Opportunity Information: Apply for RFA DD 12 001

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Data Coordinating Center for Autism and Other Developmental Disabilities Research and Epidemiologic Studies (U10)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance.
  • This funding opportunity was created on Nov 14, 2011 and posted on Nov 14, 2011.
  • Applicants must submit their applications by Jan 13, 2012 On time submission requires that electronic applications be error free and made available to CDC for processing from eRA Commons on or before the deadline date. Applications must be submitted to and validated successfully by Grants.gov/eRA Commons no later than 500 PM U.S. Eastern Time. Note HHS/CDC grant submission procedures do not provide a period of time beyond the application due date to correct any error or warning notices of noncompliance with application instructions that are identified by Grants.gov or eRA systems (i.e., error correction window).. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,600,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $900,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for RFA DD 12 001

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Opportunity Summary:

This funding opportunity, RFA DD 12 001, is a CDC cooperative agreement (U10) focused on creating and operating a single Data Coordinating Center (DCC) to support the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) network. The central aim is not to run a new autism study from scratch, but to coordinate, standardize, manage, and safeguard the large volume of data produced by CADDRE sites, with particular emphasis on the multi-site Study to Explore Early Development (SEED) phases I and II (originally funded under FOA DD11 002). In practical terms, the DCC is expected to serve as the hub that makes multi-site epidemiologic research function smoothly by ensuring data are comparable across locations, properly documented, high-quality, and usable for timely analysis.

The core purpose of the DCC is to enable SEED and other CADDRE investigators to conduct rigorous analyses that strengthen scientific understanding of Autism Spectrum Disorders (ASD) and related developmental disabilities, and to translate those findings into evidence that can inform public health decisions. Because SEED is a complex, multi-site effort, the coordinating center role is typically understood to include responsibilities such as developing and maintaining data systems; creating common data dictionaries and standards; overseeing data cleaning, validation, and quality assurance; managing secure data transfers; supporting harmonization of measures across sites; tracking study progress and data completeness; and preparing analysis-ready datasets and documentation so investigators can answer research questions efficiently and consistently.

Administratively, this is a discretionary health grant administered by the Centers for Disease Control and Prevention under CFDA 93.283 (CDC Investigations and Technical Assistance). It is issued as a cooperative agreement, meaning CDC likely anticipates substantial programmatic involvement during the period of performance, such as collaboration on deliverables, milestones, data management expectations, and coordination needs across the CADDRE network. The announcement anticipated a single award (ExpectedAwards: 1), reinforcing that the intent was to fund one central coordinating entity rather than multiple regional or competing centers.

The total estimated funding listed is $3.6 million, with an award ceiling of $900,000 (and an award floor of $0), implying the maximum annual budget or maximum per budget period listed in the announcement is $900,000, with total projected support across the full project period summing to about $3.6 million. Cost sharing or matching was not required. Eligibility is described as unrestricted, meaning a wide range of organizations could apply (for example, universities, nonprofits, for-profits, and governmental entities), subject to any additional clarifications in the full announcement.

Key timing and submission rules were strict. The opportunity was posted November 14, 2011, and closed January 13, 2012 (5:00 PM U.S. Eastern Time). The notice emphasizes that applications had to be error-free and fully validated in Grants.gov and eRA Commons by the deadline. Importantly, CDC/HHS procedures for this announcement did not allow an error-correction window after the due date, so technical submission errors discovered at or after the deadline could result in the application not being accepted for review. The opportunity was archived February 12, 2012.

For applicants that period, the main takeaway is that CDC was looking for an organization with strong, demonstrated capacity in large-scale epidemiologic data coordination, secure data infrastructure, multi-site study support, and the collaborative skills needed to serve a network of investigators. The deliverable is essentially the data backbone for SEED and related CADDRE work, designed to maximize the scientific value of the collected information and improve the ability of researchers and public health leaders to understand ASD and related developmental disabilities in ways that can guide real-world public health action. For access issues related to the full announcement, the listed point of contact was the CDC Procurement and Grants Office Technical and Information Management Section (TIMS) at 770-488-2700 for general submission inquiries.

Frequently Asked Questions (FAQs)

1. What is RFA DD 12 001?

RFA DD 12 001 is a Centers for Disease Control and Prevention (CDC) funding opportunity for a cooperative agreement (U10) to create and operate a single Data Coordinating Center (DCC) supporting the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) network.

2. What is being funded under this opportunity?

The opportunity funds one central Data Coordinating Center (DCC). The DCC is intended to coordinate, standardize, manage, and safeguard data produced by CADDRE sites, with particular emphasis on the multi-site Study to Explore Early Development (SEED) phases I and II.

3. Is this funding meant to start a new autism study?

No. The central aim is not to run a new autism study from scratch. The focus is on coordinating and supporting multi-site data activities so that SEED and other CADDRE work can be analyzed efficiently and consistently.

4. What is the CADDRE network?

CADDRE stands for the Centers for Autism and Developmental Disabilities Research and Epidemiology network. In this opportunity, CADDRE sites are generating data that the DCC would coordinate and manage to support network-wide epidemiologic research.

5. What is SEED, and why is it emphasized?

SEED is the Study to Explore Early Development, described as a complex, multi-site effort. This opportunity places particular emphasis on SEED phases I and II, which were originally funded under FOA DD11 002.

6. What is the main purpose of the Data Coordinating Center (DCC)?

The DCC is intended to serve as the hub that enables multi-site epidemiologic research to function smoothly by making sure data are comparable across locations, properly documented, high-quality, and usable for timely analysis by investigators.

7. What kinds of activities would a DCC typically be responsible for?

Based on the description provided, typical responsibilities include:

  • Developing and maintaining data systems
  • Creating common data dictionaries and data standards
  • Overseeing data cleaning, validation, and quality assurance
  • Managing secure data transfers
  • Supporting harmonization of measures across multiple sites
  • Tracking study progress and data completeness
  • Preparing analysis-ready datasets and related documentation

8. What is the expected impact of the DCC on autism and developmental disabilities research?

The DCC is intended to enable rigorous analyses that strengthen scientific understanding of Autism Spectrum Disorders (ASD) and related developmental disabilities, and to help translate findings into evidence that can inform public health decisions.

9. What type of funding mechanism is this?

This opportunity is a CDC cooperative agreement (U10). The cooperative agreement structure indicates CDC likely anticipated substantial programmatic involvement during the project, such as collaboration on deliverables, milestones, data management expectations, and coordination across the CADDRE network.

10. What agency is administering the award?

The award is administered by the Centers for Disease Control and Prevention (CDC).

11. What is the CFDA number associated with this opportunity?

The CFDA listed is 93.283, described as "CDC Investigations and Technical Assistance."

12. How many awards were expected?

The announcement anticipated a single award (ExpectedAwards: 1), meaning the intent was to fund one central coordinating entity rather than multiple centers.

13. How much total funding was estimated for this opportunity?

The total estimated funding listed is $3.6 million.

14. What is the maximum award amount?

The award ceiling is listed as $900,000. The announcement also lists an award floor of $0.

15. Does the opportunity require cost sharing or matching?

No. Cost sharing or matching was not required.

16. Who was eligible to apply?

Eligibility is described as unrestricted, meaning a wide range of organizations could apply, such as universities, nonprofits, for-profits, and governmental entities, subject to any additional clarifications in the full announcement.

17. When was the opportunity posted and when did it close?

The opportunity was posted on November 14, 2011 and closed on January 13, 2012 at 5:00 PM U.S. Eastern Time.

18. Were there special submission requirements related to Grants.gov and eRA Commons?

Yes. The notice emphasized that applications had to be error-free and fully validated in Grants.gov and eRA Commons by the deadline.

19. Was there an error-correction window after the deadline?

No. CDC/HHS procedures for this announcement did not allow an error-correction window after the due date. Technical submission errors discovered at or after the deadline could result in the application not being accepted for review.

20. When was the opportunity archived?

The opportunity was archived on February 12, 2012.

21. What capabilities was CDC looking for in an applicant?

Based on the description provided, CDC was looking for an organization with strong capacity in large-scale epidemiologic data coordination, secure data infrastructure, multi-site study support, and the collaborative skills needed to serve a network of investigators.

22. What is the main deliverable funded by this award?

The deliverable is essentially the data backbone for SEED and related CADDRE work, designed to maximize the scientific value of collected information and improve the ability of researchers and public health leaders to use findings to guide public health action.

23. Who was listed as the point of contact for access or submission issues?

For access issues related to the full announcement and general submission inquiries, the listed point of contact was the CDC Procurement and Grants Office Technical and Information Management Section (TIMS) at 770-488-2700.

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