Opportunity Information: Apply for RFA RM 12 010
Apply for RFA RM 12 010
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Data Management and Resource Repository (DMRR) on Extracellular RNA (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Aug 3, 2012 and posted on Aug 3, 2012.
- Applicants must submit their applications by Nov 13, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Public housing authorities/Indian housing authorities Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) County governments Independent school districts Native American tribal governments (Federally recognized) Special district governments Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The National Institutes of Health (NIH) offered this funding opportunity (RFA-RM-12-010) to establish and support a single Data Management Resource/Repository (DMRR) for the Extracellular RNA (ExRNA) Communication Program (ERCP). The award mechanism is a U54 cooperative agreement, which typically means NIH staff would be actively involved in the project through substantial scientific or programmatic collaboration rather than operating purely at arm's length. The main idea is to create a central hub that connects and coordinates the work of all ERCP-funded projects, while also serving the broader research community by making ExRNA-related standards, protocols, and datasets easier to find, use, and compare.
At the core of the announcement is the expectation that the DMRR will build and maintain an "ExRNA Atlas" that functions as a community-wide resource. In practical terms, this implies a structured repository and data management system capable of aggregating and organizing ExRNA data generated across multiple studies, along with the accompanying metadata, documentation, and methodological details that make the data interpretable and reusable. The opportunity emphasizes integration, meaning the repository is not just a storage site but a coordinating platform intended to harmonize efforts across the overall program. This kind of resource typically supports consistency in data formats, annotation practices, and submission requirements so that results from different laboratories and projects can be compared or combined more reliably.
The FOA sits in the Health funding activity category and was posted on August 3, 2012, with an original and current closing date of November 13, 2012, and an archive date of December 14, 2012. NIH anticipated making one award, reflecting the goal of having a single, centralized DMRR rather than multiple competing repositories. The estimated total funding was $2.5 million, with an award ceiling of $2.0 million, and there was no cost-sharing or matching requirement. The CFDA listing provided is 93.310 (Trans-NIH Research Support), which is consistent with an NIH-wide initiative supporting shared infrastructure and program coordination.
Eligibility was broad across U.S.-based organizational types, including public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses), and multiple levels of government (state, county, city/township, special district, and independent school districts). The eligibility section also explicitly includes a wide range of mission-focused institutions and community entities such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and eligible federal agencies. Non-domestic (non-U.S.) entities (foreign institutions) were not eligible to apply directly, but non-domestic components of U.S. organizations could participate, and foreign components were allowed as defined under the NIH Grants Policy Statement, which is a common way NIH enables international collaboration without making the prime award to a foreign institution.
In short, this FOA was designed to fund one NIH-partnered coordinating center that would provide the data infrastructure for the ERCP, with a strong emphasis on unifying the program's outputs and delivering a durable, community-facing ExRNA Atlas containing standardized protocols, standards, and curated datasets. For applicants, the opportunity implied both technical responsibilities (data intake, curation, repository architecture, access mechanisms) and programmatic responsibilities (integration across ERCP components and ongoing coordination with NIH under the cooperative agreement model). For full details, NIH directed applicants to the official posting at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-12-010.html and provided NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
Frequently Asked Questions (FAQs)
What is the funding opportunity number and sponsor for this grant?
This funding opportunity is RFA-RM-12-010 and it was offered by the National Institutes of Health (NIH).
What is the main purpose of this funding opportunity?
The purpose is to establish and support a single Data Management Resource/Repository (DMRR) for the Extracellular RNA (ExRNA) Communication Program (ERCP). The DMRR is intended to act as a central hub that connects and coordinates ERCP-funded projects and also serves the broader research community by improving access to ExRNA-related standards, protocols, and datasets.
What award mechanism is being used?
The award mechanism is a U54 cooperative agreement.
What does it mean that this is a U54 cooperative agreement?
A U54 cooperative agreement typically indicates substantial scientific or programmatic involvement by NIH staff. Rather than functioning purely at arm's length, the project is expected to involve active collaboration between the awardee and NIH.
How many awards did NIH expect to make under this announcement?
NIH anticipated making one award, reflecting the goal of having a single, centralized DMRR rather than multiple repositories.
What is the "ExRNA Atlas" and what is expected of it?
The FOA expects the DMRR to build and maintain an "ExRNA Atlas" as a community-wide resource. In practical terms, this implies a structured repository and data management system that aggregates and organizes ExRNA data across multiple studies along with metadata, documentation, and methodological details needed for interpretation and reuse.
Is this repository intended to be more than a storage site?
Yes. The announcement emphasizes integration and coordination. The repository is described as a coordinating platform intended to harmonize efforts across the overall program, not just a place to store files.
What types of content is the DMRR expected to make easier to find and use?
Based on the FOA summary, the DMRR is expected to improve the discoverability and usability of ExRNA-related standards, protocols, and datasets, supporting easier comparison and reuse across studies.
What does "integration" mean in the context of this FOA?
Integration refers to connecting and coordinating the work of all ERCP-funded projects through a central hub, while harmonizing program outputs so results from different labs or projects can be compared or combined more reliably.
Does the FOA indicate any standardization expectations?
Yes. It highlights harmonization and consistency, implying the DMRR should support consistent data formats, annotation practices, and submission requirements so that ExRNA results across projects are more comparable.
What technical responsibilities are implied for the DMRR?
The description implies responsibilities such as data intake, curation, repository architecture, inclusion of metadata and documentation, and mechanisms that allow the research community to access and use curated datasets.
What programmatic responsibilities are implied for the DMRR?
The DMRR is expected to coordinate and integrate across ERCP components and to work with NIH under the cooperative agreement model, which anticipates ongoing collaboration and programmatic involvement by NIH staff.
What is the funding activity category?
The funding activity category is Health.
When was the FOA posted and what were the key dates?
The FOA was posted on August 3, 2012. The original and current closing date was November 13, 2012. The archive date was December 14, 2012.
What was the estimated total funding and award ceiling?
The estimated total funding was $2.5 million, and the award ceiling was $2.0 million.
Is cost sharing or matching required?
No. The FOA indicates there was no cost-sharing or matching requirement.
What CFDA number is associated with this opportunity?
The CFDA listing provided is 93.310, described as Trans-NIH Research Support.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizational types, including public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) entities); for-profit organizations (including small businesses); and multiple levels of government (state, county, city/township, special district, and independent school districts).
Are mission-focused and community-based institutions included in the eligible applicant types?
Yes. The eligibility section explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and eligible federal agencies.
Can a non-U.S. (foreign) institution apply as the primary applicant?
No. Non-domestic (non-U.S.) entities were not eligible to apply directly as the applicant organization.
Can foreign components participate in the project in any way?
Yes. The FOA notes that non-domestic components of U.S. organizations could participate, and foreign components were allowed as defined under the NIH Grants Policy Statement.
Where can applicants find the official FOA posting?
The official posting is available at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-12-010.html
Who is listed for help with access or linking issues related to the posting?
NIH provided NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
Browse more opportunities from the same category: Health
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