Opportunity Information: Apply for PAR 15 079
Apply for PAR 15 079
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Cutting Edge Basic Research Awards (CEBRA) (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Jan 8, 2015 and posted on Jan 8, 2015.
- Applicants must submit their applications by Dec 20, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $125,000.00 in funding.
- Eligible applicants include: City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Small businesses State governments County governments Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Cutting Edge Basic Research Awards (CEBRA) (R21) program is a National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) grant opportunity intended to push addiction science into new territory by funding ideas that are genuinely unconventional, early-stage, and potentially transformative. The core purpose is to encourage basic research on drug abuse and addiction, including how to prevent and treat substance use disorders, when the approach is high risk but could yield high impact. In practice, this program is aimed at work that is not well represented in NIDA's existing research portfolio and might otherwise struggle to get supported because it is too speculative, too novel, or too methodologically untested for more traditional funding mechanisms.
CEBRA emphasizes two main kinds of projects. First, it supports research that tests a highly novel and significant hypothesis where there is little prior work and limited preliminary data. The idea is that, even if the evidence base is still thin, the hypothesis should be bold and important enough that confirming it would meaningfully change how the field thinks about addiction mechanisms, trajectories, or intervention targets. Second, it supports projects focused on developing, adapting, or applying innovative techniques and methods for addiction research, especially methods that could open up new lines of investigation or substantially improve what researchers can measure, model, or manipulate in drug abuse research in the future. This could include emerging tools, cross-disciplinary approaches, or creative methodological shifts that are not yet widely adopted in addiction science.
The funding instrument is an NIH grant under the R21 activity code, which is commonly used for exploratory or developmental projects that are earlier-stage and geared toward innovation rather than extensive preliminary validation. The opportunity is listed as discretionary funding, and it falls within the health and education-related funding activity area tied to CFDA number 93.279 (Drug Abuse and Addiction Research Programs). The opportunity does not require cost sharing or matching, meaning applicants are not expected to contribute a required portion of funds to receive an award.
The posted opportunity (Funding Opportunity Number PAR-15-079) originally opened on January 8, 2015, with a closing date of December 20, 2017, and it was archived on January 20, 2018. The listed award ceiling is $125,000, which signals a relatively small, targeted budget consistent with exploratory, proof-of-concept, or method-development work rather than large-scale clinical trials or long multi-site studies.
Eligibility is broad and includes many types of organizations that might be positioned to do innovative addiction-related research. Eligible applicants include public and private institutions of higher education, state and local governments (state, county, city/township, special districts), independent school districts, small businesses, and for-profit organizations other than small businesses. The opportunity also includes nonprofit organizations both with and without 501(c)(3) status (other than institutions of higher education), public housing authorities, and a wide range of tribal entities, including federally recognized tribal governments and other tribal organizations. Additional eligible categories include U.S. territories or possessions, regional organizations, faith-based or community-based organizations, and a variety of minority-serving institutions such as HBCUs, Hispanic-serving institutions, AANAPISIs, tribal colleges and universities, and Alaska Native and Native Hawaiian-serving institutions. Notably, non-U.S. entities (foreign organizations) are also listed among the eligible applicants, indicating that NIDA was open to supporting certain international applicants under the terms of the announcement.
For applicants seeking the official program requirements and application instructions, the additional information link points to the NIH grants guide page for PAR-15-079. For technical issues accessing the announcement or linking problems, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@od.nih.gov.
Cutting Edge Basic Research Awards (CEBRA) (R21) - FAQs
What is the Cutting Edge Basic Research Awards (CEBRA) (R21) program?
CEBRA is a National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) grant opportunity designed to push addiction science into new territory by supporting ideas that are genuinely unconventional, early-stage, and potentially transformative.
What is the main purpose of this funding opportunity?
The core purpose is to encourage basic research on drug abuse and addiction, including research relevant to preventing and treating substance use disorders, specifically when the approach is high risk but could yield high impact.
What kinds of projects is CEBRA meant to support?
CEBRA is meant to support work that is not well represented in NIDA's existing research portfolio and may have trouble being funded through more traditional mechanisms because it is too speculative, too novel, or relies on methods that are not yet well tested.
What are the two main project types emphasized by CEBRA?
CEBRA emphasizes (1) projects that test a highly novel and significant hypothesis with little prior work and limited preliminary data, and (2) projects that develop, adapt, or apply innovative techniques and methods for addiction research that can open new lines of investigation or substantially improve research capabilities.
Does CEBRA require extensive preliminary data?
No. A key emphasis is on bold, important hypotheses where there is limited preliminary data and little prior work, as long as the idea is genuinely novel and potentially field-changing.
What does "high risk, high impact" mean in the context of this program?
It refers to research that may be more speculative or unproven than typical proposals (higher risk), but where success could meaningfully change how the field understands addiction mechanisms, trajectories, or intervention targets (high impact).
What is the funding mechanism or activity code for this program?
The funding instrument is an NIH grant under the R21 activity code, which is commonly used for exploratory or developmental projects that are earlier-stage and geared toward innovation rather than extensive preliminary validation.
Is this opportunity discretionary funding?
Yes. The opportunity is listed as discretionary funding.
What is the CFDA number associated with this opportunity?
The opportunity falls within CFDA 93.279 (Drug Abuse and Addiction Research Programs).
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
What is the award ceiling for this funding opportunity?
The listed award ceiling is $125,000, indicating a relatively small, targeted budget consistent with exploratory, proof-of-concept, or method-development projects rather than large-scale studies.
When did this funding opportunity open and close?
The posted opportunity (Funding Opportunity Number PAR-15-079) opened on January 8, 2015, and had a closing date of December 20, 2017.
Is this funding opportunity still active?
No. It was archived on January 20, 2018.
What is the Funding Opportunity Number (FON) for this program?
The Funding Opportunity Number is PAR-15-079.
What types of organizations are eligible to apply?
Eligibility is broad. Eligible applicants include public and private institutions of higher education; state and local governments (including counties, cities/townships, and special districts); independent school districts; small businesses; for-profit organizations other than small businesses; nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education); public housing authorities; and regional organizations.
Are tribal entities eligible?
Yes. The eligible categories include federally recognized tribal governments and other tribal organizations.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are listed among eligible applicants.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are included among eligible applicants.
Are minority-serving institutions included in eligibility?
Yes. Eligibility includes a range of minority-serving institutions such as HBCUs, Hispanic-serving institutions, AANAPISIs, tribal colleges and universities, and Alaska Native and Native Hawaiian-serving institutions.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. Non-U.S. entities (foreign organizations) are listed among eligible applicants, indicating that international applicants could be supported under the terms of the announcement.
Where can applicants find the official requirements and application instructions?
The additional information link points to the NIH Grants Guide page for PAR-15-079, which contains the official program requirements and application instructions.
Who should be contacted for technical issues with accessing the announcement?
For technical issues accessing the announcement or linking problems, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@od.nih.gov.
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