announcement is issued through the National Center for Advancing Translational Sciences (NCATS).
What type of funding mechanism is used?
The mechanism is a cooperative agreement (U24).
What does a U24 cooperative agreement generally imply for awardees?
It typically means funded organizations receive support while working in close partnership with NIH staff to carry out program goals, with substantial NIH involvement in coordination, governance, and alignment with network-wide priorities.
What is the overall purpose of the Trial Innovation Centers (TICs)?
The intent is to build and support a small number of TICs that serve as national leaders in clinical trial innovation and execution, strengthening and streamlining how multi-site clinical studies are carried out across the CTSA Program network.
What kind of studies are TICs intended to support?
The focus is on multi-site clinical studies, especially those conducted across the CTSA network.
Why are TICs needed within the CTSA Network?
Multi-site studies can be slowed by duplicated processes, inconsistent workflows, varying contracting approaches, and uneven capacity across sites. The TIC model aims to reduce these barriers by providing expertise, coordination, and practical support.
How are TICs described in the announcement summary?
TICs are described as "lead centers of excellence" in clinical trials with an operational focus on making it easier, faster, and more consistent to launch and run multi-site studies.
What is the funding activity area for this opportunity?
The funding activity area is Health.
Which CFDA numbers are associated with this opportunity?
The listing is linked to CFDA 93.350 (National Center for Advancing Translational Sciences) and 93.866 (Aging Research).
Does this FOA focus on a specific disease area?
Based on the provided summary, it is framed primarily around clinical trial infrastructure and innovation rather than a single disease area, though one associated CFDA number reflects aging research priorities.
How many awards were anticipated?
The announcement projected approximately three awards.
What was the estimated total funding amount?
The estimated total funding amount was about $12,000,000.
Is there an annual budget ceiling per award?
Yes. Individual awards have an annual ceiling listed at $2,400,000.
Is cost sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad for U.S.-based entities and includes public and private institutions of higher education; nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status, excluding institutions of higher education); for-profit organizations (including small businesses and other than small businesses); and many government entities (state, county, city or township, special district governments, public housing authorities/Indian housing authorities, independent school districts), as well as tribal governments and organizations (federally recognized and other than federally recognized, as specified).
Are specific institution types explicitly included as eligible?
Yes. The eligibility language explicitly includes HBCUs, Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs, as well as faith-based or community-based organizations and certain eligible federal agencies.
Are foreign (non-U.S.) organizations eligible to apply?
No. Non-U.S. (non-domestic) entities and foreign institutions are not eligible to apply.
Can a U.S. organization include a non-domestic component?
No. Non-domestic components of U.S. organizations are not eligible.
Are foreign components allowed under NIH policy for this opportunity?
No. Foreign components are not allowed as defined by NIH policy.
What timeframe did this competition operate under?
The listing shows it was posted/created on June 5, 2015, had an original and current closing date of September 15, 2015, and an archive date of October 16, 2015.
Is this funding opportunity currently open?
No. Based on the provided dates and archive status, it is an archived, time-limited competition rather than an open, ongoing program announcement.
What kinds of responsibilities would an applicant propose under this FOA?
Based on the stated purpose, applicants would propose to function as a Trial Innovation Center helping the CTSA Network implement multi-site clinical studies more effectively, including providing clinical trial operations expertise, improving study start-up and site activation processes, supporting consistent implementation across institutions, and serving as a central resource to help studies run smoothly across multiple CTSA sites.
Does the summary list specific required cores, components, or workstreams?
No. The provided listing summary does not spell out specific required cores or workstreams, but it emphasizes improving and streamlining multi-site trial implementation across the network.
Where can the full FOA text be found?
The full announcement was hosted by NIH at: http://grants.nih.gov/grants/guide/rfa-files/RFA-TR-15-002.html
Who is listed as a contact for technical access or linking issues?
The listing directs technical access or linking issues to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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