Opportunity Information: Apply for PAR 06 209
Apply for PAR 06 209
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Cutting Edge Basic Research Awards (CEBRA) (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 5, 2008 and posted on Mar 8, 2006.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $100,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) City or township governments County governments Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education State governments Independent school districts For profit organizations other than small businesses.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government are eligible to apply.
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Opportunity Summary:
The Cutting Edge Basic Research Awards (CEBRA) (R21) funding opportunity (PAR 06-209) is a National Institutes of Health (NIH) program administered through the National Institute on Drug Abuse (NIDA) that focuses on pushing early-stage, unconventional basic research in drug abuse and addiction. The core purpose is to encourage ideas that are genuinely innovative or conceptually creative, especially projects that are high-risk but could produce high-impact advances if they work. In practice, this means NIDA is looking for research that challenges existing assumptions, explores new mechanisms or models, or opens up entirely new lines of inquiry that could ultimately improve prevention and treatment approaches. A key feature of the opportunity is its explicit interest in areas that are underrepresented or not currently included in NIDA's existing research portfolio, making it a fit for investigators proposing less traditional approaches that still connect clearly to substance use disorders and addiction science.
This opportunity is offered as a grant using the NIH R21 activity code, which is generally associated with exploratory and developmental research. The R21 structure is commonly used to support early proof-of-concept work, preliminary testing of bold hypotheses, development of novel tools or methods, or other foundational studies that may not yet have extensive preliminary data. The announcement is categorized as discretionary funding and falls under education and health-related funding activity. The relevant CFDA listing is 93.279, Drug Abuse and Addiction Research Programs, which signals that applications should align with the broad mission of improving understanding of drug abuse and addiction and informing strategies to prevent or treat these conditions.
In terms of award size, the listed award ceiling is $100,000. The opportunity does not require cost sharing or matching, which reduces the financial burden on applicants and can make it easier for smaller organizations or newer research programs to compete. The funding announcement indicates multiple receipt dates rather than a single deadline, meaning applications were accepted on an ongoing schedule tied to NIH receipt cycles (with the specific dates and instructions provided in the full announcement). Administratively, the opportunity was posted on March 8, 2006, and later archived on June 1, 2009, so it is best treated as a historical announcement unless it has been reissued under a newer program number or replaced by a current NIDA R21 initiative.
Eligibility is broad and includes many types of domestic U.S. organizations as well as foreign institutions and eligible U.S. federal agencies. Eligible applicants include nonprofit organizations (both with and without 501(c)(3) status), public and private institutions of higher education, for-profit organizations other than small businesses, state governments, county and city/township governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, and Native American tribal governments (both federally recognized and other tribal organizations). The inclusion of foreign institutions is notable because it allows international research organizations to apply directly, which can be important for global or cross-cultural addiction research, unique datasets, or specialized scientific capabilities located outside the United States.
For anyone who needs the complete requirements, application instructions, and detailed scientific scope, the full announcement was hosted on the NIH Grants Guide website (linked in the source as http://grants.nih.gov/grants/guide/pa-files/PAR-06-209.html). The provided support contact for technical access or linking issues is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Cutting Edge Basic Research Awards (CEBRA) (R21) - PAR 06-209: FAQs
What is the Cutting Edge Basic Research Awards (CEBRA) (R21) opportunity?
CEBRA (R21) is a National Institutes of Health (NIH) funding opportunity administered through the National Institute on Drug Abuse (NIDA). It is designed to support early-stage, unconventional basic research related to drug abuse and addiction.
What is the main goal of this program?
The core purpose is to encourage genuinely innovative or conceptually creative research ideas, especially projects that are high-risk but could lead to high-impact advances if successful. The program emphasizes bold, early basic research that could open new directions for prevention and treatment in the future.
What type of research does NIDA want to support through this opportunity?
This opportunity focuses on early-stage, unconventional basic research in drug abuse and addiction. It favors work that challenges existing assumptions, explores new mechanisms or models, or opens new lines of scientific inquiry that could ultimately improve prevention or treatment approaches.
Does the program prioritize any particular research niches or gaps?
Yes. A key feature is explicit interest in areas that are underrepresented or not currently included in NIDA's existing research portfolio. That makes it particularly relevant for investigators proposing less traditional approaches, as long as the work connects clearly to substance use disorders and addiction science.
What grant mechanism is used for this opportunity?
The opportunity uses the NIH R21 activity code, which is typically used for exploratory and developmental research.
What kinds of projects are a good fit for an NIH R21 in this context?
Based on the description, this R21 is intended to support exploratory work such as early proof-of-concept studies, preliminary testing of bold hypotheses, development of novel tools or methods, and other foundational studies that may not yet have extensive preliminary data.
What is the CFDA number associated with this funding opportunity?
The relevant CFDA listing is 93.279, Drug Abuse and Addiction Research Programs.
How much funding is available per award?
The listed award ceiling is $100,000.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
Is this opportunity considered discretionary funding?
Yes. The announcement is categorized as discretionary funding and falls under education and health-related funding activity.
When was this funding opportunity posted, and is it still active?
The opportunity was posted on March 8, 2006, and it was archived on June 1, 2009. Based on that information, it should be treated as a historical announcement unless it has been reissued under a newer program number or replaced by a current NIDA R21 initiative.
Were applications accepted on a single deadline or multiple dates?
The funding announcement indicates multiple receipt dates rather than a single deadline, meaning applications were accepted on an ongoing schedule tied to NIH receipt cycles (with specific dates and instructions provided in the full announcement).
Who is eligible to apply?
Eligibility is broad. Eligible applicants include many types of domestic U.S. organizations, foreign institutions, and eligible U.S. federal agencies.
Are nonprofits eligible, including those without 501(c)(3) status?
Yes. Eligible applicants include nonprofit organizations with 501(c)(3) status and nonprofit organizations without 501(c)(3) status.
Are universities and colleges eligible?
Yes. Public and private institutions of higher education are eligible.
Are for-profit organizations eligible?
Yes. For-profit organizations other than small businesses are listed as eligible applicants.
Are state and local governments eligible?
Yes. Eligibility includes state governments, county governments, and city/township governments.
Are school districts eligible?
Yes. Independent school districts are included among eligible applicants.
Are special district governments eligible?
Yes. Special district governments are listed as eligible applicants.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are included among eligible applicants.
Are Native American tribal governments and tribal organizations eligible?
Yes. Native American tribal governments (federally recognized) and Native American tribal organizations (other than federally recognized tribal governments) are both included as eligible applicants.
Are foreign institutions eligible to apply directly?
Yes. The inclusion of foreign institutions is specifically noted, allowing international research organizations to apply directly. This can be relevant for global or cross-cultural addiction research, unique datasets, or specialized scientific capabilities outside the United States.
Where can applicants find the full announcement and complete requirements?
The full announcement was hosted on the NIH Grants Guide website at: http://grants.nih.gov/grants/guide/pa-files/PAR-06-209.html.
Who should be contacted for technical access or linking issues related to the announcement?
The provided support contact for technical access or linking issues is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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Applicants who have applied for this opportunity (PAR 06 209) also looked into and applied for these:
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| The Development of Frontal Cortex and Limbic System and their roles in Drug Abuse or Mental Health (R21) Apply for PA 06 445 Funding Number: PA 06 445 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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| Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R03) Apply for PA 06 497 Funding Number: PA 06 497 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis(R21) Apply for PA 06 499 Funding Number: PA 06 499 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Pathophysiology of Bisphosphonates associated Osteonecrosis of the Jaw (R03) Apply for PA 06 502 Funding Number: PA 06 502 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
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