Opportunity Information: Apply for RFA DK 09 009

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Cystic Fibrosis Research and Translation Core Centers (P30)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Jul 23, 2009 and posted on Jul 23, 2009.
  • Applicants must submit their applications by Nov 17, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,700,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $750,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Independent school districts For profit organizations other than small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Special district governments City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education County governments Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Cystic Fibrosis Research and Translation Core Centers (P30) funding opportunity (RFA-DK-09-009) is a National Institutes of Health program run through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that aims to strengthen and accelerate cystic fibrosis (CF) research by supporting centralized, shared research infrastructure at eligible institutions. The main idea is to fund “core centers” that bring together established CF investigators and provide them with shared resources, services, and expertise that individual labs or clinical groups might not be able to sustain efficiently on their own. By doing that, the program is meant to speed progress from basic discoveries to practical clinical advances, particularly the development and testing of new therapies for CF.

This opportunity uses the NIH P30 mechanism, which is specifically designed for “core center” support rather than funding a single research project. In practice, that means the grant is focused on building and operating shared cores (for example, specialized scientific, clinical, or technical services) that multiple CF-related projects can use. The centers are expected to support both basic and clinical CF research and to serve as a hub for collaboration, coordination, and translation. A major emphasis is on leveraging a strong existing CF research base at the applicant institution(s), then enhancing productivity and cross-disciplinary teamwork by making high-value shared resources broadly available to investigators working on CF.

Another central feature is support for pilot and feasibility studies. These are typically smaller, early-stage projects intended to help investigators generate preliminary data, test a new approach, or explore a novel therapeutic direction that could later grow into larger standalone research grants. Including pilot and feasibility work signals that NIDDK wanted these centers not only to provide routine infrastructure, but also to actively stimulate innovation, bring new investigators or new ideas into the CF space, and help launch promising translational paths toward therapies.

For funding, NIDDK anticipated a total of $2.7 million in awards in fiscal year 2010 and expected to make about three awards under this announcement. The listed award ceiling was $750,000. There was no cost sharing or matching requirement. The opportunity was posted July 23, 2009, with an application deadline of November 17, 2009, and it was later archived on December 18, 2009.

Eligibility was broad and included many types of U.S.-based entities, reflecting NIH’s general approach to allowing diverse institutions to compete when they have the needed scientific capacity. Eligible applicants included public and private institutions of higher education, nonprofit and for-profit organizations (with the exception of small business being separately listed), state and local governments, independent school districts, public housing authorities/Indian housing authorities, tribal governments and tribal organizations, special district governments, and U.S. territories or possessions. The announcement also explicitly referenced eligibility for organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and certain federal agencies and regional organizations, as described in the full eligibility text.

Overall, this FOA was designed to create or strengthen CF research and translation “centers of gravity” where shared cores, coordinated collaborations, and targeted pilot funding could collectively shorten the path from lab insights to clinical testing and, ultimately, to better treatments for people living with cystic fibrosis. For full details, NIH directed applicants to the official announcement page and provided NIH Office of Extramural Research (OER) contacts for access or linking issues.

Frequently Asked Questions (FAQs): Cystic Fibrosis Research and Translation Core Centers (P30) - RFA-DK-09-009

What is the Cystic Fibrosis Research and Translation Core Centers (P30) opportunity?

This funding opportunity (RFA-DK-09-009) is an NIH program administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Its purpose is to strengthen and accelerate cystic fibrosis (CF) research by supporting centralized, shared research infrastructure at eligible institutions through the NIH P30 "core center" mechanism.

What is the main goal of this program?

The program is meant to speed progress in cystic fibrosis research by funding "core centers" that unite established CF investigators and provide shared resources, services, and expertise. By supporting centralized infrastructure that multiple investigators can use, the centers are intended to improve collaboration and help move basic discoveries toward clinical advances, including the development and testing of new CF therapies.

Which NIH institute runs this program?

The program is run through NIDDK (the National Institute of Diabetes and Digestive and Kidney Diseases), which is part of the National Institutes of Health (NIH).

What does the NIH P30 mechanism support?

The P30 mechanism is designed for "core center" support rather than funding a single research project. In practice, this means the grant is focused on building and operating shared cores (specialized scientific, clinical, or technical services) that can be used by multiple CF-related projects and investigators.

Is this grant meant to fund one specific research project?

No. Based on the P30 mechanism description in the opportunity, the emphasis is on shared infrastructure (cores) and coordinated center activities, not on a single standalone research project.

What types of activities or resources are these core centers expected to provide?

The centers are expected to provide centralized, shared resources, services, and expertise that individual labs or clinical groups might not be able to sustain efficiently on their own. These shared cores may include specialized scientific, clinical, or technical services that support both basic and clinical CF research and facilitate collaboration and translation.

Does the program support both basic and clinical cystic fibrosis research?

Yes. The centers are expected to support both basic and clinical CF research and serve as a hub for collaboration, coordination, and translation.

How does this opportunity encourage translation to therapies?

The program is described as having a strong emphasis on speeding progress from basic discoveries to practical clinical advances, particularly the development and testing of new therapies. The structure of shared cores, coordinated collaboration, and pilot/feasibility work is meant to shorten the path from lab insights to clinical testing.

What are pilot and feasibility studies in the context of this program?

Pilot and feasibility studies are smaller, early-stage projects supported by the center. They are intended to help investigators generate preliminary data, test a new approach, or explore a novel therapeutic direction that could later develop into larger standalone research grants.

Why are pilot and feasibility studies included?

Including pilot and feasibility support signals that the centers are expected not only to provide routine infrastructure, but also to stimulate innovation, bring in new investigators or new ideas, and help launch promising translational paths toward therapies.

How much funding did NIDDK anticipate awarding under this announcement?

NIDDK anticipated a total of $2.7 million in awards in fiscal year 2010 under this funding opportunity.

How many awards were expected?

The announcement indicated that NIDDK expected to make about three awards.

What was the maximum award amount (award ceiling)?

The listed award ceiling was $750,000.

Was there a cost sharing or matching requirement?

No. The opportunity stated there was no cost sharing or matching requirement.

When was this opportunity posted and when was the application deadline?

The opportunity was posted on July 23, 2009, and the application deadline was November 17, 2009.

Is this funding opportunity still active?

No. The announcement was later archived on December 18, 2009.

Who was eligible to apply?

Eligibility was broad and included many types of U.S.-based entities. Eligible applicants included public and private institutions of higher education, nonprofit and for-profit organizations (with small business referenced separately), state and local governments, independent school districts, public housing authorities/Indian housing authorities, tribal governments and tribal organizations, special district governments, and U.S. territories or possessions.

Did the eligibility language mention specific institution categories such as HBCUs or Hispanic-serving institutions?

Yes. The eligibility description explicitly referenced organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and certain federal agencies and regional organizations, as described in the full eligibility text.

What is the program trying to build at eligible institutions?

The program is designed to create or strengthen CF research and translation "centers of gravity" that coordinate collaborations, operate shared cores, and support targeted pilot funding to accelerate progress toward better treatments.

What did NIH indicate for obtaining full details or help with access/linking issues?

For full details, NIH directed applicants to the official announcement page and provided NIH Office of Extramural Research (OER) contacts for access or linking issues.

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