Opportunity Information: Apply for RFA RM 16 021
Apply for RFA RM 16 021
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Data in the Context of Comparable Gene, Protein, and Lipid Data (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310.
- This funding opportunity was created on Sep 16, 2016.
- Applicants must submit their applications by Nov 28, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
This funding opportunity, titled "Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Data in the Context of Comparable Gene, Protein, and Lipid Data (U01)," is a National Institutes of Health (NIH) cooperative agreement aimed at building practical, easy-to-use resources that help researchers work with carbohydrate-related data in the same streamlined way they already handle gene, protein, and lipid information. It sits within the NIH Common Fund program area called Accelerating Translation of Glycoscience Integration and Accessibility, which focuses on lowering the barriers to studying glycans (carbohydrates) and glycoconjugates so that scientists outside of traditional glycoscience labs can incorporate these molecules into mainstream biomedical research.
At its core, the opportunity addresses a long-standing gap: carbohydrate and glycoconjugate biology is critically important to health and disease, but the data, analytical approaches, and informatics infrastructure have historically been harder to access and harder to integrate with the more standardized ecosystems built around genomics, proteomics, and lipidomics. The grant’s emphasis on "data integration and analysis tools" signals a strong informatics and usability focus. The intent is to support the creation of accessible and affordable tools and technologies that allow broader biomedical communities to analyze carbohydrate structure and function, connect glycan-related measurements to other biomolecular data types, and ultimately accelerate discovery in areas where glycosylation and carbohydrate biology play key roles.
The mechanism is a U01 cooperative agreement, which typically means NIH expects substantial programmatic involvement during the project period compared with a standard research grant. Rather than funding an isolated research effort, a U01 commonly supports team-based development work with defined milestones, coordination with NIH program staff, and an expectation that the outputs will be broadly usable by the community. In practice, that often translates into deliverables like interoperable software tools, shared data standards or ontologies, web-based platforms, pipelines for integrating multiple data types, and user-friendly interfaces that make glycoscience data easier to find, interpret, and compare alongside gene, protein, and lipid datasets.
Administratively, the opportunity was issued by the U.S. Department of Health and Human Services through the NIH. It is categorized as discretionary funding, with a health-related activity category, and is associated with CFDA number 93.310. The funding opportunity number is RFA-RM-16-021, indicating it is a Request for Applications (RFA) and tied to the NIH Common Fund (often denoted by the RM activity code). The opportunity was created on September 16, 2016, with an original closing date of November 28, 2016, so it reflects a specific historical funding round rather than an open, ongoing solicitation.
In terms of scale, the award ceiling was listed at $1,500,000, and NIH expected to make 1 award. That combination usually implies a relatively focused, high-impact project intended to produce a significant shared resource, or a coordinated platform that can serve as infrastructure for many downstream users. A single expected award also suggests NIH may have been seeking a flagship effort to establish a strong foundation for glycan data integration, potentially to be used across multiple projects or programs.
Eligibility is broad and includes a wide range of organizations: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding universities where specified); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the additional eligibility language. This wide eligibility aligns with the practical, translational nature of tool and resource development, where strong candidates could come from academic groups, research institutes, nonprofits focused on data resources, or private-sector developers with relevant technical expertise.
Overall, the opportunity is best understood as an NIH Common Fund investment in making glycoscience data more usable and more connected to the rest of modern biomedical data science. By supporting tools that integrate carbohydrate and glycoconjugate data with gene, protein, and lipid data, the program aims to make glycan biology easier to study, easier to interpret, and more routinely included in research on mechanisms of disease, diagnostics, and therapeutic development.
Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The opportunity is titled "Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Data in the Context of Comparable Gene, Protein, and Lipid Data (U01)."
Which agency is offering this grant?
The opportunity was issued by the U.S. Department of Health and Human Services through the National Institutes of Health (NIH).
What NIH program area is this associated with?
It sits within the NIH Common Fund program area called Accelerating Translation of Glycoscience Integration and Accessibility.
What is the main purpose of this opportunity?
The goal is to build practical, easy-to-use resources that help researchers integrate and analyze carbohydrate (glycan) and glycoconjugate data in a streamlined way that is comparable to how gene, protein, and lipid data are commonly handled.
What problem or gap is this funding meant to address?
It targets a long-standing gap where carbohydrate and glycoconjugate biology is important to health and disease, but the supporting data, analytical approaches, and informatics infrastructure have historically been harder to access and harder to integrate with more standardized genomics, proteomics, and lipidomics ecosystems.
What kinds of outputs or deliverables does this opportunity emphasize?
The emphasis is on informatics and usability, with expected outputs often taking the form of broadly usable resources such as interoperable software tools, shared data standards or ontologies, web-based platforms, pipelines for integrating multiple biomolecular data types, and user-friendly interfaces that make glycoscience data easier to find, interpret, and compare.
What does the "data integration and analysis tools" focus imply?
It implies a strong focus on building accessible and affordable tools and technologies that enable the broader biomedical community to analyze carbohydrate structure and function and connect glycan-related measurements to other biomolecular data types.
What is the funding mechanism?
The mechanism is a U01 cooperative agreement.
What does a U01 cooperative agreement generally mean for how the project is run?
A U01 typically involves substantial NIH programmatic involvement during the project period compared with a standard research grant. It commonly supports team-based development work with defined milestones, coordination with NIH program staff, and an expectation that the outputs will be broadly usable by the research community.
Is this opportunity aimed at basic research or resource/tool development?
Based on the description, it is aimed primarily at tool and resource development (especially informatics, integration, and usability), rather than funding an isolated research project.
What types of scientific data are expected to be integrated?
The opportunity specifically highlights integration and analysis of carbohydrate and glycoconjugate data in the context of comparable gene, protein, and lipid data.
What kinds of scientific areas could benefit from these tools?
The opportunity is intended to accelerate discovery in areas where glycosylation and carbohydrate biology play key roles, including broader biomedical research on health and disease.
What is the funding opportunity number?
The funding opportunity number is RFA-RM-16-021.
What does it mean that the opportunity is an RFA?
RFA stands for Request for Applications, indicating a defined solicitation tied to a specific program goal and time window (as opposed to an always-open program).
What CFDA number is associated with this opportunity?
The associated CFDA number is 93.310.
How much funding was available per award (maximum)?
The award ceiling listed was $1,500,000.
How many awards were expected?
NIH expected to make 1 award.
What does it suggest that only one award was expected?
It suggests the solicitation may have been aiming for a focused, high-impact, flagship effort to establish a strong foundation or shared infrastructure for glycan data integration that could serve many downstream users.
When was this opportunity created, and when did it close?
The opportunity was created on September 16, 2016, and had an original closing date of November 28, 2016.
Is this an ongoing, currently open funding opportunity?
No. The information provided indicates it reflects a specific historical funding round with an original closing date of November 28, 2016.
How is this opportunity categorized in terms of funding type and activity?
It is categorized as discretionary funding, with a health-related activity category.
Who is eligible to apply?
Eligibility is broad and includes state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding universities where specified); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the additional eligibility language.
Does the opportunity allow applications from for-profit organizations?
Yes. The eligibility list includes for-profit organizations other than small businesses, as well as small businesses.
Does the opportunity allow applications from nonprofit organizations?
Yes. The eligibility list includes nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status (excluding universities where specified).
Does the opportunity allow applications from universities and colleges?
Yes. The eligibility list includes public and state-controlled institutions of higher education and private institutions of higher education.
Does the opportunity allow applications from government entities?
Yes. The eligibility list includes state governments, county governments, local governments, special district governments, and independent school districts.
Does the opportunity allow applications from tribal entities?
Yes. The eligibility list includes federally recognized Native American tribal governments and other tribal organizations.
Why is this opportunity connected to the NIH Common Fund?
It is described as an NIH Common Fund investment intended to lower barriers to glycoscience and make glycan-related data more usable and more connected to mainstream biomedical data science.
What is the overarching intended impact?
The intended impact is to make glycoscience data easier to study, interpret, and routinely include in biomedical research by supporting tools that integrate carbohydrate and glycoconjugate data with gene, protein, and lipid data.
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