Opportunity Information: Apply for RFA RM 14 012
Apply for RFA RM 14 012
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Data Integration and Analysis Tools Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Structural, Analytical, and Interaction Data in the Context of Comparable Gene, Protein, and Lipid Data (R34)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Sep 30, 2014 and posted on Sep 30, 2014.
- Applicants must submit their applications by Dec 10, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments County governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) State governments Special district governments Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
This NIH Common Fund opportunity (RFA-RM-14-012) is a planning and preliminary research grant (R34) under the program "Accelerating Translation of Glycoscience: Integration and Accessibility." The basic problem it targets is that carbohydrates (glycans) and glycoconjugates are critically important in biology and disease, but many researchers avoid glycan-focused discovery because the molecules are complex and the tools and data resources are harder to use than those available for genes, proteins, and lipids. The broader Common Fund program is investing in three connected areas: easier methods and technologies for carbohydrate synthesis, more accessible tools for probing and analyzing carbohydrates, and better carbohydrate data integration and analysis tools. This particular FOA focuses on that third area, specifically on early-stage work that prepares the field for a larger, later effort.
The purpose of the R34 is to support preliminary research and, just as importantly, the formation and organization of research teams that can lay the foundation for an inclusive, community-driven set of resources. The end goal is to make it easier to integrate and analyze carbohydrate and glycoconjugate structural data, analytical data, and interaction data, and to do so in a way that aligns with and connects to comparable datasets for genes, proteins, and lipids. In practical terms, the FOA is aimed at seeding the collaborations, standards discussions, prototype development, and consensus-building needed so that the eventual full-scale development (to be solicited under a subsequent FOA) is grounded in real community needs and is interoperable with the wider bioinformatics ecosystem.
The scientific scope centers on data integration and analysis for glycans and glycoconjugates. That includes how to represent glycan structures, how to connect structural representations to experimental/analytical outputs, and how to capture and use interaction information (for example, binding relationships, recognition events, or other molecular interactions involving glycans). A key theme is context: these glycoscience data should not live in isolation, but should be usable alongside gene, protein, and lipid data in ways that biomedical researchers already expect. The emphasis on accessibility and affordability also signals an expectation that resulting approaches will lower barriers for non-specialists and encourage broader adoption across biomedical fields.
Administratively, this is a discretionary grant opportunity from the National Institutes of Health (NIH), categorized under Health, with assistance listing CFDA 93.310 (Trans-NIH Research Support). NIH anticipated making about 5 awards under this FOA, with an estimated total funding amount of $1,000,000. The listed award ceiling is $150,000, and there is no cost-sharing or matching requirement.
Eligibility is broad and includes many types of domestic organizations such as public and private institutions of higher education, nonprofits (both 501(c)(3) and certain non-501(c)(3) entities), small businesses, other for-profit organizations (that are not small businesses), and various units of government (city/township, county, state, special district, and others). It also includes a wide range of mission- or population-focused institutions and organizations, including HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, eligible federal agencies, and faith-based or community-based organizations. Foreign organizations and foreign institutions are not eligible to apply directly, and non-U.S. components of U.S. organizations are also not eligible to apply; however, foreign components (as NIH defines them in its policy statement) are allowed, which typically means certain international collaborations or project elements can be included under NIH rules even when the applicant organization itself must be U.S.-based.
The timeline reflects that the FOA was posted and created on September 30, 2014, with an original and current closing date of December 10, 2014, and an archive date of January 10, 2015. The full announcement was hosted by NIH (with an additional information link to the NIH grants guide page), and NIH provided standard support contacts through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
Overall, the opportunity is best understood as a catalyst and organizing mechanism for the glycoscience data community: it is meant to fund the early, preparatory work required to build shared, user-friendly data integration and analysis resources so carbohydrate and glycoconjugate information can be compared, combined, and analyzed alongside mainstream omics data. The R34 stage is explicitly positioned as groundwork for a later, larger funding opportunity that would support full development and broader deployment of the resulting community-driven resources.
Frequently Asked Questions (FAQs)
What is the name and identifier of this NIH funding opportunity?
This opportunity is an NIH Common Fund funding opportunity announcement (FOA) titled "Accelerating Translation of Glycoscience: Integration and Accessibility" and identified as RFA-RM-14-012.
What grant mechanism is being used?
The FOA uses the R34 mechanism, described here as a planning and preliminary research grant.
What is the core problem the program is trying to solve?
The program targets a practical barrier in biomedical research: carbohydrates (glycans) and glycoconjugates are important in biology and disease, but many researchers avoid glycan-focused discovery because glycan molecules are complex and the supporting tools and data resources are harder to use than those available for genes, proteins, and lipids.
How does this R34 FOA fit within the broader NIH Common Fund glycoscience effort?
The broader Common Fund program is investing in three connected areas: (1) easier methods and technologies for carbohydrate synthesis, (2) more accessible tools for probing and analyzing carbohydrates, and (3) better carbohydrate data integration and analysis tools. This specific FOA focuses on the third area and supports early-stage work meant to prepare the field for a later, larger effort.
What is the main purpose of this R34 award?
The R34 is intended to support preliminary research and to support the formation and organization of research teams. The goal is to lay the groundwork for an inclusive, community-driven set of resources that make glycoscience data easier to integrate and analyze.
What is the long-term goal of the work funded by this FOA?
The end goal is to make it easier to integrate and analyze carbohydrate and glycoconjugate structural data, analytical data, and interaction data, and to align those resources with comparable datasets for genes, proteins, and lipids so researchers can use them together.
Is this FOA meant to fund full-scale platform development?
No. This FOA is positioned as an early-stage catalyst. It supports seeding collaborations, standards discussions, prototype development, and consensus-building so that a later, subsequent FOA can fund full-scale development and broader deployment grounded in community needs.
What scientific area and topic does this FOA emphasize?
The scientific scope centers on data integration and analysis for glycans and glycoconjugates, with an emphasis on making those data usable in ways biomedical researchers expect when working with gene, protein, and lipid datasets.
What kinds of glycoscience data are within scope?
The FOA highlights integration and analysis of (1) carbohydrate and glycoconjugate structural data, (2) analytical or experimental data tied to those structures, and (3) interaction data involving glycans (such as binding relationships, recognition events, or other molecular interactions).
What does the FOA mean by "context" and interoperability with other omics data?
A key theme is that glycoscience data should not live in isolation. The FOA emphasizes that glycan and glycoconjugate information should be represented and integrated so it can be compared, combined, and analyzed alongside mainstream datasets for genes, proteins, and lipids, connecting to the wider bioinformatics ecosystem.
Why does the FOA emphasize accessibility and affordability?
The FOA signals an expectation that resulting approaches will lower barriers for non-specialists and encourage broader adoption across biomedical fields, addressing the historical difficulty of using glycan-focused tools and resources.
What types of activities does this R34 appear intended to support?
Based on the description, the R34 is aimed at early-stage, preparatory activities such as organizing research teams, building collaborations, holding standards and consensus discussions, developing prototypes, and performing preliminary research needed to inform an eventual full-scale resource development effort.
How many awards did NIH anticipate making under this FOA?
NIH anticipated making about 5 awards under this FOA.
What was the estimated total funding amount for this FOA?
The estimated total funding amount listed for this FOA was $1,000,000.
What is the award ceiling for this opportunity?
The listed award ceiling is $150,000.
Is cost sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement.
Which federal agency and program are offering this opportunity?
This is a discretionary grant opportunity from the National Institutes of Health (NIH) under the NIH Common Fund.
How is the opportunity categorized and what assistance listing is provided?
It is categorized under Health, with assistance listing CFDA 93.310 (Trans-NIH Research Support).
Who is eligible to apply?
Eligibility is broad for domestic organizations and includes public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, other for-profit organizations that are not small businesses, and various units of government (such as city/township, county, state, and special districts).
Are mission- or population-focused institutions included in eligibility?
Yes. The eligibility list includes institutions and organizations such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, eligible federal agencies, and faith-based or community-based organizations.
Can foreign organizations apply directly?
No. Foreign organizations and foreign institutions are not eligible to apply directly under this FOA.
Are non-U.S. components of U.S. organizations eligible to apply?
No. Non-U.S. components of U.S. organizations are also not eligible to apply.
Are foreign components allowed in any form?
Yes. The FOA states that foreign components (as NIH defines them in its policy statement) are allowed, which typically means certain international collaborations or project elements may be included under NIH rules even though the applicant organization must be U.S.-based.
When was the FOA posted and created?
The FOA was posted and created on September 30, 2014.
What was the application closing date?
The original and current closing date listed is December 10, 2014.
When was the FOA archived?
The archive date listed is January 10, 2015.
Where was the full announcement hosted?
The full announcement was hosted by NIH, with an additional information link to the NIH grants guide page.
Who should be contacted for access or linking issues related to the announcement?
NIH provided standard support contacts through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
How should this opportunity be understood at a high level?
It is best understood as a catalyst and organizing mechanism for the glycoscience data community, funding early preparatory work required to build shared, user-friendly data integration and analysis resources so carbohydrate and glycoconjugate information can be used alongside mainstream omics data.
Does the FOA indicate that additional funding opportunities may follow?
Yes. The R34 stage is explicitly described as groundwork for a later, larger funding opportunity to be solicited under a subsequent FOA that would support full development and broader deployment.
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