Opportunity Information: Apply for PA 13 155
Apply for PA 13 155
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Development and Characterization of Animal Models for Aging Research (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.866 Aging Research.
- This funding opportunity was created on Mar 22, 2013 and posted on Mar 22, 2013.
- Applicants must submit their applications by Sep 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts For profit organizations other than small businesses City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities County governments Private institutions of higher education Special district governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH grant opportunity titled "Development and Characterization of Animal Models for Aging Research (R01)" (Funding Opportunity Number PA 13-155) was a discretionary, investigator-initiated research grant solicitation using the NIH R01 mechanism. Its central aim was to expand and strengthen the toolkit of animal and other biological model systems available for aging research by supporting projects that develop new models, improve existing ones, and generate the kind of careful characterization data that makes models reliable, comparable across labs, and broadly useful to the research community. In practical terms, the announcement was focused less on testing a single aging hypothesis in a narrow context and more on building or upgrading model systems that can serve as platforms for many future studies on the biology of aging and age-related functional change.
The scientific purpose was to promote research that develops, characterizes, refines, and enhances model systems relevant to aging. This includes work that establishes or improves animal models that better capture key features of aging processes, clarifies what a model can and cannot represent, and improves reproducibility through standardized phenotyping, validated endpoints, and well-described husbandry or experimental conditions. Typical projects under a program like this often involve defining age-associated trajectories in physiology or behavior, benchmarking biomarkers, mapping how genetics and environment shape aging outcomes, or refining protocols so that a model more faithfully mirrors aspects of human aging. The emphasis on characterization is important: it signals support for rigorous baseline data collection, longitudinal measures, and documentation of variability and confounding factors, which are often essential for making a model valuable beyond a single study.
Administratively, this opportunity fell under the National Institutes of Health and was categorized as a health-related funding activity. The CFDA numbers listed were 93.866 (Aging Research) and 93.173 (Research Related to Deafness and Communication Disorders), indicating that the initiative was aligned primarily with aging research while also being relevant to communication disorders and sensory systems where aging can play a major role. The funding instrument was a grant, specifically an R01, which generally supports multi-year, hypothesis-driven or resource-building research projects with substantial scope. There was no cost sharing or matching requirement, meaning applicants were not required to commit institutional matching funds as a condition of award.
Eligibility was broad and included many common NIH applicant types: public and private institutions of higher education, public and state-controlled institutions, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), and various levels of government (state, county, city/township, special districts), as well as independent school districts and public housing authorities/Indian housing authorities. Tribal entities were explicitly included, both federally recognized tribal governments and other tribal organizations. The announcement also allowed participation by a wide range of mission-focused institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based and community-based organizations and eligible federal agencies. Importantly, non-U.S. entities were eligible to apply: foreign organizations and foreign institutions could submit applications, non-domestic components of U.S. organizations were eligible, and foreign components (as defined by NIH policy) were permitted, which signals NIH interest in leveraging global expertise and unique resources for aging model development.
In terms of timing, the opportunity was posted and created on March 22, 2013. The original and final closing date listed was September 7, 2016, after which the opportunity was archived on October 8, 2016. That means the specific announcement is no longer open for applications, but it remains a useful reference point for understanding NIH priorities around animal models in aging, and similar initiatives may exist under newer funding announcements or related NIH program areas.
The official additional information link associated with the announcement was provided through the NIH Grants Guide: http://grants.nih.gov/grants/guide/pa-files/PA-13-155.html. For administrative or technical issues accessing the announcement, the listed contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is a support contact for problems with the electronic posting or linking rather than a scientific program contact.
Overall, PA 13-155 was designed to move the field forward by improving the foundations of aging research: better models, better characterization, and better refinement so that studies of aging mechanisms and age-related disease can be conducted with stronger validity, clearer interpretation, and greater reproducibility across research settings.
FAQs: Development and Characterization of Animal Models for Aging Research (R01) (PA-13-155)
What is the title of this NIH funding opportunity?
The opportunity is titled "Development and Characterization of Animal Models for Aging Research (R01)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA 13-155.
What NIH funding mechanism did this announcement use?
It used the NIH R01 mechanism, which is an NIH research project grant mechanism.
What type of grant was this (competitive vs. discretionary, investigator-initiated vs. directed)?
It was described as a discretionary, investigator-initiated research grant solicitation.
What was the central aim of PA 13-155?
The central aim was to expand and strengthen the toolkit of animal and other biological model systems available for aging research by supporting projects that develop new models, improve existing ones, and generate careful characterization data to make models reliable, comparable across labs, and broadly useful to the research community.
What kinds of projects was this opportunity intended to support?
It was intended to support research that develops, characterizes, refines, and enhances model systems relevant to aging. This includes establishing or improving animal models that better capture key features of aging processes and producing the characterization needed to clarify what a model can and cannot represent.
Was this announcement more focused on testing a specific aging hypothesis or on building model resources?
The announcement emphasized building or upgrading model systems that can serve as platforms for many future studies, rather than testing a single aging hypothesis in a narrow context.
What does "characterization" mean in the context of this opportunity?
Characterization refers to rigorous baseline data collection and detailed documentation that makes a model reliable and broadly usable. The description highlights standardized phenotyping, validated endpoints, well-described husbandry or experimental conditions, longitudinal measures, and documentation of variability and confounding factors.
Why was reproducibility across labs emphasized?
The opportunity explicitly sought careful characterization data so that models could be comparable across laboratories and broadly useful, which supports reproducibility through standardized phenotyping, validated endpoints, and clearly described conditions.
What are examples of activities that fit the scientific purpose described?
Examples mentioned include defining age-associated trajectories in physiology or behavior, benchmarking biomarkers, mapping how genetics and environment shape aging outcomes, and refining protocols so a model more faithfully mirrors aspects of human aging.
Which federal agency offered this opportunity?
This opportunity fell under the National Institutes of Health (NIH).
What was the funding activity category?
It was categorized as a health-related funding activity.
What CFDA numbers were associated with this opportunity?
The CFDA numbers listed were 93.866 (Aging Research) and 93.173 (Research Related to Deafness and Communication Disorders).
What do the listed CFDA numbers suggest about the scientific alignment?
They indicate the initiative aligned primarily with aging research (93.866) while also being relevant to deafness and communication disorders (93.173), including sensory systems where aging can play a major role.
Was cost sharing or matching required?
No. The announcement stated there was no cost sharing or matching requirement.
What types of organizations were eligible to apply?
Eligibility was broad and included public and private institutions of higher education; public and state-controlled institutions; nonprofits with or without 501(c)(3) status; for-profit organizations (including small businesses); and multiple levels of government (state, county, city/township, and special districts), as well as independent school districts and public housing authorities/Indian housing authorities.
Were tribal entities eligible?
Yes. Both federally recognized tribal governments and other tribal organizations were explicitly included.
Were mission-focused and minority-serving institutions included in eligibility?
Yes. The announcement allowed participation by institutions such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based and community-based organizations and eligible federal agencies.
Could for-profit organizations apply?
Yes. For-profit organizations, including small businesses, were listed as eligible applicants.
Were non-U.S. (foreign) organizations eligible to apply?
Yes. Foreign organizations and foreign institutions could submit applications, and non-domestic components of U.S. organizations were eligible.
Were foreign components allowed under NIH policy for this opportunity?
Yes. Foreign components (as defined by NIH policy) were permitted.
What does allowing foreign applicants and foreign components signal about NIH intent?
The description indicates it signaled NIH interest in leveraging global expertise and unique resources for aging model development.
When was this opportunity posted and created?
It was posted and created on March 22, 2013.
What was the closing date for applications?
The original and final closing date listed was September 7, 2016.
Is PA 13-155 still open for applications?
No. The announcement closed on September 7, 2016 and was archived on October 8, 2016.
When was the opportunity archived?
It was archived on October 8, 2016.
Where can the official NIH Grants Guide listing be found?
The official additional information link provided was: http://grants.nih.gov/grants/guide/pa-files/PA-13-155.html.
Who was listed as the contact for administrative or technical issues with accessing the announcement?
The listed contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Is the OER Webmaster a scientific program contact for project fit questions?
The description indicates this is a support contact for problems with the electronic posting or linking, rather than a scientific program contact.
What broader impact was PA 13-155 intended to have on aging research?
It was designed to improve the foundations of aging research by enabling better models, better characterization, and better refinement so that studies of aging mechanisms and age-related functional change could be conducted with stronger validity, clearer interpretation, and greater reproducibility across research settings.
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